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High-brightness X-ray Free Electron Lasers (FELs) produce spatially and temporally coherent pulses on attosecond to femtosecond timescales, providing a transformative tool for discovery across biology, chemistry, physics, and materials…

Accelerator Physics · Physics 2026-03-20 Ji Qiang

X-ray mirrors with high focusing performances are in use in both mirror modules for X-ray telescopes and in synchrotron and FEL (Free Electron Laser) beamlines. A degradation of the focus sharpness arises in general from geometrical…

Optics · Physics 2013-04-05 D. Spiga , L. Raimondi , C. Svetina , M. Zangrando

The core theme of X-ray crystallography is reconstructing the electron density distribution of crystals under the constraints of observed diffraction data. Nevertheless, the reconstruction of electron density distribution by straightforward…

Materials Science · Physics 2015-07-14 Hui Li , Meng He , Ze Zhang

Despite the huge advancement in knowledge discovery and data mining techniques, the X-ray diffraction (XRD) analysis process has mostly remained untouched and still involves manual investigation, comparison, and verification. Due to the…

The phase-field approach to brittle fracture provides a continuum framework for modeling crack initiation and propagation without explicit representation of discrete crack surfaces, provided the spatial discretization is fine enough to…

Computational Engineering, Finance, and Science · Computer Science 2026-03-11 Lucas Hermann , Ralf Jänicke , Knut Andreas Meyer , Ulrich Römer

Dark-field radiography is a novel X-ray imaging modality that enables complementary diagnostic information by visualizing the microstructural properties of lung tissue. Implemented via a Talbot-Lau interferometer integrated into a…

Analyzing large X-ray diffraction (XRD) datasets is a key step in high-throughput mapping of the compositional phase diagrams of combinatorial materials libraries. Optimizing and automating this task can help accelerate the process of…

Automated segmentation of multiple sclerosis (MS) lesions using multicontrast magnetic resonance (MR) images improves efficiency and reproducibility compared to manual delineation, with deep learning (DL) methods achieving state-of-the-art…

Optical aberrations prevent telescopes from reaching their theoretical diffraction limit. Once estimated, these aberrations can be compensated for using deformable mirrors in a closed loop. Focal plane wavefront sensing enables the…

The computer-aided diagnosis of focal liver lesions (FLLs) can help improve workflow and enable correct diagnoses; FLL detection is the first step in such a computer-aided diagnosis. Despite the recent success of deep-learning-based…

Image and Video Processing · Electrical Eng. & Systems 2021-12-20 Sang-gil Lee , Eunji Kim , Jae Seok Bae , Jung Hoon Kim , Sungroh Yoon

Common-path digital in-line holography is considered as a valuable 3D diagnostic techniques for a wide range of applications. This configuration is cost effective and relatively immune to variation in the experimental environment.…

Instrumentation and Detectors · Physics 2016-01-20 Nicolas Verrier , Corinne Fournier , Anthony Cazier , Thierry Fournel

Photomixing of two near-infrared lasers is well established for continuous-wave terahertz spectroscopy. Photomixing of three lasers allows us to measure at three terahertz frequencies simultaneously. Similar to Fourier spectroscopy, the…

X-ray phase-contrast imaging offers enhanced sensitivity for weakly-attenuating materials, such as breast and brain tissue, but has yet to be widely implemented clinically due to high coherence requirements and expensive x-ray optics.…

Medical Physics · Physics 2023-05-04 Serena Qinyun Z. Shi , Nadav Shapira , Peter B. Noël , Sebastian Meyer

We propose a technique, to be used for time-resolved pump-probe experiments, for timing an x-ray free electron laser (XFEL) to a high-power conventional laser with femtosecond accuracy. Our method takes advantage of the same electron bunch…

Accelerator Physics · Physics 2009-11-13 Gianluca Geloni , Evgeni Saldin , Evgeni Schneidmiller , Mikhail Yurkov

X-ray absorption spectroscopy (XAS) is a powerful technique to probe the electronic and structural properties of materials. With the rapid growth in both the volume and complexity of XAS datasets driven by advancements in synchrotron…

Computational Physics · Physics 2025-02-25 Xue Han , Haodong Yao , Fei Zhan , Xueqi Song , Junfang Zhao , Haifeng Zhao

Correlative microscopy is a powerful technique that combines the advantages of multiple imaging modalities to achieve a comprehensive understanding of investigated samples. For example, fluorescence microscopy provides unique functional…

We propose a novel data-driven approach for analyzing synchrotron Laue X-ray microdiffraction scans based on machine learning algorithms. The basic architecture and major components of the method are formulated mathematically. We…

Materials Science · Physics 2020-10-12 Yintao Song , Nobumichi Tamura , Chenbo Zhang , Mostafa Karami , Xian Chen

Time-resolved x-ray magnetic circular dichroism (XMCD) enables a unique spectroscopic view on complex spin and charge dynamics in multi-elemental magnetic materials. So far, its application in the soft-x-ray range has been limited to…

High-power multi-beam klystrons represent a key component to amplify RF to generate the accelerating field of the superconducting radio frequency (SRF) cavities at European XFEL. Exchanging these high-power components takes time and effort,…

Accelerator Physics · Physics 2024-05-22 Antonin Sulc , Annika Eichler , Tim Wilksen