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Cell and nucleus segmentation are fundamental tasks for quantitative bioimage analysis. Despite progress in recent years, biologists and other domain experts still require novel algorithms to handle increasingly large and complex real-world…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Thibaut Goldsborough , Ben Philps , Alan O'Callaghan , Fiona Inglis , Leo Leplat , Andrew Filby , Hakan Bilen , Peter Bankhead

Accurate segmentation and classification of brain tumors from Magnetic Resonance Imaging (MRI) remain key challenges in medical image analysis, primarily due to the lack of high-quality, balanced, and diverse datasets with expert…

Image and Video Processing · Electrical Eng. & Systems 2026-01-29 Amirreza Fateh , Yasin Rezvani , Sara Moayedi , Sadjad Rezvani , Fatemeh Fateh , Mansoor Fateh , Vahid Abolghasemi

The medical imaging literature has witnessed remarkable progress in high-performing segmentation models based on convolutional neural networks. Despite the new performance highs, the recent advanced segmentation models still require large,…

Image and Video Processing · Electrical Eng. & Systems 2020-02-13 Nima Tajbakhsh , Laura Jeyaseelan , Qian Li , Jeffrey Chiang , Zhihao Wu , Xiaowei Ding

In computational pathology, automatic nuclei instance segmentation plays an essential role in whole slide image analysis. While many computerized approaches have been proposed for this task, supervised deep learning (DL) methods have shown…

Image and Video Processing · Electrical Eng. & Systems 2023-08-04 Amirreza Mahbod , Christine Polak , Katharina Feldmann , Rumsha Khan , Katharina Gelles , Georg Dorffner , Ramona Woitek , Sepideh Hatamikia , Isabella Ellinger

Automated cellular instance segmentation is a process utilized for accelerating biological research for the past two decades, and recent advancements have produced higher quality results with less effort from the biologist. Most current…

Computer Vision and Pattern Recognition · Computer Science 2023-01-02 Matthew Keaton , Ram Zaveri , Gianfranco Doretto

Cancer detection and classification from gigapixel whole slide images of stained tissue specimens has recently experienced enormous progress in computational histopathology. The limitation of available pixel-wise annotated scans shifted the…

Computer Vision and Pattern Recognition · Computer Science 2023-03-30 Mehdi Naouar , Gabriel Kalweit , Ignacio Mastroleo , Philipp Poxleitner , Marc Metzger , Joschka Boedecker , Maria Kalweit

Instance segmentation is a computer vision task where separate objects in an image are detected and segmented. State-of-the-art deep neural network models require large amounts of labeled data in order to perform well in this task. Making…

Computer Vision and Pattern Recognition · Computer Science 2022-02-21 Tuomas Sormunen , Arttu Lämsä , Miguel Bordallo Lopez

Multi-organ segmentation holds paramount significance in many clinical tasks. In practice, compared to large fully annotated datasets, multiple small datasets are often more accessible and organs are not labelled consistently. Normally, an…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Zhendi Gong , Susan Francis , Eleanor Cox , Stamatios N. Sotiropoulos , Dorothee P. Auer , Guoping Qiu , Andrew P. French , Xin Chen

Background: Chromosome karyotype analysis is crucial for diagnosing hereditary diseases, yet detecting structural abnormalities remains challenging. While AI has shown promise in medical imaging, its effectiveness varies across modalities.…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Ran Wei , ZhiXiong Lan , Qing Yan , Ning Song , Ming Lv , LongQing Ye

The quantification of biomarkers on immunohistochemistry breast cancer images is essential for defining appropriate therapy for breast cancer patients, as well as for extracting relevant information on disease prognosis. This is an arduous…

Image and Video Processing · Electrical Eng. & Systems 2023-11-27 Blanca Maria Priego-Torresa , Barbara Lobato-Delgado , Lidia Atienza-Cuevas , Daniel Sanchez-Morillo

Digital pathology has made significant advances in tumor diagnosis and segmentation, but image variability due to differences in organs, tissue preparation, and acquisition - known as domain shift - limits the effectiveness of current…

Image and Video Processing · Electrical Eng. & Systems 2024-09-23 Ho Heon Kim , Won Chan Jeong , Young Shin Ko , Young Jin Park

Precise delineation of multiple organs or abnormal regions in the human body from medical images plays an essential role in computer-aided diagnosis, surgical simulation, image-guided interventions, and especially in radiotherapy treatment…

Image and Video Processing · Electrical Eng. & Systems 2024-11-19 Shiman Li , Haoran Wang , Yucong Meng , Chenxi Zhang , Zhijian Song

Autonomous vehicles require knowledge of the surrounding road layout, which can be predicted by state-of-the-art CNNs. This work addresses the current lack of data for determining lane instances, which are needed for various driving…

Computer Vision and Pattern Recognition · Computer Science 2018-08-03 Brook Roberts , Sebastian Kaltwang , Sina Samangooei , Mark Pender-Bare , Konstantinos Tertikas , John Redford

Star-convex shapes arise across bio-microscopy and radiology in the form of nuclei, nodules, metastases, and other units. Existing instance segmentation networks for such structures train on densely labeled instances for each dataset, which…

Computer Vision and Pattern Recognition · Computer Science 2023-07-17 Neel Dey , S. Mazdak Abulnaga , Benjamin Billot , Esra Abaci Turk , P. Ellen Grant , Adrian V. Dalca , Polina Golland

Multi-annotator medical image segmentation is an important research problem, but requires annotated datasets that are expensive to collect. Dermoscopic skin lesion imaging allows human experts and AI systems to observe morphological…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Kumar Abhishek , Jeremy Kawahara , Ghassan Hamarneh

Chromosome analysis is vital for diagnosing genetic disorders and guiding cancer therapy decisions through the identification of somatic clonal aberrations. However, developing an AI model are hindered by the overwhelming complexity and…

Quantitative Methods · Quantitative Biology 2025-05-23 Changchun Yang , Weiqian Dai , Yilan Zhang , Siyuan Chen , Jingdong Hu , Junkai Su , Yuxuan Chen , Ao Xu , Na Li , Xin Gao , Yongguo Yu

Automatic medical image segmentation plays a critical role in scientific research and medical care. Existing high-performance deep learning methods typically rely on large training datasets with high-quality manual annotations, which are…

Image and Video Processing · Electrical Eng. & Systems 2021-11-17 Shanshan Wang , Cheng Li , Rongpin Wang , Zaiyi Liu , Meiyun Wang , Hongna Tan , Yaping Wu , Xinfeng Liu , Hui Sun , Rui Yang , Xin Liu , Jie Chen , Huihui Zhou , Ismail Ben Ayed , Hairong Zheng

The Instance Segmentation task, an extension of the well-known Object Detection task, is of great help in many areas, such as precision agriculture: being able to automatically identify plant organs and the possible diseases associated with…

Computer Vision and Pattern Recognition · Computer Science 2022-06-22 Leonardo Rossi , Marco Valenti , Sara Elisabetta Legler , Andrea Prati

Analysis of histopathology slides is a critical step for many diagnoses, and in particular in oncology where it defines the gold standard. In the case of digital histopathological analysis, highly trained pathologists must review vast…

Computer Vision and Pattern Recognition · Computer Science 2020-02-21 Pierre Courtiol , Eric W. Tramel , Marc Sanselme , Gilles Wainrib

Segmentation is essential for medical image analysis tasks such as intervention planning, therapy guidance, diagnosis, treatment decisions. Deep learning is becoming increasingly prominent for segmentation, where the lack of annotations,…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 Firat Ozdemir , Zixuan Peng , Christine Tanner , Philipp Fuernstahl , Orcun Goksel