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We introduce and analyze a purely competitive dynamics for the evolution of an infinite population subject to a 3-strategy game. We argue that this dynamics represents a characterization of how certain systems, both natural and artificial,…

Populations and Evolution · Quantitative Biology 2012-12-12 Carl Veller , Vinesh Rajpaul

In evolutionary dynamics, a key measure of a mutant trait's success is the probability that it takes over the population given some initial mutant-appearance distribution. This "fixation probability" is difficult to compute in general, as…

Populations and Evolution · Quantitative Biology 2022-02-18 Alex McAvoy , Benjamin Allen

To understand the effect of assortative mating on the genetic evolution of a population, we consider a finite population in which each individual has a type, determined by a sequence of n diallelic loci. We assume that the population…

Probability · Mathematics 2023-11-30 Alison M. Etheridge , Sophie Lemaire

We study the population genetics of two neutral alleles under reversible mutation in the \Lambda-processes, a population model that features a skewed offspring distribution. We describe the shape of the equilibrium allele frequency…

Populations and Evolution · Quantitative Biology 2013-06-21 Ricky Der , Joshua B. Plotkin

We explore the interaction between two genetic incompatibilities (underdominant loci in diploid organisms) in a population occupying a one-dimensional space. We derive a system of partial differential equations describing the dynamics of…

Analysis of PDEs · Mathematics 2021-04-08 Matthieu Alfaro , Quentin Griette , Denis Roze , Benoît Sarels

Large populations may contain numerous simultaneously segregating polymorphisms subject to natural selection. Since selection acts on individuals whose fitness depends on many loci, different loci affect each other's dynamics. This leads to…

Populations and Evolution · Quantitative Biology 2011-08-09 Richard A. Neher , Boris I. Shraiman

A steady influx of a single deleterious multilocus genotype will impose genetic load on the resident population and leave multiple descendants carrying various numbers of the foreign alleles. Provided that the foreign types are rare at…

Populations and Evolution · Quantitative Biology 2015-06-16 Alexey Yanchukov , Stephen R. Proulx

We deal with the study of the evolution of the allelic frequencies, at a single locus, for a population distributed continuously over a bounded habitat. We consider evolution which occurs under the joint action of selection and arbitrary…

Analysis of PDEs · Mathematics 2017-01-27 Elisa Sovrano

Species diversity in ecosystems is often accompanied by the self-organisation of the population into fascinating spatio-temporal patterns. Here, we consider a two-dimensional three-species population model and study the spiralling patterns…

Populations and Evolution · Quantitative Biology 2013-05-09 Bartosz Szczesny , Mauro Mobilia , Alastair M. Rucklidge

We introduce a multi-allele Wright-Fisher model with non-recurrent, reversible mutation and directional selection. In this setting, the allele frequencies at a single locus track the path of a hybrid jump-diffusion process with state space…

Probability · Mathematics 2023-02-16 Ingemar Kaj , Carina F. Mugal , Rebekka Müller

Biochemical and regulatory interactions central to biological networks are expected to cause extensive genetic interactions or epistasis affecting the heritability of complex traits and the distribution of genotypes in populations. However,…

Populations and Evolution · Quantitative Biology 2009-12-15 Richard A. Neher , Boris I. Shraiman

In sexual populations, selection operates neither on the whole genome, which is repeatedly taken apart and reassembled by recombination, nor on individual alleles that are tightly linked to the chromosomal neighborhood. The resulting…

Populations and Evolution · Quantitative Biology 2014-03-25 Richard A. Neher , Taylor A. Kessinger , Boris I. Shraiman

Weak purifying selection, acting on many linked mutations, may play a major role in shaping patterns of molecular evolution in natural populations. Yet efforts to infer these effects from DNA sequence data are limited by our incomplete…

Populations and Evolution · Quantitative Biology 2012-10-17 Benjamin H Good , Michael M Desai

The evolution of genetic systems has been analyzed through the use of modifier gene models, in which a neutral gene is posited to control the transmission of other genes under selection. Analysis of modifier gene models has found the…

Populations and Evolution · Quantitative Biology 2013-02-04 Lee Altenberg

The dynamics of a population undergoing selection is a central topic in evolutionary biology. This question is particularly intriguing in the case where selective forces act in opposing directions at two population scales. For example, a…

Probability · Mathematics 2017-05-03 Shishi Luo , Jonathan C. Mattingly

We consider an infinitely large population under stabilising selection and mutation in which the allelic effects determining a polygenic trait vary between loci. We obtain analytical expressions for the stationary genetic variance as a…

Populations and Evolution · Quantitative Biology 2016-01-13 Kavita Jain , Wolfgang Stephan

In this paper we introduce a multilocus diffusion model of a population of $N$ haploid, asexually reproducing individuals. The model includes parent-dependent mutation and interlocus selection, the latter limited to pairwise relationships…

Probability · Mathematics 2019-12-16 Erik Aurell , Magnus Ekeberg , Timo Koski

Selection, mutation and random drift affect the dynamics of allele frequencies and consequently of quantitative traits. While the macroscopic dynamics of quantitative traits can be measured, the underlying allele frequencies are typically…

Populations and Evolution · Quantitative Biology 2016-03-15 Katarína Boďová , Gašper Tkačik , Nicholas H. Barton

We study a variant of the cyclic Lotka-Volterra model with three-agent interactions. Inspired by a multiplayer variation of the Rock-Paper-Scissors game, the model describes an ideal ecosystem in which cyclic competition among three species…

Populations and Evolution · Quantitative Biology 2020-10-09 Filippo Palombi , Stefano Ferriani , Simona Toti

Fixation probabilities are essential for characterizing stochastic evolutionary dynamics, but analytical results remain limited mainly to systems with two competing types. We develop a perturbative framework to compute fixation…

Populations and Evolution · Quantitative Biology 2026-04-15 Ian Braga , Lucas Wardil , Ricardo Martinez-Garcia