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A wide range of optimization problems arising in machine learning can be solved by gradient descent algorithms, and a central question in this area is how to efficiently compress a large-scale dataset so as to reduce the computational…

Machine Learning · Computer Science 2022-10-11 Jiawei Huang , Ruomin Huang , Wenjie Liu , Nikolaos M. Freris , Hu Ding

Deploying continual object detection on microcontrollers (MCUs) with under 100KB memory requires efficient feature compression that can adapt to evolving task distributions. Existing approaches rely on fixed compression strategies (e.g.,…

Artificial Intelligence · Computer Science 2026-04-14 Bibin Wilson

The tremdendous advances in high-throughput sequencing technologies have made population-scale sequencing as performed in the 1000 Genomes project and the Genome of the Netherlands project possible. Next-generation sequencing has allowed…

Genomics · Quantitative Biology 2013-03-15 Tobias Marschall , Alexander Schönhuth

Gaussian Probability Path based Generative Models (GPPGMs) generate data by reversing a stochastic process that progressively corrupts samples with Gaussian noise. Despite state-of-the-art results in 3D molecular generation, their…

Machine Learning · Computer Science 2026-02-23 Jingxiang Qu , Wenhan Gao , Ruichen Xu , Yi Liu

Machine-generated data is rapidly growing and poses challenges for data-intensive systems, especially as the growth of data outpaces the growth of storage space. To cope with the storage issue, compression plays a critical role in storage…

Databases · Computer Science 2023-11-27 Jiujing Zhang , Zhitao Shen , Shiyu Yang , Lingkai Meng , Chuan Xiao , Wei Jia , Yue Li , Qinhui Sun , Wenjie Zhang , Xuemin Lin

Compressed Sensing MRI (CS-MRI) has provided theoretical foundations upon which the time-consuming MRI acquisition process can be accelerated. However, it primarily relies on iterative numerical solvers which still hinders their adaptation…

Computer Vision and Pattern Recognition · Computer Science 2018-06-12 Tran Minh Quan , Thanh Nguyen-Duc , Won-Ki Jeong

Next Generation Sequencing (NGS) platforms and, more generally, high-throughput technologies are giving rise to an exponential growth in the size of nucleotide sequence databases. Moreover, many emerging applications of nucleotide datasets…

Databases · Computer Science 2019-10-11 Ferdinando Montecuollo , Giovannni Schmid , Roberto Tagliaferri

The effectiveness of Retrieval-Augmented Generation (RAG) is highly dependent on how documents are chunked, that is, segmented into smaller units for indexing and retrieval. Yet, commonly used "one-size-fits-all" approaches often fail to…

Computation and Language · Computer Science 2026-03-27 Paulo Roberto de Moura Júnior , Jean Lelong , Annabelle Blangero

Gravitational-wave detection strategies are based on a signal analysis technique known as matched filtering. Despite the success of matched filtering, due to its computational cost, there has been recent interest in developing deep…

General Relativity and Quantum Cosmology · Physics 2022-11-03 Dwyer S. Deighan , Scott E. Field , Collin D. Capano , Gaurav Khanna

The growing demand for molecules with tailored properties in fields such as drug discovery and chemical engineering has driven advancements in computational methods for molecular design. Machine learning-based approaches for de-novo…

Machine Learning · Computer Science 2025-04-29 Nandan Joshi , Erhan Guven

This paper demonstrates the utility of organized numerical representations of genes in research involving flat string gene formats (i.e., FASTA/FASTQ5). FASTA/FASTQ files have several current limitations, such as their large file sizes,…

Genomics · Quantitative Biology 2023-08-11 Daniel H. Um , David A. Knowles , Gail E. Kaiser

In the recent years, there has been a significant improvement in the quality of samples produced by (deep) generative models such as variational auto-encoders and generative adversarial networks. However, the representation capabilities of…

Image and Video Processing · Electrical Eng. & Systems 2026-03-31 Shady Abu Hussein , Tom Tirer , Raja Giryes

In this thesis we propose new methods for crossover operator namely: cut on worst gene (COWGC), cut on worst L+R gene (COWLRGC) and Collision Crossovers. And also we propose several types of mutation operator such as: worst gene with random…

Neural and Evolutionary Computing · Computer Science 2018-01-26 Esra'a O Alkafaween

This thesis concerns sequential-access data compression, i.e., by algorithms that read the input one or more times from beginning to end. In one chapter we consider adaptive prefix coding, for which we must read the input character by…

Information Theory · Computer Science 2009-02-03 Travis Gagie

Stochastic gradient methods (SGMs) are the predominant approaches to train deep learning models. The adaptive versions (e.g., Adam and AMSGrad) have been extensively used in practice, partly because they achieve faster convergence than the…

Optimization and Control · Mathematics 2022-04-14 Yangyang Xu , Yibo Xu , Yonggui Yan , Colin Sutcher-Shepard , Leopold Grinberg , Jie Chen

Counterfeiting poses a significant challenge across multiple industries, leading to financial losses and health risks. While DNA-based molecular tagging has emerged as a promising anti-counterfeiting strategy, existing methods rely on…

Cryptography and Security · Computer Science 2025-03-07 Ali Tafazoli Yazdi , Peter Nejjar , Lena Hochrein

Miniature DNA sequencing hardware has begun to succeed in mobile contexts, driving demand for efficient machine learning at the edge. This domain leverages deep learning techniques familiar from speech and time-series analysis for both…

Hardware Architecture · Computer Science 2025-10-13 Sebastian Magierowski , Zhongpan Wu , Abel Beyene , Karim Hammad

With the wide adoption of language models for IR -- and specifically RAG systems -- the latency of the underlying LLM becomes a crucial bottleneck, since the long contexts of retrieved passages lead large prompts and therefore, compute…

Information Retrieval · Computer Science 2026-04-06 Cornelius Kummer , Lena Jurkschat , Michael Färber , Sahar Vahdati

Error-bounded lossy compression techniques have become vital for scientific data management and analytics, given the ever-increasing volume of data generated by modern scientific simulations and instruments. Nevertheless, assessing data…

Machine Learning · Computer Science 2025-12-29 Khondoker Mirazul Mumenin , Robert Underwood , Dong Dai , Jinzhen Wang , Sheng Di , Zarija Lukić , Franck Cappello

Text embedding and generative tasks are usually trained separately based on large language models (LLMs) nowadays. This causes a large amount of training cost and deployment effort. Context compression is also a challenging and pressing…

Computation and Language · Computer Science 2026-05-13 Zhongtao Miao , Qiyu Wu , Yoshimasa Tsuruoka