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Classical regression methods treat covariates as a vector and estimate a corresponding vector of regression coefficients. Modern applications in medical imaging generate covariates of more complex form such as multidimensional arrays…

Methodology · Statistics 2013-10-22 Hua Zhou , Lexin Li , Hongtu Zhu

Most brain disorders are very heterogeneous in terms of their underlying biology and developing analysis methods to model such heterogeneity is a major challenge. A promising approach is to use probabilistic regression methods to estimate…

Machine Learning · Statistics 2018-12-03 Seyed Mostafa Kia , Christian F. Beckmann , Andre F. Marquand

Tensor-based representations are being increasingly used to represent complex data types such as imaging data, due to their appealing properties such as dimension reduction and the preservation of spatial information. Recently, there is a…

Methodology · Statistics 2023-12-15 Rongke Lyu , Marina Vannucci , Suprateek Kundu

Large-scale neuroimaging studies have been collecting brain images of study individuals, which take the form of two-dimensional, three-dimensional, or higher dimensional arrays, also known as tensors. Addressing scientific questions arising…

Methodology · Statistics 2013-04-23 Xiaoshan Li , Hua Zhou , Lexin Li

This article proposes a Bayesian approach to regression with a scalar response against vector and tensor covariates. Tensor covariates are commonly vectorized prior to analysis, failing to exploit the structure of the tensor, and resulting…

Methodology · Statistics 2015-09-23 Rajarshi Guhaniyogi , Shaan Qamar , David B. Dunson

Aiming at abundant scientific and engineering data with not only high dimensionality but also complex structure, we study the regression problem with a multidimensional array (tensor) response and a vector predictor. Applications include,…

Methodology · Statistics 2015-02-02 Lexin Li , Xin Zhang

The assessment of Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI) associated with brain changes remains a challenging task. Recent studies have demonstrated that combination of multi-modality imaging techniques can better…

Machine Learning · Computer Science 2022-09-26 Jun Yu , Zhaoming Kong , Liang Zhan , Li Shen , Lifang He

Higher-order tensors have received increased attention across science and engineering. While most tensor decomposition methods are developed for a single tensor observation, scientific studies often collect side information, in the form of…

Methodology · Statistics 2021-10-29 Jiaxin Hu , Chanwoo Lee , Miaoyan Wang

With rapid advances in neuroimaging techniques, the research on brain disorder identification has become an emerging area in the data mining community. Brain disorder data poses many unique challenges for data mining research. For example,…

Machine Learning · Computer Science 2015-08-06 Bokai Cao , Xiangnan Kong , Philip S. Yu

Current high-throughput data acquisition technologies probe dynamical systems with different imaging modalities, generating massive data sets at different spatial and temporal resolutions posing challenging problems in multimodal data…

Fitting regression models with many multivariate responses and covariates can be challenging, but such responses and covariates sometimes have tensor-variate structure. We extend the classical multivariate regression model to exploit such…

Methodology · Statistics 2023-01-31 Carlos Llosa-Vite , Ranjan Maitra

A major interest in longitudinal neuroimaging studies involves investigating voxel-level neuroplasticity due to treatment and other factors across visits. However, traditional voxel-wise methods are beset with several pitfalls, which can…

Neurons and Cognition · Quantitative Biology 2023-10-19 Suprateek Kundu , Alec Reinhardt , Serena Song , Joo Han , M. Lawson Meadows , Bruce Crosson , Venkatagiri Krishnamurthy

Time-varying parameter vector autoregression provides a flexible framework to capture structural changes within time series. However, when applied to high-dimensional data, this model encounters challenges of over-parametrization and…

Methodology · Statistics 2025-05-14 Yiyong Luo , Jim E. Griffin

Diffusion tensor imaging provides important information on tissue structure and orientation of fiber tracts in brain white matter in vivo. It results in diffusion tensors, which are $3\times3$ symmetric positive definite (SPD) matrices,…

Applications · Statistics 2013-04-17 Ying Yuan , Hongtu Zhu , Martin Styner , John H. Gilmore , J. S. Marron

Tensor regression has attracted significant attention in statistical research. This study tackles the challenge of handling covariates with smooth varying structures. We introduce a novel framework, termed functional tensor regression,…

Methodology · Statistics 2025-06-12 Tongyu Li , Fang Yao , Anru R. Zhang

We propose a novel tensor-on-tensor modeling framework that flexibly models nonlinear voxel-level relationships using Gaussian process (GP) priors, while incorporating the spatial structure of the output tensor through low-rank tensor-based…

Methodology · Statistics 2026-04-10 Yajie Liu , Hengrui Luo , Suprateek Kundu

In modern data science, dynamic tensor data is prevailing in numerous applications. An important task is to characterize the relationship between such dynamic tensor and external covariates. However, the tensor data is often only partially…

Machine Learning · Statistics 2021-05-17 Jie Zhou , Will Wei Sun , Jingfei Zhang , Lexin Li

Point process modeling is gaining increasing attention, as point process type data are emerging in numerous scientific applications. In this article, motivated by a neuronal spike trains study, we propose a novel point process regression…

Methodology · Statistics 2020-12-10 Xiwei Tang , Lexin Li

In contemporary neuroscience, a key area of interest is dynamic effective connectivity, which is crucial for understanding the dynamic interactions and causal relationships between different brain regions. Dynamic effective connectivity can…

Methodology · Statistics 2024-05-30 Wei Zhang , Ivor Cribben , sonia Petrone , Michele Guindani

As a general and robust alternative to traditional mean regression models, quantile regression avoids the assumption of normally distributed errors, making it a versatile choice when modeling outcomes such as cognitive scores that typically…

Methodology · Statistics 2026-03-19 Rongke Lyu , Marina Vannucci , Suprateek Kundu
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