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The Ideal Observer (IO) performance has been advocated when optimizing medical imaging systems for signal detection tasks. However, analytical computation of the IO test statistic is generally intractable. To approximate the IO test…

Signal Processing · Electrical Eng. & Systems 2020-01-28 Weimin Zhou , Mark A. Anastasio

The ideal observer (IO) sets an upper performance limit among all observers and has been advocated for assessing and optimizing imaging systems. For general joint detection and estimation (detection-estimation) tasks, estimation ROC (EROC)…

Signal Processing · Electrical Eng. & Systems 2021-12-03 Kaiyan Li , Weimin Zhou , Hua Li , Mark A. Anastasio

In medical imaging, it is widely recognized that image quality should be objectively evaluated based on performance in clinical tasks. To evaluate performance in signal-detection tasks, the ideal observer (IO) is optimal but also…

Medical Physics · Physics 2022-03-09 Md Ashequr Rahman , Zitong Yu , Abhinav K. Jha

Medical imaging systems are commonly assessed and optimized by use of objective measures of image quality (IQ). The Ideal Observer (IO) performance has been advocated to provide a figure-of-merit for use in assessing and optimizing imaging…

Signal Processing · Electrical Eng. & Systems 2020-07-16 Weimin Zhou , Hua Li , Mark A. Anastasio

It is widely accepted that optimization of medical imaging system performance should be guided by task-based measures of image quality (IQ). Task-based measures of IQ quantify the ability of an observer to perform a specific task such as…

Signal Processing · Electrical Eng. & Systems 2019-05-17 Weimin Zhou , Hua Li , Mark A. Anastasio

Medical imaging systems are commonly assessed and optimized by the use of objective measures of image quality (IQ). The performance of the ideal observer (IO) acting on imaging measurements has long been advocated as a figure-of-merit to…

Medical Physics · Physics 2025-01-17 Kaiyan Li , Prabhat Kc , Hua Li , Kyle J. Myers , Mark A. Anastasio , Rongping Zeng

Task-based assessment of image quality (IQ) is critically important for the design and optimization of medical imaging systems. Ideal observers, including the Bayesian Ideal Observer (IO) and the ideal linear observer, i.e., the Hotelling…

Image and Video Processing · Electrical Eng. & Systems 2026-05-29 Weimin Zhou

Purpose: To objectively assess new medical imaging technologies via computer-simulations, it is important to account for the variability in the ensemble of objects to be imaged. This source of variability can be described by stochastic…

Image and Video Processing · Electrical Eng. & Systems 2022-03-01 Weimin Zhou , Sayantan Bhadra , Frank J. Brooks , Hua Li , Mark A. Anastasio

It is widely accepted that the Bayesian ideal observer (IO) should be used to guide the objective assessment and optimization of medical imaging systems. The IO employs complete task-specific information to compute test statistics for…

Signal Processing · Electrical Eng. & Systems 2025-02-03 Weimin Zhou

Generative artificial intelligence (AI) has made unprecedented advances in vision language models over the past two years. During the generative process, new samples (images) are generated from an unknown high-dimensional distribution.…

Graphics · Computer Science 2025-10-13 Gurprit Singh , Wenzel Jakob

Statistical signal processing applications usually require the estimation of some parameters of interest given a set of observed data. These estimates are typically obtained either by solving a multi-variate optimization problem, as in the…

Computation · Statistics 2021-07-27 D. Luengo , L. Martino , M. Bugallo , V. Elvira , S. Särkkä

Monte Carlo (MC) methods are widely used for Bayesian inference and optimization in statistics, signal processing and machine learning. A well-known class of MC methods are Markov Chain Monte Carlo (MCMC) algorithms. In order to foster…

Computation · Statistics 2016-09-27 L. Martino , V. Elvira , D. Luengo , J. Corander , F. Louzada

Markov chain Monte Carlo (MCMC) is a powerful tool for sampling from complex probability distributions. Despite its versatility, MCMC often suffers from strong autocorrelation and the negative sign problem, leading to slowing down the…

Statistical Mechanics · Physics 2024-12-05 Synge Todo

In many hierarchical inverse problems, not only do we want to estimate high- or infinite-dimensional model parameters in the parameter-to-observable maps, but we also have to estimate hyperparameters that represent critical assumptions in…

Computation · Statistics 2020-02-18 Johnathan Bardsley , Tiangang Cui

It has been advocated that medical imaging systems and reconstruction algorithms should be assessed and optimized by use of objective measures of image quality that quantify the performance of an observer at specific diagnostic tasks. One…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Weimin Zhou , Sayantan Bhadra , Frank J. Brooks , Hua Li , Mark A. Anastasio

In this article we consider Bayesian estimation of static parameters for a class of partially observed McKean-Vlasov diffusion processes with discrete-time observations over a fixed time interval. This problem features several obstacles to…

Computation · Statistics 2025-04-23 Ajay Jasra , Amin Wu

We consider the efficient use of an approximation within Markov chain Monte Carlo (MCMC), with subsequent importance sampling (IS) correction of the Markov chain inexact output, leading to asymptotically exact inference. We detail…

Computation · Statistics 2019-04-15 Jordan Franks

Markov Chain Monte Carlo (MCMC) methods sample from unnormalized probability distributions and offer guarantees of exact sampling. However, in the continuous case, unfavorable geometry of the target distribution can greatly limit the…

Machine Learning · Statistics 2020-10-09 Zengyi Li , Yubei Chen , Friedrich T. Sommer

Generative adversarial networks (GANs) have emerged as a powerful tool for generating high-fidelity data. However, the main bottleneck of existing approaches is the lack of supervision on the generator training, which often results in…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Baoren Xiao , Hao Ni , Weixin Yang

In the context of solving inverse problems for physics applications within a Bayesian framework, we present a new approach, Markov Chain Generative Adversarial Neural Networks (MCGANs), to alleviate the computational costs associated with…

Numerical Analysis · Mathematics 2022-09-08 Nikolaj T. Mücke , Benjamin Sanderse , Sander Bohté , Cornelis W. Oosterlee
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