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Misclassified variables used in regression models, either as a covariate or as the response, may lead to biased estimators and incorrect inference. Even though Bayesian models to adjust for misclassification error exist, it has not been…

Methodology · Statistics 2024-11-26 Emma Skarstein , Leonardo Soares Bastos , Håvard Rue , Stefanie Muff

Spatio-temporal Bayesian inference drives environmental and health sciences using latent Gaussian models. Integrated Nested Laplace Approximations (INLA) enable inference for these models at HPC scale but rely on derivative-based…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-08 Afif Boudaoud , Lisa Gaedke-Merzhäuser , Alexandros Nikolaos Ziogas , Vincent Maillou , Alexandru Calotoiu , Marcin Copik , Håvard Rue , Mathieu Luisier , Torsten Hoefler

The goal of phylodynamics, an area on the intersection of phylogenetics and population genetics, is to reconstruct population size dynamics from genetic data. Recently, a series of nonparametric Bayesian methods have been proposed for such…

Applications · Statistics 2012-10-19 Julia A. Palacios , Vladimir N. Minin

Recently, it has been shown that approximations to marginal posterior distributions obtained using a low discrepancy sequence (LDS) can outperform standard grid-based methods with respect to both accuracy and computational efficiency. This…

Computation · Statistics 2019-12-05 Paul T. Brown , Chaitanya Joshi , Stephen Joe , Haavard Rue

The integrated nested Laplace approximation (INLA) is a well-known and popular technique for spatial modeling with a user-friendly interface in the R-INLA package. Unfortunately, only a certain class of latent Gaussian models are amenable…

Methodology · Statistics 2021-03-19 Aaron Osgood-Zimmerman , Jon Wakefield

Modeling longitudinal and survival data jointly offers many advantages such as addressing measurement error and missing data in the longitudinal processes, understanding and quantifying the association between the longitudinal markers and…

Robust time series analysis is an important subject in statistical modeling. Models based on Gaussian distribution are sensitive to outliers, which may imply in a significant degradation in estimation performance as well as in prediction…

Background: We aimed to design a Bayesian adaption trial through extensive simulations to determine values for key design parameters, demonstrate error rates, and establish the expected sample size. The complexity of the proposed outcome…

To account for measurement error (ME) in explanatory variables, Bayesian approaches provide a flexible framework, as expert knowledge about unobserved covariates can be incorporated in the prior distributions. However, given the analytic…

Methodology · Statistics 2013-08-19 Stefanie Muff , Andrea Riebler , Havard Rue , Philippe Saner , Leonhard Held

This paper proposes a two-stage estimation approach for a spatial misalignment scenario that is motivated by the epidemiological problem of linking pollutant exposures and health outcomes. We use the integrated nested Laplace approximation…

Methodology · Statistics 2022-07-21 Stephen Jun Villejo , Janine B Illian , Ben Swallow

We address in this paper a new approach for fitting spatiotemporal models with application in disease mapping using the interaction types 1,2,3, and 4. When we account for the spatiotemporal interactions in disease-mapping models, inference…

Methodology · Statistics 2022-06-22 Esmail Abdul Fattah , Haavard Rue

Bayesian inference often relies on Markov chain Monte Carlo (MCMC) methods, particularly required for non-Gaussian data families. When dealing with complex hierarchical models, the MCMC approach can be computationally demanding in workflows…

Applications · Statistics 2026-03-31 Esmail Abdul Fattah , Elias Krainski , Havard Rue

Current implementations of multiresolution methods are limited in terms of possible types of responses and approaches to inference. We provide a multiresolution approach for spatial analysis of non-Gaussian responses using latent Gaussian…

Methodology · Statistics 2020-05-27 John Paige , Geir-Arne Fuglstad , Andrea Riebler , Jon Wakefield

The INLA package provides a tool for computationally efficient Bayesian modeling and inference for various widely used models, more formally the class of latent Gaussian models. It is a non-sampling based framework which provides…

Methodology · Statistics 2019-07-26 Janet van Niekerk , Haakon Bakka , Haavard Rue , Olaf Schenk

We propose a spatio-temporal data-fusion framework for point data and gridded data with variables observed on different spatial supports. A latent Gaussian field with a Mat\'ern-SPDE prior provides a continuous space representation, while…

Methodology · Statistics 2025-11-19 Weiyue Zheng , Andrew Elliott , Claire Miller , Marian Scott

This paper introduces a Laplace approximation to Bayesian inference in Dirichlet regression models, which can be used to analyze a set of variables on a simplex exhibiting skewness and heteroscedasticity, without having to transform the…

We introduce a new copula-based correction for generalized linear mixed models (GLMMs) within the integrated nested Laplace approximation (INLA) approach for approximate Bayesian inference for latent Gaussian models. While INLA is usually…

Computation · Statistics 2015-12-16 Egil Ferkingstad , Håvard Rue

We propose the approximate Laplace approximation (ALA) to evaluate integrated likelihoods, a bottleneck in Bayesian model selection. The Laplace approximation (LA) is a popular tool that speeds up such computation and equips strong model…

Computation · Statistics 2021-10-07 David Rossell , Oriol Abril , Anirban Bhattacharya

This tutorial shows how various Bayesian survival models can be fitted using the integrated nested Laplace approximation in a clear, legible, and comprehensible manner using the INLA and INLAjoint R-packages. Such models include accelerated…

Efficient Bayesian inference remains a computational challenge in hierarchical models. Simulation-based approaches such as Markov Chain Monte Carlo methods are still popular but have a large computational cost. When dealing with the large…

Computation · Statistics 2021-12-07 Cristian Chiuchiolo , Janet van Niekerk , Haavard Rue