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Light microscopy is a widespread and inexpensive imaging technique facilitating biomedical discovery and diagnostics. However, light diffraction barrier and imperfections in optics limit the level of detail of the acquired images. The…

Quantitative Methods · Quantitative Biology 2026-03-24 Rui Li , Gabriel della Maggiora , Vardan Andriasyan , Anthony Petkidis , Artsemi Yushkevich , Mikhail Kudryashev , Artur Yakimovich

In this paper, we present the Directly Denoising Diffusion Model (DDDM): a simple and generic approach for generating realistic images with few-step sampling, while multistep sampling is still preserved for better performance. DDDMs require…

Computer Vision and Pattern Recognition · Computer Science 2024-06-03 Dan Zhang , Jingjing Wang , Feng Luo

Denoising diffusion models have found applications in image segmentation by generating segmented masks conditioned on images. Existing studies predominantly focus on adjusting model architecture or improving inference, such as test-time…

Image and Video Processing · Electrical Eng. & Systems 2023-12-11 Yunguan Fu , Yiwen Li , Shaheer U Saeed , Matthew J Clarkson , Yipeng Hu

Recent advances in denoising diffusion probabilistic models have shown great success in image synthesis tasks. While there are already works exploring the potential of this powerful tool in image semantic segmentation, its application in…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Xinrong Hu , Yu-Jen Chen , Tsung-Yi Ho , Yiyu Shi

Magnetic resonance (MR) and computer tomography (CT) images are two typical types of medical images that provide mutually-complementary information for accurate clinical diagnosis and treatment. However, obtaining both images may be limited…

Image and Video Processing · Electrical Eng. & Systems 2023-06-02 Jiayuan Wang , Q. M. Jonathan Wu , Farhad Pourpanah

Traditional model-based image reconstruction (MBIR) methods combine forward and noise models with simple object priors. Recent application of deep learning methods for image reconstruction provides a successful data-driven approach to…

Image and Video Processing · Electrical Eng. & Systems 2022-05-20 Ling Chen , Zhishen Huang , Yong Long , Saiprasad Ravishankar

In the medical domain, acquiring large datasets is challenging due to both accessibility issues and stringent privacy regulations. Consequently, data availability and privacy protection are major obstacles to applying machine learning in…

Image and Video Processing · Electrical Eng. & Systems 2025-07-02 Wenwu Tang , Khaled Seyam , Bin Yang

In radiation therapy (RT), the reliance on pre-treatment computed tomography (CT) images encounter challenges due to anatomical changes, necessitating adaptive planning. Daily cone-beam CT (CBCT) imaging, pivotal for therapy adjustment,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-20 Joonil Hwang , Sangjoon Park , NaHyeon Park , Seungryong Cho , Jin Sung Kim

While supervised stereo matching and monocular depth estimation have advanced significantly with learning-based algorithms, self-supervised methods using stereo images as supervision signals have received relatively less focus and require…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Zihua Liu , Yizhou Li , Songyan Zhang , Masatoshi Okutomi

Cone-beam computed tomography (CBCT) is widely used for image-guided radiotherapy (IGRT). It provides real time visualization at low cost and dose. However, photon scattering and beam hindrance cause artifacts in CBCT. These include…

Medical Physics · Physics 2025-09-29 Alzahra Altalib , Chunhui Li , Alessandro Perelli

The pose-guided person image generation task requires synthesizing photorealistic images of humans in arbitrary poses. The existing approaches use generative adversarial networks that do not necessarily maintain realistic textures or need…

Computer Vision and Pattern Recognition · Computer Science 2023-03-02 Ankan Kumar Bhunia , Salman Khan , Hisham Cholakkal , Rao Muhammad Anwer , Jorma Laaksonen , Mubarak Shah , Fahad Shahbaz Khan

Radiomics is an active area of research in medical image analysis, the low reproducibility of radiomics has limited its applicability to clinical practice. This issue is especially prominent when radiomic features are calculated from noisy…

Quantitative Methods · Quantitative Biology 2021-08-16 Junhua Chen , Chong Zhang , Alberto Traverso , Ivan Zhovannik , Andre Dekker , Leonard Wee , Inigo Bermejo

Score-based diffusion models have significantly advanced generative deep learning for image processing. Measurement conditioned models have also been applied to inverse problems such as CT reconstruction. However, the conventional approach,…

Medical Physics · Physics 2025-02-24 Matthew Tivnan , Dufan Wu , Quanzheng Li

Computed Tomography (CT) imposes risk on the patients due to its inherent X-ray radiation, stimulating the development of low-dose CT (LDCT) imaging methods. Lowering the radiation dose reduces the health risks but leads to noisier…

Image and Video Processing · Electrical Eng. & Systems 2022-11-03 Elvira Zainulina , Alexey Chernyavskiy , Dmitry V. Dylov

Self-supervised image denoising techniques emerged as convenient methods that allow training denoising models without requiring ground-truth noise-free data. Existing methods usually optimize loss metrics that are calculated from multiple…

Low-Dose Computed Tomography (LDCT) technique, which reduces the radiation harm to human bodies, is now attracting increasing interest in the medical imaging field. As the image quality is degraded by low dose radiation, LDCT exams require…

Image and Video Processing · Electrical Eng. & Systems 2022-04-19 Liutao Yang , Zhongnian Li , Rongjun Ge , Junyong Zhao , Haipeng Si , Daoqiang Zhang

We propose a novel approach to denoising diffusion magnetic resonance images (dMRI) using convolutional neural networks, that exploits the benefits of data acquired at multiple b-values to offset the need for many redundant observations.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-23 Jakub Jurek , Andrzej Materka , Kamil Ludwisiak , Agata Majos , Filip Szczepankiewicz

Cloud removal (CR) remains a challenging task in remote sensing image processing. Although diffusion models (DM) exhibit strong generative capabilities, their direct applications to CR are suboptimal, as they generate cloudless images from…

Computer Vision and Pattern Recognition · Computer Science 2025-04-01 Yi Liu , Wengen Li , Jihong Guan , Shuigeng Zhou , Yichao Zhang

Brain MRI scans are often found in four modalities, consisting of T1-weighted with and without contrast enhancement (T1ce and T1w), T2-weighted imaging (T2w), and Flair. Leveraging complementary information from these different modalities…

Image and Video Processing · Electrical Eng. & Systems 2025-09-22 Bhavesh Sandbhor , Bheeshm Sharma , Balamurugan Palaniappan

Reducing scan times, radiation dose, and enhancing image quality for lower-performance scanners, are critical in low-dose PET imaging. Deep learning techniques have been investigated for PET image denoising. However, existing models have…