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Low-dose computed tomography (CT) denoising is crucial for reduced radiation exposure while ensuring diagnostically acceptable image quality. Despite significant advancements driven by deep learning (DL) in recent years, existing DL-based…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Zhihao Chen , Qi Gao , Zilong Li , Junping Zhang , Yi Zhang , Jun Zhao , Hongming Shan

The generalization of deep learning-based low-dose computed tomography (CT) reconstruction models to doses unseen in the training data is important and remains challenging. Previous efforts heavily rely on paired data to improve the…

Image and Video Processing · Electrical Eng. & Systems 2025-06-30 Qi Gao , Zhihao Chen , Dong Zeng , Junping Zhang , Jianhua Ma , Hongming Shan

Low-dose computed tomography (LDCT) reduces radiation exposure but suffers from image artifacts and loss of detail due to quantum and electronic noise, potentially impacting diagnostic accuracy. Transformer combined with diffusion models…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Qiqing Liu , Guoquan Wei , Zekun Zhou , Yiyang Wen , Liu Shi , Qiegen Liu

Low-dose Computed Tomography (LDCT) reconstruction is an important task in medical image analysis. Recent years have seen many deep learning based methods, proved to be effective in this area. However, these methods mostly follow a…

Image and Video Processing · Electrical Eng. & Systems 2023-02-08 Runyi Li

Denoising low-dose computed tomography (CT) images is a critical task in medical image computing. Supervised deep learning-based approaches have made significant advancements in this area in recent years. However, these methods typically…

Image and Video Processing · Electrical Eng. & Systems 2023-07-17 Xuan Liu , Yaoqin Xie , Jun Cheng , Songhui Diao , Shan Tan , Xiaokun Liang

Current methods based on deep learning for self-supervised low-dose CT (LDCT) reconstruction, while reducing the dependence on paired data, face the problem of significantly decreased generalization when training with single-dose data and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Guoquan Wei , Liu Shi , Zekun Zhou , Mohan Li , Cunfeng Wei , Wenzhe Shan , Qiegen Liu

Being low-level radiation exposure and less harmful to health, low-dose computed tomography (LDCT) has been widely adopted in the early screening of lung cancer and COVID-19. LDCT images inevitably suffer from the degradation problem caused…

Image and Video Processing · Electrical Eng. & Systems 2022-04-19 Kecheng Chen , Jiayu Sun , Jiang Shen , Jixiang Luo , Xinyu Zhang , Xuelin Pan , Dongsheng Wu , Yue Zhao , Miguel Bento , Yazhou Ren , Xiaorong Pu

Deep learning is a very promising technique for low-dose computed tomography (LDCT) image denoising. However, traditional deep learning methods require paired noisy and clean datasets, which are often difficult to obtain. This paper…

Image and Video Processing · Electrical Eng. & Systems 2023-08-15 Yuting Zhu , Qiang He , Yudong Yao , Yueyang Teng

Low-dose computed tomography (LDCT) reduces patient radiation exposure but introduces substantial noise that degrades image quality and hinders diagnostic accuracy. Existing denoising approaches often require many diffusion steps, limiting…

Medical Physics · Physics 2025-10-29 Qiang Li , Mojtaba Safari , Shansong Wang , Huiqiao Xie , Jie Ding , Tonghe Wang , Xiaofeng Yang

Score-based diffusion models have significantly advanced generative deep learning for image processing. Measurement conditioned models have also been applied to inverse problems such as CT reconstruction. However, the conventional approach,…

Medical Physics · Physics 2025-02-24 Matthew Tivnan , Dufan Wu , Quanzheng Li

Recently, Self-supervised learning methods able to perform image denoising without ground truth labels have been proposed. These methods create low-quality images by adding random or Gaussian noise to images and then train a model for…

Image and Video Processing · Electrical Eng. & Systems 2021-04-07 Dongkyu Won , Euijin Jung , Sion An , Philip Chikontwe , Sang Hyun Park

Computed tomography (CT) serves as an effective tool for lung cancer screening, diagnosis, treatment, and prognosis, providing a rich source of features to quantify temporal and spatial tumor changes. Nonetheless, the diversity of CT…

Image and Video Processing · Electrical Eng. & Systems 2023-10-10 Md Selim , Jie Zhang , Faraneh Fathi , Michael A. Brooks , Ge Wang , Guoqiang Yu , Jin Chen

Reducing scan times, radiation dose, and enhancing image quality for lower-performance scanners, are critical in low-dose PET imaging. Deep learning techniques have been investigated for PET image denoising. However, existing models have…

Sparse-view computed tomography (CT) reduces radiation exposure by subsampling projection views, but conventional reconstruction methods produce severe streak artifacts with undersampled data. While deep-learning-based methods enable…

Image and Video Processing · Electrical Eng. & Systems 2025-08-15 Jixiang Chen , Yiqun Lin , Yi Qin , Hualiang Wang , Xiaomeng Li

Computed tomography (CT) is one of the modalities for effective lung cancer screening, diagnosis, treatment, and prognosis. The features extracted from CT images are now used to quantify spatial and temporal variations in tumors. However,…

Image and Video Processing · Electrical Eng. & Systems 2023-03-28 Md Selim , Jie Zhang , Michael A. Brooks , Ge Wang , Jin Chen

Low-dose computed tomography (LDCT) is critical for minimizing radiation exposure, but it often leads to increased noise and reduced image quality. Traditional denoising methods, such as iterative optimization or supervised learning, often…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Debopom Sutradhar , Ripon Kumar Debnath , Mohaimenul Azam Khan Raiaan , Yan Zhang , Reem E. Mohamed , Sami Azam

Low dose computed tomography (LDCT) is desirable for both diagnostic imaging and image guided interventions. Denoisers are openly used to improve the quality of LDCT. Deep learning (DL)-based denoisers have shown state-of-the-art…

Image and Video Processing · Electrical Eng. & Systems 2020-12-08 Ti Bai , Biling Wang , Dan Nguyen , Bao Wang , Bin Dong , Wenxiang Cong , Mannudeep K. Kalra , Steve Jiang

Low-dose computed tomography (LDCT) became a clear trend in radiology with an aspiration to refrain from delivering excessive X-ray radiation to the patients. The reduction of the radiation dose decreases the risks to the patients but…

Image and Video Processing · Electrical Eng. & Systems 2021-02-05 Elvira Zainulina , Alexey Chernyavskiy , Dmitry V. Dylov

Low-dose computed tomography (LDCT) is an important topic in the field of radiology over the past decades. LDCT reduces ionizing radiation-induced patient health risks but it also results in a low signal-to-noise ratio (SNR) and a potential…

Image and Video Processing · Electrical Eng. & Systems 2022-10-03 Wenjun Xia , Qing Lyu , Ge Wang

A major challenge in computed tomography (CT) is how to minimize patient radiation exposure without compromising image quality and diagnostic performance. The use of deep convolutional (Conv) neural networks for noise reduction in Low-Dose…

Computer Vision and Pattern Recognition · Computer Science 2019-08-06 Chenyu You , Linfeng Yang , Yi Zhang , Ge Wang
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