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Biological sequence design (DNA, RNA, or peptides) with desired functional properties has applications in discovering novel nanomaterials, biosensors, antimicrobial drugs, and beyond. One common challenge is the ability to optimize complex…

Quantitative Methods · Quantitative Biology 2025-12-17 Elham Sadeghi , Xianqi Deng , I-Hsin Lin , Stacy M. Copp , Petko Bogdanov

Variational autoencoders (VAEs) provide an effective and simple method for modeling complex distributions. However, training VAEs often requires considerable hyperparameter tuning to determine the optimal amount of information retained by…

Machine Learning · Computer Science 2021-07-13 Oleh Rybkin , Kostas Daniilidis , Sergey Levine

Variational auto-encoders (VAEs) are a popular and powerful deep generative model. Previous works on VAEs have assumed a factorized likelihood model, whereby the output uncertainty of each pixel is assumed to be independent. This…

Machine Learning · Statistics 2026-05-14 Gara Dorta , Sara Vicente , Lourdes Agapito , Neill D. F. Campbell , Ivor Simpson

Variational Autoencoders are one of the most commonly used generative models, particularly for image data. A prominent difficulty in training VAEs is data that is supported on a lower-dimensional manifold. Recent work by Dai and Wipf (2020)…

Machine Learning · Computer Science 2022-05-19 Frederic Koehler , Viraj Mehta , Chenghui Zhou , Andrej Risteski

Learning disentanglement aims at finding a low dimensional representation which consists of multiple explanatory and generative factors of the observational data. The framework of variational autoencoder (VAE) is commonly used to…

Machine Learning · Computer Science 2023-12-20 Mengyue Yang , Furui Liu , Zhitang Chen , Xinwei Shen , Jianye Hao , Jun Wang

Recently there has been an increased interest in unsupervised learning of disentangled representations using the Variational Autoencoder (VAE) framework. Most of the existing work has focused largely on modifying the variational cost…

Machine Learning · Statistics 2019-09-12 Jan Stühmer , Richard E. Turner , Sebastian Nowozin

This paper introduces the Descriptive Variational Autoencoder (DVAE), an unsupervised and end-to-end trainable neural network for predicting vehicle trajectories that provides partial interpretability. The novel approach is based on the…

Machine Learning · Computer Science 2021-06-25 Marion Neumeier , Andreas Tollkühn , Thomas Berberich , Michael Botsch

Advances in latent diffusion models (LDMs) have revolutionized high-resolution image generation, but the design space of the autoencoder that is central to these systems remains underexplored. In this paper, we introduce LiteVAE, a new…

Machine Learning · Computer Science 2025-01-22 Seyedmorteza Sadat , Jakob Buhmann , Derek Bradley , Otmar Hilliges , Romann M. Weber

This paper presents an infinite variational autoencoder (VAE) whose capacity adapts to suit the input data. This is achieved using a mixture model where the mixing coefficients are modeled by a Dirichlet process, allowing us to integrate…

Machine Learning · Computer Science 2016-11-28 Ehsan Abbasnejad , Anthony Dick , Anton van den Hengel

Handling missing data remains a fundamental challenge in real-world tabular datasets, especially when data are heterogeneous with both numerical and categorical features. Existing imputation methods often fail to capture complex structural…

Machine Learning · Computer Science 2025-12-01 Youran Zhou , Mohamed Reda Bouadjenek , Sunil Aryal%

Latent confounders are a fundamental challenge for inferring causal effects from observational data. The instrumental variable (IV) approach is a practical way to address this challenge. Existing IV based estimators need a known IV or other…

Machine Learning · Computer Science 2024-12-09 Debo Cheng , Jiuyong Li , Lin Liu , Ziqi Xu , Weijia Zhang , Jixue Liu , Thuc Duy Le

We demonstrate the application of machine learning for rapid and accurate extraction of plasmonic particles cluster geometries from hyperspectral image data via a dual variational autoencoder (dual-VAE). In this approach, the information is…

Disordered Systems and Neural Networks · Physics 2022-08-09 Muammer Y. Yaman , Sergei V. Kalinin , Kathryn N. Guye , David Ginger , Maxim Ziatdinov

The discovery of novel materials with tailored electronic properties is crucial for modern device technologies, but time-consuming empirical methods hamper progress. We present an inverse design framework combining an enhanced Wasserstein…

Materials Science · Physics 2025-03-11 Danial Ebrahimzadeh , Sarah S. Sharif , Yaser M. Banad

One major challenge of disentanglement learning with variational autoencoders is the trade-off between disentanglement and reconstruction fidelity. Previous studies, which increase the information bottleneck during training, tend to lose…

Machine Learning · Computer Science 2023-10-05 Jiantao Wu , Shentong Mo , Xiang Yang , Muhammad Awais , Sara Atito , Xingshen Zhang , Lin Wang , Xiang Yang

We develop data-driven methods for incorporating physical information for priors to learn parsimonious representations of nonlinear systems arising from parameterized PDEs and mechanics. Our approach is based on Variational Autoencoders…

Machine Learning · Computer Science 2021-03-17 Ryan Lopez , Paul J. Atzberger

Is there really much more to say about sparse autoencoders (SAEs)? Autoencoders in general, and SAEs in particular, represent deep architectures that are capable of modeling low-dimensional latent structure in data. Such structure could…

Machine Learning · Computer Science 2025-06-09 Yin Lu , Xuening Zhu , Tong He , David Wipf

This work presents an analysis of the hidden representations of Variational Autoencoders (VAEs) using the Intrinsic Dimension (ID) and the Information Imbalance (II). We show that VAEs undergo a transition in behaviour once the bottleneck…

Machine Learning · Computer Science 2024-11-05 Charles Camboulin , Diego Doimo , Aldo Glielmo

We present an autoencoder that leverages learned representations to better measure similarities in data space. By combining a variational autoencoder with a generative adversarial network we can use learned feature representations in the…

Machine Learning · Computer Science 2016-02-12 Anders Boesen Lindbo Larsen , Søren Kaae Sønderby , Hugo Larochelle , Ole Winther

Recently generative models have focused on combining the advantages of variational autoencoders (VAE) and generative adversarial networks (GAN) for good reconstruction and generative abilities. In this work we introduce a novel hybrid…

Machine Learning · Computer Science 2019-10-01 Prateek Munjal , Akanksha Paul , Narayanan C. Krishnan

People can easily imagine the potential sound while seeing an event. This natural synchronization between audio and visual signals reveals their intrinsic correlations. To this end, we propose to learn the audio-visual correlations from the…

Computer Vision and Pattern Recognition · Computer Science 2021-02-16 Ye Zhu , Yu Wu , Hugo Latapie , Yi Yang , Yan Yan
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