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Early-stage Parkinson's disease (EarlyPD) detection from speech is clinically meaningful yet underexplored, and published results are hard to compare because studies differ in datasets, languages, tasks, evaluation protocols, and EarlyPD…

Audio and Speech Processing · Electrical Eng. & Systems 2026-05-15 Terry Yi Zhong , Cristian Tejedor-Garcia , Khiet P. Truong , Janna Maas , Louis ten Bosch , Bastiaan R. Bloem

Background: Dementia, particularly Alzheimer's Disease (AD), is a progressive neurodegenerative disorder marked by cognitive decline. Early detection, especially at the Mild Cognitive Impairment (MCI) stage, is essential for timely…

Signal Processing · Electrical Eng. & Systems 2025-10-16 Shivani Ranjan , Anant Jain , Robin Badal , Amit Kumar , Harshal Shende , Deepak Joshi , Pramod Yadav , Lalan Kumar

Speech impairments in Parkinson's disease (PD) provide significant early indicators for diagnosis. While models for speech-based PD detection have shown strong performance, their interpretability remains underexplored. This study…

Sound · Computer Science 2024-11-14 Eleonora Mancini , Francesco Paissan , Paolo Torroni , Mirco Ravanelli , Cem Subakan

Parkinson's disease (PD) is a slowly progressive debilitating neurodegenerative disease which is prominently characterised by motor symptoms. Indoor localisation, including number and speed of room to room transitions, provides a proxy…

Machine Learning · Computer Science 2022-05-13 Ferdian Jovan , Ryan McConville , Catherine Morgan , Emma Tonkin , Alan Whone , Ian Craddock

Historically, the analysis of stimulus-dependent time-frequency patterns has been the cornerstone of most electroencephalography (EEG) studies. The abnormal oscillations in high-frequency waves associated with psychotic disorders during…

Neurons and Cognition · Quantitative Biology 2023-01-05 Sadi Md. Redwan , Md Palash Uddin , Anwaar Ulhaq , Muhammad Imran Sharif

Parkinson's disease (PD) is a common neurodegenerative disease with a high degree of heterogeneity in its clinical features, rate of progression, and change of variables over time. In this work, we present a novel data-driven, network-based…

Applications · Statistics 2020-07-01 Sanjukta Krishnagopal , Rainer Von Coelln , Lisa M. Shulman , Michelle Girvan

Parkinson's Disease (PD) is a chronic and progressive neurological disorder that results in rigidity, tremors and postural instability. There is no definite medical test to diagnose PD and diagnosis is mostly a clinical exercise. Although…

Image and Video Processing · Electrical Eng. & Systems 2021-07-28 Shanmukh Alle , U. Deva Priyakumar

Parkinson's disease (PD), a neurodegenerative disorder, often manifests as speech and voice dysfunction. While utilizing voice data for PD detection has great potential in clinical applications, the widely used deep learning models…

Machine Learning · Computer Science 2023-09-26 Yicheng Wang , Xiaotian Han , Leisheng Yu , Na Zou

Parkinson's disease (PD) is a neurological disorder that has a variety of observable motor-related symptoms such as slow movement, tremor, muscular rigidity, and impaired posture. PD is typically diagnosed by evaluating the severity of…

Computer Vision and Pattern Recognition · Computer Science 2022-07-04 Mark Endo , Kathleen L. Poston , Edith V. Sullivan , Li Fei-Fei , Kilian M. Pohl , Ehsan Adeli

Parkinson's Disease (PD) is one of the most prevalent neurodegenerative diseases that affects tens of millions of Americans. PD is highly progressive and heterogeneous. Quite a few studies have been conducted in recent years on predictive…

Computer Vision and Pattern Recognition · Computer Science 2019-05-08 Xi Sheryl Zhang , Lifang He , Kun Chen , Yuan Luo , Jiayu Zhou , Fei Wang

Parkinson's disease (PD) is a neurodegenerative condition characterized by frequently changing motor symptoms, necessitating continuous symptom monitoring for more targeted treatment. Classical time series classification and deep learning…

Machine Learning · Computer Science 2025-06-03 Cedric Donié , Neha Das , Satoshi Endo , Sandra Hirche

In this paper, we aimed at reviewing present literature on employing nonlinear analysis in combination with machine learning methods, in depression detection or prediction task. We are focusing on an affordable data-driven approach,…

Signal Processing · Electrical Eng. & Systems 2019-09-10 Milena Čukić Radenković , Victoria Lopez Lopez

Background and Objective: It is commonly accepted that accurate monitoring of neurodegenerative diseases is crucial for effective disease management and delivery of medication and treatment. This research develops automatic clinical…

Neural and Evolutionary Computing · Computer Science 2022-05-31 Amir Dehsarvi , Jennifer Kay South Palomares , Stephen Leslie Smith

Parkinson's Disease (PD) often results in motor and cognitive impairments, including gait dysfunction, particularly in patients with freezing of gait (FOG). Current detection methods are either subjective or reliant on specialized gait…

Machine Learning · Computer Science 2026-01-14 Shomoita Jahid Mitin , Rodrigue Rizk , Maximilian Scherer , Thomas Koeglsperger , Daniel Lench , KC Santosh , Arun Singh

Freezing of gait (FoG) is a special symptom found in patients with Parkinson's disease (PD). Patients who have FoG abruptly lose the capacity to walk as they normally would. Accelerometers worn by patients can record movement data during…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Mahmudul Hasan

In the status quo, dementia is yet to be cured. Precise diagnosis prior to the onset of the symptoms can prevent the rapid progression of the emerging cognitive impairment. Recent progress has shown that Electroencephalography (EEG) is the…

PD is linked to faster brain aging. Sex is recognized as an important factor in PD, such that males are twice as likely as females to have the disease and have more severe symptoms and a faster progression rate. Despite previous research,…

Neurons and Cognition · Quantitative Biology 2023-09-20 Iman Beheshti , Samuel Booth , Ji Hyun Ko

In this modern era of overpopulation disease prediction is a crucial step in diagnosing various diseases at an early stage. With the advancement of various machine learning algorithms, the prediction has become quite easy. However, the…

Machine Learning · Computer Science 2022-03-23 Ishu Gupta , Vartika Sharma , Sizman Kaur , Ashutosh Kumar Singh

Fundamental knowledge in activity recognition of individuals with motor disorders such as Parkinson's disease (PD) has been primarily limited to detection of steady-state/static tasks (sitting, standing, walking). To date, identification of…

Signal Processing · Electrical Eng. & Systems 2021-10-13 Mahdieh Kazemimoghadam , Nicholas P. Fey

Parkinson's disease (PD) is projected to increase substantially due to population aging, making early diagnosis increasingly important, as timely detection may delay progression and reduce long-term complications. Retinal microvasculature…