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A Bayesian feature allocation model (FAM) is presented for identifying cell subpopulations based on multiple samples of cell surface or intracellular marker expression level data obtained by cytometry by time of flight (CyTOF). Cell…

Applications · Statistics 2020-02-21 Arthur Lui , Juhee Lee , Peter F. Thall , May Daher , Katy Rezvani , Rafet Barar

A well-known issue of Batch Normalization is its significantly reduced effectiveness in the case of small mini-batch sizes. When a mini-batch contains few examples, the statistics upon which the normalization is defined cannot be reliably…

Machine Learning · Computer Science 2021-03-26 Zhuliang Yao , Yue Cao , Shuxin Zheng , Gao Huang , Stephen Lin

Graph neural networks (GNNs) have been proposed for medical image segmentation, by predicting anatomical structures represented by graphs of vertices and edges. One such type of graph is predefined with fixed size and connectivity to…

Image and Video Processing · Electrical Eng. & Systems 2023-03-20 Qian Li , Yunguan Fu , Qianye Yang , Zhijiang Du , Hongjian Yu , Yipeng Hu

Batch normalization (BN) uniformly shifts and scales the activations based on the statistics of a batch of images. However, the intensity distribution of the background pixels often dominates the BN statistics because the background…

Image and Video Processing · Electrical Eng. & Systems 2022-08-08 Junfei Xiao , Lequan Yu , Zongwei Zhou , Yutong Bai , Lei Xing , Alan Yuille , Yuyin Zhou

This paper introduces a novel network topology that seamlessly integrates dynamic inference cost with a top-down attention mechanism, addressing two significant gaps in traditional deep learning models. Drawing inspiration from human…

Computer Vision and Pattern Recognition · Computer Science 2024-11-21 André Peter Kelm , Niels Hannemann , Bruno Heberle , Lucas Schmidt , Tim Rolff , Christian Wilms , Ehsan Yaghoubi , Simone Frintrop

Localization in topological maps is essential for image-based navigation using an RGB camera. Localization using only one camera can be challenging in medium-to-large-sized environments because similar-looking images are often observed…

Robotics · Computer Science 2022-04-29 Takahiro Niwa , Shun Taguchi , Noriaki Hirose

The international neuroscience community is building the first comprehensive atlases of brain cell types to understand how the brain functions from a higher resolution, and more integrated perspective than ever before. In order to build…

Neurons and Cognition · Quantitative Biology 2023-08-03 Thomas L. Athey , Daniel J. Tward , Ulrich Mueller , Laurent Younes , Joshua T. Vogelstein , Michael I. Miller

Nuclei classification is a critical step in computer-aided diagnosis with histopathology images. In the past, various methods have employed graph neural networks (GNN) to analyze cell graphs that model inter-cell relationships by…

Computer Vision and Pattern Recognition · Computer Science 2024-02-21 Wei Lou , Guanbin Li , Xiang Wan , Haofeng Li

Quantized Neural Networks (QNNs) use low bit-width fixed-point numbers for representing weight parameters and activations, and are often used in real-world applications due to their saving of computation resources and reproducibility of…

Machine Learning · Computer Science 2020-09-01 Dachao Lin , Peiqin Sun , Guangzeng Xie , Shuchang Zhou , Zhihua Zhang

For data sampled from an arbitrary density on a manifold embedded in Euclidean space, the Continuous k-Nearest Neighbors (CkNN) graph construction is introduced. It is shown that CkNN is geometrically consistent in the sense that under…

Classical Analysis and ODEs · Mathematics 2019-02-26 Tyrus Berry , Timothy Sauer

Human brain atlases provide spatial reference systems for data characterizing brain organization at different levels, coming from different brains. Cytoarchitecture is a basic principle of the microstructural organization of the brain, as…

Image and Video Processing · Electrical Eng. & Systems 2021-07-07 Christian Schiffer , Hannah Spitzer , Kai Kiwitz , Nina Unger , Konrad Wagstyl , Alan C. Evans , Stefan Harmeling , Katrin Amunts , Timo Dickscheid

The automated analysis of flow cytometry measurements is an active research field. We introduce a new algorithm, referred to as CytOpT, using regularized optimal transport to directly estimate the different cell population proportions from…

Applications · Statistics 2022-07-01 Paul Freulon , Jérémie Bigot , Boris P. Hejblum

Residual connections and normalization layers have become standard design choices for graph neural networks (GNNs), and were proposed as solutions to the mitigate the oversmoothing problem in GNNs. However, how exactly these methods help…

Machine Learning · Computer Science 2026-01-21 Michael Scholkemper , Xinyi Wu , Ali Jadbabaie , Michael T. Schaub

Deep neural networks have useful applications in many different tasks, however their performance can be severely affected by changes in the data distribution. For example, in the biomedical field, their performance can be affected by…

Computer Vision and Pattern Recognition · Computer Science 2024-05-30 Pedro Vianna , Muawiz Chaudhary , Paria Mehrbod , An Tang , Guy Cloutier , Guy Wolf , Michael Eickenberg , Eugene Belilovsky

To address the issue of catastrophic forgetting in neural networks, we propose a novel, simple, and effective solution called neuron-level plasticity control (NPC). While learning a new task, the proposed method preserves the knowledge for…

Computer Vision and Pattern Recognition · Computer Science 2019-08-01 Inyoung Paik , Sangjun Oh , Tae-Yeong Kwak , Injung Kim

A connectional brain template (CBT) is a normalized graph-based representation of a population of brain networks also regarded as an average connectome. CBTs are powerful tools for creating representative maps of brain connectivity in…

Computer Vision and Pattern Recognition · Computer Science 2020-12-29 Mustafa Burak Gurbuz , Islem Rekik

The accurate segmentation and tracking of cells in microscopy image sequences is an important task in biomedical research, e.g., for studying the development of tissues, organs or entire organisms. However, the segmentation of touching…

Computer Vision and Pattern Recognition · Computer Science 2020-12-10 Tim Scherr , Katharina Löffler , Moritz Böhland , Ralf Mikut

Training state-of-the-art, deep neural networks is computationally expensive. One way to reduce the training time is to normalize the activities of the neurons. A recently introduced technique called batch normalization uses the…

Machine Learning · Statistics 2016-07-22 Jimmy Lei Ba , Jamie Ryan Kiros , Geoffrey E. Hinton

Histopathology image synthesis aims to address the data shortage issue in training deep learning approaches for accurate cancer detection. However, existing methods struggle to produce realistic images that have accurate nuclei boundaries…

Image and Video Processing · Electrical Eng. & Systems 2023-01-25 Sujata Butte , Haotian Wang , Aleksandar Vakanski , Min Xian

We present a novel graph-based approach for labeling the anatomical branches of a given airway tree segmentation. The proposed method formulates airway labeling as a branch classification problem in the airway tree graph, where branch…

Computer Vision and Pattern Recognition · Computer Science 2022-01-13 Weiyi Xie , Colin Jacobs , Jean-Paul Charbonnier , Bram van Ginneken
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