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Hyperdimensional Computing (HDC) offers a computationally efficient paradigm for neuromorphic learning. Yet, it lacks rigorous uncertainty quantification, leading to open decision boundaries and, consequently, vulnerability to outliers,…

Hyperdimensional computing (HDC) is a novel computational paradigm that operates on long-dimensional vectors known as hypervectors. The hypervectors are constructed as long bit-streams and form the basic building blocks of HDC systems. In…

Hardware Architecture · Computer Science 2023-11-21 Sercan Aygun , Mehran Shoushtari Moghadam , M. Hassan Najafi

This paper studies the geometry of binary hyperdimensional computing (HDC), a computational scheme in which data are encoded using high-dimensional binary vectors. We establish a result about the similarity structure induced by the HDC…

Machine Learning · Computer Science 2024-04-29 Saeid Pourmand , Wyatt D. Whiting , Alireza Aghasi , Nicholas F. Marshall

Hyperdimensional computing (HDC) is a promising approach for energy-efficient edge machine learning (ML), where low latency, low power, and tight memory budgets are essential. However, traditional HDC relies on symbolic binding and…

Hardware Architecture · Computer Science 2026-05-26 Sabrina Hassan Moon , Abu Kaisar Mohammad Masum , Sercan Aygun , Dayane Reis

By mimicking brain-like cognition and exploiting parallelism, hyperdimensional computing (HDC) classifiers have been emerging as a lightweight framework to achieve efficient on-device inference. Nonetheless, they have two fundamental…

Machine Learning · Computer Science 2022-04-04 Shijin Duan , Xiaolin Xu , Shaolei Ren

Ensemble learning is a classical learning method utilizing a group of weak learners to form a strong learner, which aims to increase the accuracy of the model. Recently, brain-inspired hyperdimensional computing (HDC) becomes an emerging…

Neural and Evolutionary Computing · Computer Science 2022-03-28 Ruixuan Wang , Dongning Ma , Xun Jiao

Brain-inspired hyperdimensional computing (HDC) has been recently considered a promising learning approach for resource-constrained devices. However, existing approaches use static encoders that are never updated during the learning…

Machine Learning · Computer Science 2023-04-13 Junyao Wang , Sitao Huang , Mohsen Imani

Hyperdimensional Computing (HDC) is an emerging computational framework that mimics important brain functions by operating over high-dimensional vectors, called hypervectors (HVs). In-memory computing implementations of HDC are desirable…

Emerging Technologies · Computer Science 2021-06-24 Arman Kazemi , Mohammad Mehdi Sharifi , Zhuowen Zou , Michael Niemier , X. Sharon Hu , Mohsen Imani

Hyperdimensional Computing (HDC) is a computationally and data-efficient paradigm that acts as a bridge between connectionist and symbolic approaches to artificial intelligence (AI). However, HDC's simplicity poses challenges for encoding…

Machine Learning · Computer Science 2026-05-28 Calvin Yeung , Zhuowen Zou , SungHeon Jeong , Wenjun Huang , Nathaniel D Bastian , Mohsen Imani

Decomposition is a proven way to shrink deep networks without changing input-output dimensionality or interface semantics. We bring this idea to hyperdimensional computing (HDC), where footprint cuts usually shrink the feature axis and…

Machine Learning · Computer Science 2026-02-04 Sanggeon Yun , Hyunwoo Oh , Ryozo Masukawa , Mohsen Imani

Learning accurate drug representations is essential for task such as computational drug repositioning. A drug hierarchy is a valuable source that encodes knowledge of relations among drugs in a tree-like structure where drugs that act on…

Biomolecules · Quantitative Biology 2022-08-15 Ke Yu , Shyam Visweswaran , Kayhan Batmanghelich

This paper presents a quantum algorithm for efficiently decoding hypervectors, a crucial process in extracting atomic elements from hypervectors - an essential task in Hyperdimensional Computing (HDC) models for interpretable learning and…

Quantum Physics · Physics 2024-06-19 Prathyush Poduval , Zhuowen Zou , Alvaro Velasquez , Mohsen Imani

Molecular representation learning is pivotal for various molecular property prediction tasks related to drug discovery. Robust and accurate benchmarks are essential for refining and validating current methods. Existing molecular property…

Chemical Physics · Physics 2024-06-27 Shikun Feng , Jiaxin Zheng , Yinjun Jia , Yanwen Huang , Fengfeng Zhou , Wei-Ying Ma , Yanyan Lan

Hyperdimensional computing (HDC) is an emerging computing paradigm that represents, manipulates, and communicates data using very long random vectors (aka hypervectors). Among different hardware platforms capable of executing HDC…

Hardware Architecture · Computer Science 2022-05-24 Robert Guirado , Abbas Rahimi , Geethan Karunaratne , Eduard Alarcón , Abu Sebastian , Sergi Abadal

Case-based Reasoning (CBR) on high-dimensional and heterogeneous data is a trending yet challenging and computationally expensive task in the real world. A promising approach is to obtain low-dimensional hash codes representing cases and…

Information Retrieval · Computer Science 2022-06-30 Qi Zhang , Liang Hu , Chongyang Shi , Ke Liu , Longbing Cao

Hyperdimensional computing (HDC) is an emerging computing paradigm with significant promise for efficient and robust learning. In HDC, objects are encoded with high-dimensional vector symbolic sequences called hypervectors. The quality of…

Machine Learning · Computer Science 2023-11-20 Sercan Aygun , M. Hassan Najafi

Molecular property prediction, crucial for early drug candidate screening and optimization, has seen advancements with deep learning-based methods. While deep learning-based methods have advanced considerably, they often fall short in fully…

Biomolecules · Quantitative Biology 2024-07-01 Taojie Kuang , Yiming Ren , Zhixiang Ren

Hyperdimensional computing (HDC) offers lightweight learning for energy-constrained devices by encoding data into high-dimensional vectors. However, its reliance on ultra-high dimensionality and static, randomly initialized hypervectors…

Machine Learning · Computer Science 2026-02-03 Hanne Dejonghe , Sam Leroux

Hyperdimensional (HD) computing is built upon its unique data type referred to as hypervectors. The dimension of these hypervectors is typically in the range of tens of thousands. Proposed to solve cognitive tasks, HD computing aims at…

Machine Learning · Computer Science 2020-06-08 Lulu Ge , Keshab K. Parhi

Predicting how a drug-like molecule binds to a specific protein target is a core problem in drug discovery. An extremely fast computational binding method would enable key applications such as fast virtual screening or drug engineering.…

Biomolecules · Quantitative Biology 2022-06-07 Hannes Stärk , Octavian-Eugen Ganea , Lagnajit Pattanaik , Regina Barzilay , Tommi Jaakkola