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In routine colorectal cancer management, histologic samples stained with hematoxylin and eosin are commonly used. Nonetheless, their potential for defining objective biomarkers for patient stratification and treatment selection is still…

Quantitative Methods · Quantitative Biology 2024-09-26 Fabi Prezja , Leevi Annala , Sampsa Kiiskinen , Suvi Lahtinen , Timo Ojala , Pekka Ruusuvuori , Teijo Kuopio

Image quality plays a big role in CNN-based image classification performance. Fine-tuning the network with distorted samples may be too costly for large networks. To solve this issue, we propose a transfer learning approach optimized to…

Computer Vision and Pattern Recognition · Computer Science 2019-06-04 Alessandro Bianchi , Moreno Raimondo Vendra , Pavlos Protopapas , Marco Brambilla

Deep convolutional neural networks (CNNs) can be applied to malware binary detection via image classification. The performance, however, is degraded due to the imbalance of malware families (classes). To mitigate this issue, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2022-02-22 Songqing Yue , Tianyang Wang

The output of Convolutional Neural Networks (CNN) has been shown to be discontinuous which can make the CNN image classifier vulnerable to small well-tuned artificial perturbations. That is, images modified by adding such perturbations(i.e.…

Computer Vision and Pattern Recognition · Computer Science 2018-04-20 Jiawei Su , Danilo Vasconcellos Vargas , Kouichi Sakurai

Modern cosmological research in large scale structure has witnessed an increasing number of applications of machine learning methods. Among them, Convolutional Neural Networks (CNNs) have received substantial attention due to their…

Cosmology and Nongalactic Astrophysics · Physics 2024-02-16 Zhengyangguang Gong , Anik Halder , Annabelle Bohrdt , Stella Seitz , David Gebauer

Mutation analysis of deep neural networks (DNNs) is a promising method for effective evaluation of test data quality and model robustness, but it can be computationally expensive, especially for large models. To alleviate this, we present…

Software Engineering · Computer Science 2025-01-23 Lauren Lyons , Ali Ghanbari

Convolutional Neural Networks (CNNs) have achieved remarkable success across a wide range of machine learning tasks by leveraging hierarchical feature learning through deep architectures. However, the large number of layers and millions of…

Machine Learning · Statistics 2025-11-18 Biyi Fang , Truong Vo , Jean Utke , Diego Klabjan

The success of convolution neural networks (CNN) has been revolutionising the way we approach and use intelligent machines in the Big Data era. Despite success, CNNs have been consistently put under scrutiny owing to their…

Computer Vision and Pattern Recognition · Computer Science 2022-10-18 Shengxi Li , Xinyi Zhao , Ljubisa Stankovic , Danilo Mandic

Stain variation is a phenomenon observed when distinct pathology laboratories stain tissue slides that exhibit similar but not identical color appearance. Due to this color shift between laboratories, convolutional neural networks (CNNs)…

Computer Vision and Pattern Recognition · Computer Science 2020-04-16 David Tellez , Geert Litjens , Peter Bandi , Wouter Bulten , John-Melle Bokhorst , Francesco Ciompi , Jeroen van der Laak

This technical report presents research results achieved in the field of verification of trained Convolutional Neural Network (CNN) used for image classification in safety-critical applications. As running example, we use the obstacle…

Computer Vision and Pattern Recognition · Computer Science 2024-01-15 Jan Peleska , Felix Brüning , Mario Gleirscher , Wen-ling Huang

Automated methods for breast cancer detection have focused on 2D mammography and have largely ignored 3D digital breast tomosynthesis (DBT), which is frequently used in clinical practice. The two key challenges in developing automated…

Computer Vision and Pattern Recognition · Computer Science 2020-02-28 Yu Zhang , Xiaoqin Wang , Hunter Blanton , Gongbo Liang , Xin Xing , Nathan Jacobs

Convolution Neural Networks (CNNs) are widely used in medical image analysis, but their performance degrade when the magnification of testing images differ from the training images. The inability of CNNs to generalize across magnification…

Image and Video Processing · Electrical Eng. & Systems 2023-02-23 Pranav Jeevan , Nikhil Cherian Kurian , Amit Sethi

Convolutional Neural Network is good at image classification. However, it is found to be vulnerable to image quality degradation. Even a small amount of distortion such as noise or blur can severely hamper the performance of these CNN…

Computer Vision and Pattern Recognition · Computer Science 2020-08-07 Md Tahmid Hossain , Shyh Wei Teng , Dengsheng Zhang , Suryani Lim , Guojun Lu

During the last decade, deep neural networks (DNN) have demonstrated impressive performances solving a wide range of problems in various domains such as medicine, finance, law, etc. Despite their great performances, they have long been…

Machine Learning · Computer Science 2020-10-13 Jiechieu Kameni Florentin Flambeau , Tsopze Norbert

Micro Abstract: A recent study from GLOBOCAN disclosed that during 2018 two million women worldwide had been diagnosed from breast cancer. This study presents a computer-aided diagnosis system based on convolutional neural networks as an…

Computer Vision and Pattern Recognition · Computer Science 2019-10-31 Juan Zuluaga-Gomez , Zeina Al Masry , Khaled Benaggoune , Safa Meraghni , Noureddine Zerhouni

Deep Neural Networks (DNN) and especially Convolutional Neural Networks (CNN) are a de-facto standard for the analysis of large volumes of signals and images. Yet, their development and underlying principles have been largely performed in…

Information Theory · Computer Science 2022-03-24 Ljubisa Stankovic , Danilo Mandic

Computer assisted diagnosis in digital pathology is becoming ubiquitous as it can provide more efficient and objective healthcare diagnostics. Recent advances have shown that the convolutional Neural Network (CNN) architectures, a…

Image and Video Processing · Electrical Eng. & Systems 2022-01-05 Sruthi Krishna , Suganthi S. S , Shivsubramani Krishnamoorthy , Arnav Bhavsar

In this paper we describe the implementation of a convolutional neural network (CNN) used to assess online review helpfulness. To our knowledge, this is the first use of this architecture to address this problem. We explore the impact of…

Computer Vision and Pattern Recognition · Computer Science 2018-08-29 Xianshan Qu , Xiaopeng Li , John R. Rose

Convolutional Neural Networks have played a significant role in various medical imaging tasks like classification and segmentation. They provide state-of-the-art performance compared to classical image processing algorithms. However, the…

Computer Vision and Pattern Recognition · Computer Science 2022-10-03 Rakshith Sathish , Swanand Khare , Debdoot Sheet

One of the main challenges for broad adoption of deep learning based models such as convolutional neural networks (CNN), is the lack of understanding of their decisions. In many applications, a simpler, less capable model that can be easily…

Computer Vision and Pattern Recognition · Computer Science 2018-02-08 Devinder Kumar , Vlado Menkovski , Graham W. Taylor , Alexander Wong