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Acute lymphoblastic leukemia (ALL) is the most malignant form of leukemia and the most common cancer in adults and children. Traditionally, leukemia is diagnosed by analyzing blood and bone marrow smears under a microscope, with additional…

Image and Video Processing · Electrical Eng. & Systems 2024-10-21 Maksuda Akter , Rabea Khatun , Md Manowarul Islam

Deep learning models for survival analysis have gained significant attention in the literature, but they suffer from severe performance deficits when the dataset contains many irrelevant features. We give empirical evidence for this problem…

Machine Learning · Computer Science 2019-03-08 Carl Rietschel , Jinsung Yoon , Mihaela van der Schaar

Feature importance aims at measuring how crucial each input feature is for model prediction. It is widely used in feature engineering, model selection and explainable artificial intelligence (XAI). In this paper, we propose a new tree-model…

Machine Learning · Statistics 2020-09-17 Fan Fang , Carmine Ventre , Lingbo Li , Leslie Kanthan , Fan Wu , Michail Basios

Explainable AI (XAI) is a research area whose objective is to increase trustworthiness and to enlighten the hidden mechanism of opaque machine learning techniques. This becomes increasingly important in case such models are applied to the…

Machine Learning · Computer Science 2021-04-19 Danilo Numeroso , Davide Bacciu

Explainable artificial intelligence (XAI) plays an indispensable role in demystifying the decision-making processes of AI, especially within the healthcare industry. Clinicians rely heavily on detailed reasoning when making a diagnosis,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Anna Stubbin , Thompson Chyrikov , Jim Zhao , Christina Chajo

The choice of parameters, and the design of the network architecture are important factors affecting the performance of deep neural networks. Genetic Algorithms (GA) have been used before to determine parameters of a network. Yet, GAs…

Computer Vision and Pattern Recognition · Computer Science 2018-09-28 Yantao Lu , Burak Kakillioglu , Senem Velipasalar

Due to the rapid innovation of technology and the desire to find and employ biomarkers for neurodegenerative disease, high-dimensional data classification problems are routinely encountered in neuroimaging studies. To avoid over-fitting and…

Machine Learning · Statistics 2018-06-19 Shan Shi , Farouk Nathoo

Genetic programming (GP) has the potential to generate explainable results, especially when used for dimensionality reduction. In this research, we investigate the potential of leveraging eXplainable AI (XAI) and large language models…

Neural and Evolutionary Computing · Computer Science 2024-03-07 Paula Maddigan , Andrew Lensen , Bing Xue

Explainable artificial intelligence (XAI) is an important and rapidly expanding research topic. The goal of XAI is to gain trust in a machine learning (ML) model through clear insights into how the model arrives at its predictions. Genetic…

Neural and Evolutionary Computing · Computer Science 2022-03-28 E. M. C. Sijben , T. Alderliesten , P. A. N. Bosman

Hyperparameter optimization is a challenging problem in developing deep neural networks. Decision of transfer layers and trainable layers is a major task for design of the transfer convolutional neural networks (CNN). Conventional transfer…

Neural and Evolutionary Computing · Computer Science 2021-03-08 Chen Li , JinZhe Jiang , YaQian Zhao , RenGang Li , EnDong Wang , Xin Zhang , Kun Zhao

Cancer is a term that denotes a group of diseases caused by abnormal growth of cells that can spread in different parts of the body. According to the World Health Organization (WHO), cancer is the second major cause of death after…

Machine Learning · Computer Science 2023-01-31 Fadi Alharbi , Aleksandar Vakanski

Many problems within personalized medicine and digital health rely on the analysis of continuous-time functional biomarkers and other complex data structures emerging from high-resolution patient monitoring. In this context, this work…

Machine Learning · Statistics 2025-01-14 Marcos Matabuena

In biological research machine learning algorithms are part of nearly every analytical process. They are used to identify new insights into biological phenomena, interpret data, provide molecular diagnosis for diseases and develop…

The past years have seen a considerable increase in cancer cases. However, a cancer diagnosis is often complex and depends on the types of images provided for analysis. It requires highly skilled practitioners but is often time-consuming…

Image and Video Processing · Electrical Eng. & Systems 2022-10-24 Solene Bechelli

Advancements in high-throughput technologies have led to a shift from traditional hypothesis-driven methodologies to data-driven approaches. Multi-omics refers to the integrative analysis of data derived from multiple 'omes', such as…

Genomics · Quantitative Biology 2024-10-17 Ahmad Hussein , Mukesh Prasad , Ali Braytee

The integration of artificial intelligence (AI) into medicine is remarkable, offering advanced diagnostic and therapeutic possibilities. However, the inherent opacity of complex AI models presents significant challenges to their clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Binbin Wen , Yihang Wu , Tareef Daqqaq , Ahmad Chaddad

In this paper we introduce Feature Gradients, a gradient-based search algorithm for feature selection. Our approach extends a recent result on the estimation of learnability in the sublinear data regime by showing that the calculation can…

Machine Learning · Statistics 2019-08-29 Rishit Sheth , Nicolo Fusi

This paper provides a critical review of the literature on deep learning applications in breast tumor diagnosis using ultrasound and mammography images. It also summarizes recent advances in computer-aided diagnosis (CAD) systems, which…

Image and Video Processing · Electrical Eng. & Systems 2020-10-05 Yuliana Jiménez-Gaona , María José Rodríguez-Álvarez , Vasudevan Lakshminarayanan

Gene expression classification is a pivotal yet challenging task in bioinformatics, primarily due to the high dimensionality of genomic data and the risk of overfitting. To bridge this gap, we propose BOLIMES, a novel feature selection…

Machine Learning · Computer Science 2025-02-27 Bich-Chung Phan , Thanh Ma , Huu-Hoa Nguyen , Thanh-Nghi Do

In this work we set out to find a method to classify protein structures using a Deep Learning methodology. Our Artificial Intelligence has been trained to recognize complex biomolecule structures extrapolated from the Protein Data Bank…

Machine Learning · Computer Science 2021-11-04 Damiano Perri , Marco Simonetti , Andrea Lombardi , Noelia Faginas-Lago , Osvaldo Gervasi