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The recent advancement of spatial transcriptomics (ST) allows to characterize spatial gene expression within tissue for discovery research. However, current ST platforms suffer from low resolution, hindering in-depth understanding of…

Image and Video Processing · Electrical Eng. & Systems 2025-11-05 Xiaofei Wang , Xingxu Huang , Stephen J. Price , Chao Li

In this big data era, the use of large dataset in conjunction with machine learning (ML) has been increasingly popular in both industry and academia. In recent times, the field of materials science is also undergoing a big data revolution,…

Materials Science · Physics 2023-09-27 Sue Sin Chong , Yi Sheng Ng , Hui-Qiong Wang , Jin-Cheng Zheng

Cancer research is increasingly driven by the integration of diverse data modalities, spanning from genomics and proteomics to imaging and clinical factors. However, extracting actionable insights from these vast and heterogeneous datasets…

Over the last several years, the use of machine learning (ML) in neuroscience has been rapidly increasing. Here, we review ML's contributions, both realized and potential, across several areas of systems neuroscience. We describe four…

Neurons and Cognition · Quantitative Biology 2018-11-27 Joshua I. Glaser , Ari S. Benjamin , Roozbeh Farhoodi , Konrad P. Kording

Machine learning (ML) methods can expand our ability to construct, and draw insight from large datasets. Despite the increasing volume of planetary observations, our field has seen few applications of ML in comparison to other sciences. To…

Aim: To review how machine learning (ML) is applied to imaging biomarkers in neuro-oncology, in particular for diagnosis, prognosis, and treatment response monitoring. Materials and Methods: The PubMed and MEDLINE databases were searched…

Quantitative Methods · Quantitative Biology 2019-10-17 Thomas Booth , Matthew Williams , Aysha Luis , Jorge Cardoso , Ashkan Keyoumars , Haris Shuaib

Nuclear materials are often demanded to function for extended time in extreme environments, including high radiation fluxes and transmutation, high temperature and temperature gradients, stresses, and corrosive coolants. They also have a…

Materials Science · Physics 2022-11-18 Dane Morgan , Ghanshyam Pilania , Adrien Couet , Blas P. Uberuaga , Cheng Sun , Ju Li

In the emerging era of big data, larger available clinical datasets and computational advances have sparked a massive interest in machine learning-based approaches. The number of manuscripts related to machine learning or artificial…

Machine Learning · Statistics 2020-06-29 Julius M. Kernbach , Victor E. Staartjes

In a world where new domains are constantly discovered and machine learning (ML) is applied to automate new tasks every day, challenges arise with the number of samples available to train ML models. While the traditional ML training relies…

Machine Learning · Computer Science 2025-04-08 Andrea Gajic , Sudip Vhaduri

High-throughput technologies such as next generation sequencing allow biologists to observe cell function with unprecedented resolution, but the resulting datasets are too large and complicated for humans to understand without the aid of…

Applications · Statistics 2021-10-08 David S. Watson

Globally, there is a substantial unmet need to diagnose various diseases effectively. The complexity of the different disease mechanisms and underlying symptoms of the patient population presents massive challenges to developing the early…

Machine Learning · Computer Science 2022-01-03 Md Manjurul Ahsan , Zahed Siddique

The increasing global prevalence of mental disorders, such as depression and PTSD, requires objective and scalable diagnostic tools. Traditional clinical assessments often face limitations in accessibility, objectivity, and consistency.…

Audio and Speech Processing · Electrical Eng. & Systems 2025-04-03 Abdelrahaman A. Hassan , Abdelrahman A. Ali , Aya E. Fouda , Radwa J. Hanafy , Mohammed E. Fouda

When nanoparticles (NPs) are introduced into a biological solution, layers of biomolecules form on their surface, creating a corona. Understanding how the structure of the protein evolves into the corona is essential for evaluating the…

Multi-modal large language models (MLLMs) have rapidly advanced in visual tasks, yet their spatial understanding remains limited to single images, leaving them ill-suited for physical-world applications that require multi-frame reasoning.…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Runsen Xu , Weiyao Wang , Hao Tang , Xingyu Chen , Xiaodong Wang , Fu-Jen Chu , Matt Feiszli , Kevin J. Liang

Detection of easily missed hidden patterns with fast processing power makes machine learning (ML) indispensable to today's healthcare system. Though many ML applications have already been discovered and many are still under investigation,…

Machine Learning · Computer Science 2023-07-27 Mrinmoy Roy , Sarwar J. Minar , Porarthi Dhar , A T M Omor Faruq

Recent technological advancements in data acquisition tools allowed life scientists to acquire multimodal data from different biological application domains. Broadly categorized in three types (i.e., sequences, images, and signals), these…

Quantitative Methods · Quantitative Biology 2020-03-03 Mufti Mahmud , M Shamim Kaiser , Amir Hussain

This review maps developments in stochastic modeling, highlighting non-standard approaches and their applications to biology and epidemiology. It brings together four strands: (1) core models for systems that evolve with randomness; (2)…

Dynamical Systems · Mathematics 2025-10-24 Yassine Sabbar , Kottakkaran Sooppy Nisar

Self-supervised learning (SSL) has emerged as a promising paradigm in medical imaging, addressing the chronic challenge of limited labeled data in healthcare settings. While SSL has shown impressive results, existing studies in the medical…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Valay Bundele , Karahan Sarıtaş , Bora Kargi , Oğuz Ata Çal , Kıvanç Tezören , Zohreh Ghaderi , Hendrik Lensch

Large Language Models (LLMs) are revolutionizing bioinformatics, enabling advanced analysis of DNA, RNA, proteins, and single-cell data. This survey provides a systematic review of recent advancements, focusing on genomic sequence modeling,…

Computation and Language · Computer Science 2026-03-03 Zhenyu Wang , Zikang Wang , Jiyue Jiang , Pengan Chen , Xiangyu Shi , Yu Li

Atomic force microscopy (AFM or SPM) imaging is one of the best matches with machine learning (ML) analysis among microscopy techniques. The digital format of AFM images allows for direct utilization in ML algorithms without the need for…

Biological Physics · Physics 2025-01-07 Igor Sokolov