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The success of machine learning models relies heavily on effectively representing high-dimensional data. However, ensuring data representations capture human-understandable concepts remains difficult, often requiring the incorporation of…

Machine Learning · Statistics 2024-11-01 Jiayu Su , David A. Knowles , Raul Rabadan

Current mathematical frameworks for predicting the flux state and macromolecular composition of the cell do not rely on thermodynamic constraints to determine the spontaneous direction of reactions. These predictions may be biologically…

Optimization and Control · Mathematics 2020-08-14 Amir Akbari , Bernhard O. Palsson

The use of principal component methods to analyze functional data is appropriate in a wide range of different settings. In studies of ``functional data analysis,'' it has often been assumed that a sample of random functions is observed…

Statistics Theory · Mathematics 2016-08-16 Peter Hall , Hans-Georg Müller , Jane-Ling Wang

Independent Component Analysis (ICA) was introduced in the 1980's as a model for Blind Source Separation (BSS), which refers to the process of recovering the sources underlying a mixture of signals, with little knowledge about the source…

Statistics Theory · Mathematics 2026-02-09 Syamantak Kumar , Purnamrita Sarkar , Peter Bickel , Derek Bean

The independent component model is a latent variable model where the components of the observed random vector are linear combinations of latent independent variables. The aim is to find an estimate for a transformation matrix back to…

Statistics Theory · Mathematics 2015-05-12 Joni Virta , Klaus Nordhausen , Hannu Oja

We propose new statistical tests, in high-dimensional settings, for testing the independence of two random vectors and their conditional independence given a third random vector. The key idea is simple, i.e., we first transform each…

Methodology · Statistics 2026-01-28 Jinyuan Chang , Yue Du , Jing He , Qiwei Yao

Analysis of high-dimensional data has led to increased interest in both single index models (SIMs) and the best-subset selection. SIMs provide an interpretable and flexible modeling framework for high-dimensional data, while the best-subset…

Machine Learning · Statistics 2025-08-19 Borui Tang , Jin Zhu , Junxian Zhu , Xueqin Wang , Heping Zhang

In this chapter, we discuss recent work on learning sparse approximations to high-dimensional functions on data, where the target functions may be scalar-, vector- or even Hilbert space-valued. Our main objective is to study how the…

Numerical Analysis · Mathematics 2022-02-08 Ben Adcock , Juan M. Cardenas , Nick Dexter , Sebastian Moraga

Extraordinary amounts of data are being produced in many branches of science. Proven statistical methods are no longer applicable with extraordinary large data sets due to computational limitations. A critical step in big data analysis is…

Methodology · Statistics 2019-06-27 HaiYing Wang , Min Yang , John Stufken

Simulation offers a simple and flexible way to estimate the power of a clinical trial when analytic formulae are not available. The computational burden of using simulation has, however, restricted its application to only the simplest of…

We consider independent component analysis of binary data. While fundamental in practice, this case has been much less developed than ICA for continuous data. We start by assuming a linear mixing model in a continuous-valued latent space,…

Machine Learning · Computer Science 2022-08-03 Antti Hyttinen , Vitória Barin-Pacela , Aapo Hyvärinen

An analysis of the protein content of several crystal forms of proteins has been performed. We apply a new numerical technique, the Independent Component Analysis (ICA), to determine the volume fraction of the asymmetric unit occupied by…

Quantitative Methods · Quantitative Biology 2008-12-02 Antonio Lamura , Massimo Ladisa , Giovanni Nico , Dritan Siliqi

Principal Component Analysis (PCA) is an important tool of dimension reduction especially when the dimension (or the number of variables) is very high. Asymptotic studies where the sample size is fixed, and the dimension grows [i.e., High…

Statistics Theory · Mathematics 2009-11-20 Sungkyu Jung , J. S. Marron

Despite broad interest in self-organizing systems, there are few quantitative, experimentally-applicable criteria for self-organization. The existing criteria all give counter-intuitive results for important cases. In this Letter, we…

Adaptation and Self-Organizing Systems · Physics 2011-11-10 Cosma Rohilla Shalizi , Kristina Lisa Shalizi , Robert Haslinger

The problem of estimating the mean of random functions based on discretely sampled data arises naturally in functional data analysis. In this paper, we study optimal estimation of the mean function under both common and independent designs.…

Statistics Theory · Mathematics 2012-02-24 T. Tony Cai , Ming Yuan

This paper investigates a general robust one-shot aggregation framework for distributed and federated Independent Component Analysis (ICA) problem. We propose a geometric median-based aggregation algorithm that leverages $k$-means…

Machine Learning · Computer Science 2025-05-28 Dian Jin , Xin Bing , Yuqian Zhang

Principal component analysis is a useful dimension reduction and data visualization method. However, in high dimension, low sample size asymptotic contexts, where the sample size is fixed and the dimension goes to infinity,a paradox has…

Applications · Statistics 2012-11-21 Dan Shen , Haipeng Shen , Hongtu Zhu , J. S. Marron

We propose an ICA contrast based on the density estimation of the observed signal and its marginals by means of wavelets. The risk of the associated moment estimator is linked with approximation properties in Besov spaces. It is shown to…

Statistics Theory · Mathematics 2007-06-13 Pascal Barbedor

Principal component analysis (PCA) has been widely applied to dimensionality reduction and data pre-processing for different applications in engineering, biology and social science. Classical PCA and its variants seek for linear projections…

Machine Learning · Computer Science 2017-07-11 Xiaojun Chang , Feiping Nie , Yi Yang , Heng Huang

Principal component analysis (PCA) is a classical method for dimensionality reduction based on extracting the dominant eigenvectors of the sample covariance matrix. However, PCA is well known to behave poorly in the ``large $p$, small $n$''…

Statistics Theory · Mathematics 2009-08-26 Arash A. Amini , Martin J. Wainwright
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