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X-ray Free Electron Lasers (XFEL) are revolutionary photons sources, whose ultrashort, brilliant pulses are expected to allow single molecule diffraction experiments providing structural information on the atomic length scale. This ultimate…

Optics · Physics 2015-05-20 Andrea Fratalocchi , Giancarlo Ruocco

The European X-ray Free Electron Laser (XFEL.EU) will provide as-yet-unrivaled peak brilliance and ultra-short pulses of spatially coherent X-rays with a pulse length of less than 100 fs in the energy range between 0.25 and 25 keV. The high…

Instrumentation and Detectors · Physics 2015-06-15 Jolanta Sztuk-Dambietz , Steffen Hauf , Andreas Koch , Markus Kuster , Monica Turcato

Macro X-ray Fluorescence (MA-XRF) scanning is increasingly widely used by researchers in heritage science to analyse easel paintings as one of a suite of non-invasive imaging techniques. The task of processing the resulting MA-XRF datacube…

Signal Processing · Electrical Eng. & Systems 2024-06-27 Su Yan , Jun-Jie Huang , Herman Verinaz-Jadan , Nathan Daly , Catherine Higgitt , Pier Luigi Dragotti

X-ray free-electron lasers (XFELs) of high brightness have opened new opportunities for exploring ultrafast dynamical processes in matter, enabling imaging and movies of single molecules and particles at atomic resolution. In this paper, we…

X-ray free electron laser (XFEL) can provide X-ray light with about four order of magnitude higher flux than synchrotron radiation. Pulse light from XFEL interacts with the target and the resulting photons are collected by detectors. The…

Instrumentation and Detectors · Physics 2021-10-13 Shuo Zhang , Jing-Kai Xia , Xu-Dong Ju

Serial electron diffraction (SerialED) is an emerging technique, which applies the snapshot data-collection mode of serial X-ray crystallography to three-dimensional electron diffraction (3D ED), forgoing the conventional rotation method.…

Data Analysis, Statistics and Probability · Physics 2020-11-06 Robert Bücker , Pascal Hogan-Lamarre , R. J. Dwayne Miller

In order to measure the radial displacements of facets on surface of a growing spherical Cu_{2-\delta}Se crystal with sub-nanometer resolution, we have investigated the reliability and accuracy of standard method of Fourier analysis of…

Optics · Physics 2009-11-13 Jadranko Gladic , Zlatko Vucic , Davorin Lovric

Modeling of large-scale research facilities is extremely challenging due to complex physical processes and engineering problems. Here, we adopt a data-driven approach to model the longitudinal phase-space diagnostic beamline at the…

Machine Learning · Computer Science 2021-08-11 Jun Zhu , Ye Chen , Frank Brinker , Winfried Decking , Sergey Tomin , Holger Schlarb

Single-particle imaging experiments of biomolecules at x-ray free-electron lasers (XFELs) require processing of hundreds of thousands (or more) of images that contain very few x-rays. Each low-flux image of the diffraction pattern is…

Instrumentation and Detectors · Physics 2012-03-16 Hugh T. Philipp , Kartik Ayyer , Mark W. Tate , Veit Elser , Sol M. Gruner

Existing FEL facilities often suffer from stability issues: so electron orbit, transverse electron optics, electron bunch compression and other parameters have to be readjusted often to account for drifts in performance of various…

Accelerator Physics · Physics 2017-04-11 I. Agapov , G. Geloni , S. Tomin , I. Zagorodnov

Real-time 3D fluorescence microscopy is crucial for the spatiotemporal analysis of live organisms, such as neural activity monitoring. The eXtended field-of-view light field microscope (XLFM), also known as Fourier light field microscope,…

Image and Video Processing · Electrical Eng. & Systems 2023-06-16 Josué Page Vizcaíno , Panagiotis Symvoulidis , Zeguan Wang , Jonas Jelten , Paolo Favaro , Edward S. Boyden , Tobias Lasser

Dark-field X-ray microscopy (DFXM) is a nondestructive full-field imaging technique providing three dimensional mapping of microstructure and local strain fields in deeply embedded crystalline elements. This is achieved by placing an…

X-ray speckles have been used for a wide variety of experiments, ranging from imaging (and tomography), wavefront sensing, spatial coherence measurements all the way to x-ray photon correlation spectroscopy (XPCS) and ptychography. In the…

Medical Physics · Physics 2024-04-19 Rafael Celestre , Laurene Quenot , Christopher Ninham , Emmanuel Brun , Luca Fardin

Many modern large-scale facilities, like European X-ray Free Electron Laser (E-XFEL), require precise synchronisation, often down to femtosecond level. Even a very short interruption or an excessive glitch in the reference signal might…

Instrumentation and Detectors · Physics 2018-06-26 Bartosz Gąsowski , Tomasz Owczarek , Krzysztof Czuba , Łukasz Zembala , Holger Schlarb

The nonlinear interaction of x-rays with matter is at the heart of understanding and controlling ultrafast molecular dynamics from an atom-specific viewpoint, providing new scientific and analytical opportunities to explore the structure…