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Large language models (LLMs) exhibit impressive capabilities in generation tasks but are prone to producing harmful, misleading, or biased content, posing significant ethical and safety concerns. To mitigate such risks, representation…

Cryptography and Security · Computer Science 2025-11-17 Zeqing He , Zhibo Wang , Huiyu Xu , Hejun Lin , Wenhui Zhang , Zhixuan Chu

Detection limit (DL) has become an increasingly ubiquitous issue in statistical analyses of biomedical studies, such as cytokine, metabolite and protein analysis. In regression analysis, if an explanatory variable is left-censored due to…

We examine the linear regression problem in a challenging high-dimensional setting with correlated predictors where the vector of coefficients can vary from sparse to dense. In this setting, we propose a combination of probabilistic…

Methodology · Statistics 2025-05-13 Roman Parzer , Peter Filzmoser , Laura Vana-Gür

Federated Learning (FL) is a distributed machine learning setting that requires multiple clients to collaborate on training a model while maintaining data privacy. The unaddressed inherent sparsity in data and models often results in overly…

Machine Learning · Statistics 2025-12-30 Krishna Harsha Kovelakuntla Huthasana , Alireza Olama , Andreas Lundell

Differentially Private Stochastic Gradient Descent (DP-SGD) limits the amount of private information deep learning models can memorize during training. This is achieved by clipping and adding noise to the model's gradients, and thus…

Computer Vision and Pattern Recognition · Computer Science 2023-06-22 Florian A. Hölzl , Daniel Rueckert , Georgios Kaissis

Many classification approaches first represent a test sample using the training samples of all the classes. This collaborative representation is then used to label the test sample. It was a common belief that sparseness of the…

Computer Vision and Pattern Recognition · Computer Science 2015-12-01 Naveed Akhtar , Faisal Shafait , Ajmal Mian

Probabilistic graphical models are traditionally known for their successes in generative modeling. In this work, we advocate layered graphical models (LGMs) for probabilistic discriminative learning. To this end, we design LGMs in close…

Machine Learning · Computer Science 2019-02-04 Yuesong Shen , Tao Wu , Csaba Domokos , Daniel Cremers

Sparse representation has attracted much attention from researchers in fields of signal processing, image processing, computer vision and pattern recognition. Sparse representation also has a good reputation in both theoretical research and…

Computer Vision and Pattern Recognition · Computer Science 2016-02-24 Zheng Zhang , Yong Xu , Jian Yang , Xuelong Li , David Zhang

We consider the problem of learning a conditional Gaussian graphical model in the presence of latent variables. Building on recent advances in this field, we suggest a method that decomposes the parameters of a conditional Markov random…

Methodology · Statistics 2017-03-07 Benjamin Frot , Luke Jostins , Gil McVean

The generalized partially linear additive model (GPLAM) is a flexible and interpretable approach to building predictive models. It combines features in an additive manner, allowing each to have either a linear or nonlinear effect on the…

Methodology · Statistics 2018-03-29 Yin Lou , Jacob Bien , Rich Caruana , Johannes Gehrke

Although deep learning has achieved appealing results on several machine learning tasks, most of the models are deterministic at inference, limiting their application to single-modal settings. We propose a novel general-purpose framework…

Machine Learning · Computer Science 2020-10-12 Sameera Ramasinghe , Kanchana Ranasinghe , Salman Khan , Nick Barnes , Stephen Gould

In this paper, we consider the classic measurement error regression scenario in which our independent, or design, variables are observed with several sources of additive noise. We will show that our motivating example's replicated…

Applications · Statistics 2012-07-10 David J. Biagioni , Ryan Elmore , Wesley Jones

Sparse representations have been shown to be useful in deep reinforcement learning for mitigating catastrophic interference and improving the performance of agents in terms of cumulative reward. Previous results were based on a two step…

Machine Learning · Computer Science 2019-12-10 J. Fernando Hernandez-Garcia , Richard S. Sutton

Image generative models, particularly diffusion-based models, have surged in popularity due to their remarkable ability to synthesize highly realistic images. However, since these models are data-driven, they inherit biases from the…

Machine Learning · Computer Science 2025-03-18 Lin-Chun Huang , Ching Chieh Tsao , Fang-Yi Su , Jung-Hsien Chiang

Reconstructing ocean dynamics from observational data is fundamentally limited by the sparse, irregular, and Lagrangian nature of spatial sampling, particularly in subsurface and remote regions. This sparsity poses significant challenges…

Atmospheric and Oceanic Physics · Physics 2025-07-10 Niloofar Asefi , Leonard Lupin-Jimenez , Tianning Wu , Ruoying He , Ashesh Chattopadhyay

Sparsity-constrained optimization has wide applicability in machine learning, statistics, and signal processing problems such as feature selection and compressive Sensing. A vast body of work has studied the sparsity-constrained…

Machine Learning · Statistics 2013-07-17 Sohail Bahmani , Bhiksha Raj , Petros Boufounos

Learning low-dimensional representations of single-cell transcriptomics has become instrumental to its downstream analysis. The state of the art is currently represented by neural network models such as variational autoencoders (VAEs) which…

Machine Learning · Computer Science 2024-02-01 Viktoria Schuster , Anders Krogh

We introduce a novel generative framework for functions by integrating Implicit Neural Representations (INRs) and Transformer-based hypernetworks into latent variable models. Unlike prior approaches that rely on MLP-based hypernetworks with…

Machine Learning · Computer Science 2025-11-04 Ignacio Peis , Batuhan Koyuncu , Isabel Valera , Jes Frellsen

Machine learning in drug discovery has been focused on virtual screening of molecular libraries using discriminative models. Generative models are an entirely different approach that learn to represent and optimize molecules in a continuous…

Quantitative Methods · Quantitative Biology 2020-11-17 Matthew Ragoza , Tomohide Masuda , David Ryan Koes

Deep learning has been the engine powering many successes of data science. However, the deep neural network (DNN), as the basic model of deep learning, is often excessively over-parameterized, causing many difficulties in training,…

Machine Learning · Statistics 2021-03-09 Yan Sun , Qifan Song , Faming Liang