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Related papers: End-to-End $n$-ary Relation Extraction for Combina…

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Combination therapies have become the standard of care for diseases such as cancer, tuberculosis, malaria and HIV. However, the combinatorial set of available multi-drug treatments creates a challenge in identifying effective combination…

Computation and Language · Computer Science 2022-05-06 Aryeh Tiktinsky , Vijay Viswanathan , Danna Niezni , Dana Meron Azagury , Yosi Shamay , Hillel Taub-Tabib , Tom Hope , Yoav Goldberg

Automated Drug Combination Extraction (DCE) from large-scale biomedical literature is crucial for advancing precision medicine and pharmacological research. However, existing relation extraction methods primarily focus on binary…

Computation and Language · Computer Science 2026-03-10 Zhijun Wang , Ling Luo , Dinghao Pan , Huan Zhuang , Lejing Yu , Yuanyuan Sun , Hongfei Lin

Most information extraction methods focus on binary relations expressed within single sentences. In high-value domains, however, $n$-ary relations are of great demand (e.g., drug-gene-mutation interactions in precision oncology). Such…

Computation and Language · Computer Science 2019-06-28 Robin Jia , Cliff Wong , Hoifung Poon

Adverse drug events (ADEs) are unexpected incidents caused by the administration of a drug or medication. To identify and extract these events, we require information about not just the drug itself but attributes describing the drug (e.g.,…

Computation and Language · Computer Science 2021-04-23 Darshini Mahendran , Bridget T. McInnes

The best evidence concerning comparative treatment effectiveness comes from clinical trials, the results of which are reported in unstructured articles. Medical experts must manually extract information from articles to inform…

Computation and Language · Computer Science 2022-01-11 Benjamin E. Nye , Jay DeYoung , Eric Lehman , Ani Nenkova , Iain J. Marshall , Byron C. Wallace

miRNA mRNA relations are closely linked to several biological processes and disease mechanisms In a recent study we tested the performance of large language models LLMs on extracting miRNA mRNA relations from PubMed PubMedBERT achieved the…

Joint entity-relation extraction is a critical task in transforming unstructured or semi-structured text into triplets, facilitating the construction of large-scale knowledge graphs, and supporting various downstream applications. Despite…

Computation and Language · Computer Science 2025-02-14 Danni Feng , Runzhi Li , Jing Wang , Siyu Yan , Lihong Ma , Yunli Xing

Relation extraction between drugs plays a crucial role in identifying drug drug interactions and predicting side effects. The advancement of machine learning methods in relation extraction, along with the development of large medical text…

Computation and Language · Computer Science 2025-10-28 Ali Fata , Hossein Rahmani , Parinaz Soltanzadeh , Amirhossein Derakhshan , Behrouz Minaei Bidgoli

Medication Extraction and Mining play an important role in healthcare NLP research due to its practical applications in hospital settings, such as their mapping into standard clinical knowledge bases (SNOMED-CT, BNF, etc.). In this work, we…

Computation and Language · Computer Science 2024-12-31 Pablo Romero , Lifeng Han , Goran Nenadic

Relation extraction is a fundamental problem in natural language processing. Most existing models are defined for relation extraction in the general domain. However, their performance on specific domains (e.g., biomedicine) is yet unclear.…

Computation and Language · Computer Science 2021-12-14 Yongkang Li

Adverse reaction caused by drugs is a potentially dangerous problem which may lead to mortality and morbidity in patients. Adverse Drug Event (ADE) extraction is a significant problem in biomedical research. We model ADE extraction as a…

Computation and Language · Computer Science 2018-01-03 Suriyadeepan Ramamoorthy , Selvakumar Murugan

Adverse drug reactions (ADRs) are unwanted or harmful effects experienced after the administration of a certain drug or a combination of drugs, presenting a challenge for drug development and drug administration. In this paper, we present a…

Computation and Language · Computer Science 2019-05-29 Maksim Belousov , Nikola Milosevic , William Dixon , Goran Nenadic

Side effects of prescribed medications are a common occurrence. Electronic healthcare databases present the opportunity to identify new side effects efficiently but currently the methods are limited due to confounding (i.e. when an…

Databases · Computer Science 2016-11-17 Jenna M. Reps , Uwe Aickelin , Jiangang Ma , Yanchun Zhang

In recent years extracting relevant information from biomedical and clinical texts such as research articles, discharge summaries, or electronic health records have been a subject of many research efforts and shared challenges. Relation…

Computation and Language · Computer Science 2016-07-01 Sunil Kumar Sahu , Ashish Anand , Krishnadev Oruganty , Mahanandeeshwar Gattu

When patients need to take medicine, particularly taking more than one kind of drug simultaneously, they should be alarmed that there possibly exists drug-drug interaction. Interaction between drugs may have a negative impact on patients or…

Computation and Language · Computer Science 2020-08-31 Siliang Tang , Qi Zhang , Tianpeng Zheng , Mengdi Zhou , Zhan Chen , Lixing Shen , Xiang Ren , Yueting Zhuang , Shiliang Pu , Fei Wu

Drug-drug interaction (DDI) is a vital information when physicians and pharmacists intend to co-administer two or more drugs. Thus, several DDI databases are constructed to avoid mistakenly combined use. In recent years, automatically…

Computation and Language · Computer Science 2017-05-19 Zibo Yi , Shasha Li , Jie Yu , Qingbo Wu

Extracting fine-grained experimental findings from literature can provide dramatic utility for scientific applications. Prior work has developed annotation schemas and datasets for limited aspects of this problem, failing to capture the…

Computation and Language · Computer Science 2024-04-26 Aakanksha Naik , Bailey Kuehl , Erin Bransom , Doug Downey , Tom Hope

Drug combination therapy is a well-established strategy for disease treatment with better effectiveness and less safety degradation. However, identifying novel drug combinations through wet-lab experiments is resource intensive due to the…

Machine Learning · Computer Science 2023-01-18 Zhihang Hu , Qinze Yu , Yucheng Guo , Taifeng Wang , Irwin King , Xin Gao , Le Song , Yu Li

The development of deep neural networks has improved representation learning in various domains, including textual, graph structural, and relational triple representations. This development opened the door to new relation extraction beyond…

Computation and Language · Computer Science 2022-12-22 Masaki Asada

Medical knowledge extraction methods based on edge computing deploy deep learning models on edge devices to achieve localized entity and relation extraction. This approach avoids transferring substantial sensitive data to cloud data…

Computation and Language · Computer Science 2024-01-17 Fan Lu , Quan Qi , Huaibin Qin
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