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Clinical tracking systems are popular but typically require specific tracking markers. During the last years, scanning speed of optical coherence tomography (OCT) has increased to A-scan rates above 1 MHz allowing to acquire volume scans of…

Medical Physics · Physics 2019-01-15 Matthias Schlüter , Christoph Otte , Thore Saathoff , Nils Gessert , Alexander Schlaefer

Disease complications can alter vascular network morphology and disrupt tissue functioning. Diabetic retinopathy, for example, is a complication of types 1 and 2 diabetes mellitus that can cause blindness. Microvascular diseases are…

Quantitative Methods · Quantitative Biology 2022-09-13 John T. Nardini , Charles W. J. Pugh , Helen M. Byrne

This study introduces a novel unsupervised medical image feature extraction method that employs spatial stratification techniques. An objective function based on weight is proposed to achieve the purpose of fast image recognition. The…

Image and Video Processing · Electrical Eng. & Systems 2024-06-28 Qishi Zhan , Dan Sun , Erdi Gao , Yuhan Ma , Yaxin Liang , Haowei Yang

Diagnosing different retinal diseases from Spectral Domain Optical Coherence Tomography (SD-OCT) images is a challenging task. Different automated approaches such as image processing, machine learning and deep learning algorithms have been…

Image and Video Processing · Electrical Eng. & Systems 2020-05-19 Sharif Amit Kamran , Sourajit Saha , Ali Shihab Sabbir , Alireza Tavakkoli

Classical semantic segmentation methods, including the recent deep learning ones, assume that all classes observed at test time have been seen during training. In this paper, we tackle the more realistic scenario where unexpected objects of…

Computer Vision and Pattern Recognition · Computer Science 2019-04-18 Krzysztof Lis , Krishna Nakka , Pascal Fua , Mathieu Salzmann

Deep unsupervised approaches are gathering increased attention for applications such as pathology detection and segmentation in medical images since they promise to alleviate the need for large labeled datasets and are more generalizable…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Ioannis Lagogiannis , Felix Meissen , Georgios Kaissis , Daniel Rueckert

Modern deep unsupervised learning methods have shown great promise for detecting diseases across a variety of medical imaging modalities. While previous generative modeling approaches successfully perform anomaly detection by learning the…

Image and Video Processing · Electrical Eng. & Systems 2021-03-26 Alex Chang , Vinith Suriyakumar , Abhishek Moturu , James Tu , Nipaporn Tewattanarat , Sayali Joshi , Andrea Doria , Anna Goldenberg

Identifying important biomarkers that are predictive for cancer patients' prognosis is key in gaining better insights into the biological influences on the disease and has become a critical component of precision medicine. The emergence of…

Methodology · Statistics 2016-03-22 Hyokyoung Grace Hong , Jian Kang , Yi Li

With the advent of smartphone indirect ophthalmoscopy, teleophthalmology - the use of specialist ophthalmology assets at a distance from the patient - has experienced a breakthrough, promising enormous benefits especially for healthcare in…

Computer Vision and Pattern Recognition · Computer Science 2019-03-08 Chris von Csefalvay

Bacterial heterogeneity is pivotal for adaptation to diverse environments, posing significant challenges in microbial diagnostics and therapeutic interventions. Recent advancements in high-resolution optical microscopy have revolutionized…

Biological Physics · Physics 2025-01-06 Dohyeon Lee , Hyun-Seung Lee , Moosung Lee , Minhee Kang , Geon Kim , Tae Yeul Kim , Nam Yong Lee , YongKeun Park

Retinal microaneurysms are the earliest clinical sign of diabetic retinopathy disease. Detection of microaneurysms is crucial for the early diagnosis of diabetic retinopathy and prevention of blindness. In this paper, a novel and reliable…

Computer Vision and Pattern Recognition · Computer Science 2018-05-09 Behdad Dashtbozorg , Jiong Zhang , Bart M. ter Haar Romeny

We address the problem of discovering part segmentations of articulated objects without supervision. In contrast to keypoints, part segmentations provide information about part localizations on the level of individual pixels. Capturing both…

Computer Vision and Pattern Recognition · Computer Science 2020-09-11 Sandro Braun , Patrick Esser , Björn Ommer

Automatic analysis of retinal blood images is of vital importance in diagnosis tasks of retinopathy. Segmenting vessels accurately is a fundamental step in analysing retinal images. However, it is usually difficult due to various imaging…

Computer Vision and Pattern Recognition · Computer Science 2019-02-12 Yishuo Zhang , Albert C. S. Chung

Robust and accurate detection and segmentation of heterogenous tumors appearing in different anatomical organs with supervised methods require large-scale labeled datasets covering all possible types of diseases. Due to the unavailability…

Computer Vision and Pattern Recognition · Computer Science 2023-05-23 Mehdi Astaraki , Francesca De Benetti , Yousef Yeganeh , Iuliana Toma-Dasu , Örjan Smedby , Chunliang Wang , Nassir Navab , Thomas Wendler

Age-related macular degeneration (AMD) is one of the leading causes of permanent vision loss in people aged over 60 years. Accurate segmentation of biomarkers such as drusen that points to the early stages of AMD is crucial in preventing…

Image and Video Processing · Electrical Eng. & Systems 2021-02-09 Tinu Theckel Joy , Suman Sedai , Rahil Garnavi

In the fast-evolving field of artificial intelligence, where models are increasingly growing in complexity and size, the availability of labeled data for training deep learning models has become a significant challenge. Addressing complex…

Computer Vision and Pattern Recognition · Computer Science 2026-02-19 Santiago C. Vilabella , Pablo Pérez-Núñez , Beatriz Remeseiro

Unsupervised object discovery aims to localize objects in images, while removing the dependence on annotations required by most deep learning-based methods. To address this problem, we propose a fully unsupervised, bottom-up approach, for…

Computer Vision and Pattern Recognition · Computer Science 2022-12-21 Sandra Kara , Hejer Ammar , Florian Chabot , Quoc-Cuong Pham

A comprehensive assessment of retinal health demands reliable and precise methods to measure localized blood perfusion. Despite considerable advancements in imaging techniques, such as indocyanine green and fluorescein angiography, along…

Medical Physics · Physics 2024-03-15 Michael Atlan

We propose a new fast fully unsupervised method to discover semantic patterns. Our algorithm is able to hierarchically find visual categories and produce a segmentation mask where previous methods fail. Through the modeling of what is a…

Computer Vision and Pattern Recognition · Computer Science 2021-02-25 Francesco Pelosin , Andrea Gasparetto , Andrea Albarelli , Andrea Torsello

Optical coherence tomography (OCT) captures cross-sectional data and is used for the screening, monitoring, and treatment planning of retinal diseases. Technological developments to increase the speed of acquisition often results in systems…

Image and Video Processing · Electrical Eng. & Systems 2023-01-03 Timothy T. Yu , Da Ma , Jayden Cole , Myeong Jin Ju , Mirza F. Beg , Marinko V. Sarunic