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Related papers: CryoFormer: Continuous Heterogeneous Cryo-EM Recon…

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Recent advances in 3D facial expression reconstruction have demonstrated remarkable performance in capturing macro-expressions, yet the reconstruction of micro-expressions remains unexplored. This novel task is particularly challenging due…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Che Sun , Xinjie Zhang , Rui Gao , Xu Chen , Yuwei Wu , Yunde Jia

Cryo-EM data processing typically focuses on the structure of the main conformational state under investigation and discards images that belong to other states. This approach can reach atomic resolution, but ignores vast amounts of valuable…

Biomolecules · Quantitative Biology 2024-02-20 Felix Lambrecht , Andreas Kröpelin , Mario Lüttich , Michael Habeck , David Haselbach , Holger Stark

Background and Objective: The contrast of cryo-EM images varies from one to another, primarily due to the uneven thickness of the ice layer. This contrast variation can affect the quality of 2-D class averaging, 3-D ab-initio modeling, and…

Computer Vision and Pattern Recognition · Computer Science 2022-07-01 Yunpeng Shi , Amit Singer

The temporal complexity of electronic health record (EHR) data presents significant challenges for predicting clinical outcomes using machine learning. This paper proposes ChronoFormer, an innovative transformer based architecture…

Machine Learning · Computer Science 2025-04-11 Yuanyun Zhang , Shi Li

Cryo-electron microscopy can now routinely deliver atomic resolution structures for a variety of biological systems. The relevance and value of these structures is directly related to their ability to help rationalize experimental…

Electroencephalography (EEG)-based visual perception reconstruction has become an important area of research. Neuroscientific studies indicate that humans can decode imagined 3D objects by perceiving or imagining various visual information,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Xin Xiang , Wenhui Zhou , Guojun Dai

This paper presents a fractional one-dimensional convolutional neural network (CNN) autoencoder for denoising the Electroencephalogram (EEG) signals which often get contaminated with noise during the recording process, mostly due to muscle…

Machine Learning · Computer Science 2021-04-19 Subham Nagar , Ahlad Kumar

The living body is composed of innumerable fine and complex structures and although these structures have been studied in the past, a vast amount of information pertaining to them still remains unknown. When attempting to observe these…

Medical Physics · Physics 2021-11-30 Raku Son , Kenji Yamazawa , Akiko Oguchi , Mitsuo Suga , Masaru Tamura , Yasuhiro Murakawa , Satoshi Kume

Cellular Electron Cryotomography (CryoET) offers the ability to look inside cells and observe macromolecules frozen in action. A primary challenge for this technique is identifying and extracting the molecular components within the crowded…

Quantitative Methods · Quantitative Biology 2021-08-04 Muyuan Chen , Wei Dai , Ying Sun , Darius Jonasch , Cynthia Y He , Michael F. Schmid , Wah Chiu , Steven J Ludtke

Most modern deep learning-based multi-view 3D reconstruction techniques use RNNs or fusion modules to combine information from multiple images after independently encoding them. These two separate steps have loose connections and do not…

Computer Vision and Pattern Recognition · Computer Science 2022-07-11 Farid Yagubbayli , Yida Wang , Alessio Tonioni , Federico Tombari

Reconstructing the three-dimensional (3D) geometry of object surfaces is essential for robot perception, yet vision-based approaches are generally unreliable under low illumination or occlusion. This limitation motivates the design of a…

Robotics · Computer Science 2026-01-21 Guanyu Xu , Jiaqi Wang , Dezhong Tong , Xiaonan Huang

Cryogenic Electron Tomography (CryoET) is a useful imaging technology in structural biology that is hindered by its need for manual annotations, especially in particle picking. Recent works have endeavored to remedy this issue with few-shot…

Quantitative Methods · Quantitative Biology 2024-07-10 Yizhou Zhao , Hengwei Bian , Michael Mu , Mostofa R. Uddin , Zhenyang Li , Xiang Li , Tianyang Wang , Min Xu

The past decade's "cryoEM revolution" has produced exponential growth in high-resolution structural data through advances in cryogenic electron microscopy (cryoEM) and tomography (cryoET). Deep learning integration into structural…

Quantitative Methods · Quantitative Biology 2025-07-29 Brady K. Zhou , Jason J. Hu , Jane K. J. Lee , Z. Hong Zhou , Demetri Terzopoulos

We introduce a novel, data-driven approach for reconstructing temporally coherent 3D motion from unstructured and potentially partial observations of non-rigidly deforming shapes. Our goal is to achieve high-fidelity motion reconstructions…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Aymen Merrouche , Stefanie Wuhrer , Edmond Boyer

Knowledge of a protein's atomic conformational ensemble is critical to determining its function, yet state-of-the-art ensemble prediction models are limited by lack of high-quality conformational data from simulation or experiment. Recent…

Machine Learning · Computer Science 2026-05-12 Jay Shenoy , Miro Astore , Axel Levy , Frédéric Poitevin , Sonya M. Hanson , Gordon Wetzstein

In this work we propose a novel model-based deep convolutional autoencoder that addresses the highly challenging problem of reconstructing a 3D human face from a single in-the-wild color image. To this end, we combine a convolutional…

Computer Vision and Pattern Recognition · Computer Science 2017-12-11 Ayush Tewari , Michael Zollhöfer , Hyeongwoo Kim , Pablo Garrido , Florian Bernard , Patrick Pérez , Christian Theobalt

Cellular Electron Cryo-Tomography (CECT) is a powerful 3D imaging tool for studying the native structure and organization of macromolecules inside single cells. For systematic recognition and recovery of macromolecular structures captured…

Computer Vision and Pattern Recognition · Computer Science 2018-07-04 Chang Liu , Xiangrui Zeng , Kaiwen Wang , Qiang Guo , Min Xu

Transformers have demonstrated remarkable performance in natural language processing and computer vision. However, existing vision Transformers struggle to learn from limited medical data and are unable to generalize on diverse medical…

Image and Video Processing · Electrical Eng. & Systems 2023-04-06 Yunhe Gao , Mu Zhou , Di Liu , Zhennan Yan , Shaoting Zhang , Dimitris N. Metaxas

Phase reconstruction is important in transmission electron microscopy for structural studies. We describe electron Fourier ptychography and its application to phase reconstruction of both radiation-resistant and beam-sensitive materials. We…

The problem of image restoration in cryo-EM entails correcting for the effects of the Contrast Transfer Function (CTF) and noise. Popular methods for image restoration include `phase flipping', which corrects only for the Fourier phases but…

Computer Vision and Pattern Recognition · Computer Science 2016-04-29 Tejal Bhamre , Teng Zhang , Amit Singer