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We consider the problem of variable selection in high-dimensional settings with missing observations among the covariates. To address this relatively understudied problem, we propose a new synergistic procedure -- adaptive Bayesian SLOPE --…

Survival analysis is a widely-used technique for analyzing time-to-event data in the presence of censoring. In recent years, numerous survival analysis methods have emerged which scale to large datasets and relax traditional assumptions…

Machine Learning · Computer Science 2023-11-06 Mert Ketenci , Shreyas Bhave , Noémie Elhadad , Adler Perotte

High dimensional and heterogeneous count data are collected in various applied fields. In this paper, we look closely at high-resolution sequencing data on the microbiome, which have enabled researchers to study the genomes of entire…

Methodology · Statistics 2024-01-12 Veronica Vinciotti , Pariya Behrouzi , Reza Mohammadi

In a broad range of classification and decision making problems, one is given the advice or predictions of several classifiers, of unknown reliability, over multiple questions or queries. This scenario is different from the standard…

Machine Learning · Statistics 2014-02-07 Fabio Parisi , Francesco Strino , Boaz Nadler , Yuval Kluger

Similarity-driven multi-view linear reconstruction (SiMLR) is an algorithm that exploits inter-modality relationships to transform large scientific datasets into smaller, more well-powered and interpretable low-dimensional spaces. SiMLR…

Machine Learning · Statistics 2021-01-22 Brian B. Avants , Nicholas J. Tustison , James R. Stone

Modeling dynamical biological systems is key for understanding, predicting, and controlling complex biological behaviors. Traditional methods for identifying governing equations, such as ordinary differential equations (ODEs), typically…

Molecular Networks · Quantitative Biology 2024-12-23 Hanna Krasowski , Eric Palanques-Tost , Calin Belta , Murat Arcak

The generalized Lotka-Volterra (gLV) equations are a mathematical proxy for ecological dynamics. We focus on a gLV model of the gut microbiome, in which the evolution of the gut microbial state is determined in part by pairwise…

Populations and Evolution · Quantitative Biology 2020-05-13 Zipeng Wang , Eric W. Jones , Joshua M. Mueller , Jean M. Carlson

As a popular tool for producing meaningful and interpretable models, large-scale sparse learning works efficiently when the underlying structures are indeed or close to sparse. However, naively applying the existing regularization methods…

Methodology · Statistics 2017-10-10 Zemin Zheng , Jinchi Lv , Wei Lin

We consider the problems of variable selection and estimation in nonparametric additive regression models for high-dimensional data. In recent years, several methods have been proposed to model nonlinear relationships when the number of…

Methodology · Statistics 2013-10-07 Linn Cecilie Bergersen , Kukatharmini Tharmaratnam , Ingrid K. Glad

This research paper investigates the effectiveness of simple linear models versus complex machine learning techniques in breast cancer diagnosis, emphasizing the importance of interpretability and computational efficiency in the medical…

Machine Learning · Computer Science 2023-06-06 Muhammad Arbab Arshad , Sakib Shahriar , Khizar Anjum

Similar to variable selection in the linear regression model, selecting significant components in the popular additive regression model is of great interest. However, such components are unknown smooth functions of independent variables,…

Methodology · Statistics 2011-01-04 Xia Cui , Heng Peng , Songqiao Wen , Lixing Zhu

We present a novel method for symbolic regression (SR), the task of searching for compact programmatic hypotheses that best explain a dataset. The problem is commonly solved using genetic algorithms; we show that we can enhance such methods…

Machine Learning · Computer Science 2024-12-11 Arya Grayeli , Atharva Sehgal , Omar Costilla-Reyes , Miles Cranmer , Swarat Chaudhuri

High accuracy in cancer prediction is important to improve the quality of the treatment and to improve the rate of survivability of patients. As the data volume is increasing rapidly in the healthcare research, the analytical challenge…

Machine Learning · Computer Science 2014-03-13 J S Saleema , N Bhagawathi , S Monica , P Deepa Shenoy , K R Venugopal , L M Patnaik

Among the most popular variable selection procedures in high-dimensional regression, Lasso provides a solution path to rank the variables and determines a cut-off position on the path to select variables and estimate coefficients. In this…

Methodology · Statistics 2018-06-19 X. Jessie Jeng , Huimin Peng , Wenbin Lu

Computational pathology models that use digitized histopathology whole-slide images have the potential to become a cost-effective and scalable alternative to molecular assays for the prediction of genomic biomarkers, a key task in precision…

Quantitative Methods · Quantitative Biology 2026-03-03 Ekaterina Redekop , Eric Zimmermann , Ava P Amini , Alex X Lu , Neil Tenenholtz , James Brian Hall , Lorin Crawford , Kristen A Severson

In supervised machine learning, feature selection plays a very important role by potentially enhancing explainability and performance as measured by computing time and accuracy-related metrics. In this paper, we investigate a method for…

Machine Learning · Computer Science 2024-02-02 Raisa Islam , Subhasish Mazumdar , Rakibul Islam

Multi-label classification studies the task where each example belongs to multiple labels simultaneously. As a representative method, Ranking Support Vector Machine (Rank-SVM) aims to minimize the Ranking Loss and can also mitigate the…

Machine Learning · Computer Science 2019-11-06 Guoqiang Wu , Ruobing Zheng , Yingjie Tian , Dalian Liu

Hazard ratios are frequently reported in time-to-event and epidemiological studies to assess treatment effects. In observational studies, the combination of propensity score weights with the Cox proportional hazards model facilitates the…

Methodology · Statistics 2024-02-14 Guilherme W. F. Barros , Jenny Häggström

Adapting pre-trained models to new tasks can exhibit varying effectiveness across datasets. Visual prompting, a state-of-the-art parameter-efficient transfer learning method, can significantly improve the performance of out-of-distribution…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Hsi-Ai Tsao , Lei Hsiung , Pin-Yu Chen , Tsung-Yi Ho

Nowadays Big Data are becoming more and more important. Many sectors of our economy are now guided by data-driven decision processes. Big Data and business intelligence applications are facilitated by the MapReduce programming model while,…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-12-06 Alessandro Maria Rizzi