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Learning and decision making in the brain are key processes critical to survival, and yet are processes implemented by non-ideal biological building blocks which can impose significant error. We explore quantitatively how the brain might…

Neurons and Cognition · Quantitative Biology 2011-04-19 Jake Bouvrie , Jean-Jacques Slotine

We construct and investigate Boolean networks that follow a given reliable trajectory in state space, which is insensitive to fluctuations in the updating schedule, and which is also robust against noise. Robustness is quantified as the…

Biological Physics · Physics 2010-12-02 Christoph Schmal , Tiago P. Peixoto , Barbara Drossel

Noisy fluctuations are ubiquitous in complex systems. They play a crucial or delicate role in the dynamical evolution of gene regulation, signal transduction, biochemical reactions, among other systems. Therefore, it is essential to…

Dynamical Systems · Mathematics 2018-11-05 Jinqiao Duan , Hui Wang

Diverse biological networks exhibit universal features distinguished from those of random networks, calling much attention to their origins and implications. Here we propose a minimal evolution model of Boolean regulatory networks, which…

Molecular Networks · Quantitative Biology 2014-11-26 Deok-Sun Lee

The interaction between natural selection and random mutation is frequently debated in recent years. Does similar dilemma also exist in the evolution of real networks such as biological networks? In this paper, we try to discuss this issue…

Statistical Mechanics · Physics 2009-01-07 Zhen Shao , Hai-jun Zhou

Phenotype of biological systems needs to be robust against mutation in order to sustain themselves between generations. On the other hand, phenotype of an individual also needs to be robust against fluctuations of both internal and external…

Populations and Evolution · Quantitative Biology 2015-06-26 Kunihiko Kaneko

Biological networks such as gene regulatory networks possess desirable properties. They are more robust and controllable than random networks. This motivates the search for structural and dynamical features that evolution has incorporated…

Molecular Networks · Quantitative Biology 2024-02-16 Claus Kadelka , David Murrugarra

Neural codes appear efficient. Naturally, neuroscientists contend that an efficient process is responsible for generating efficient codes. They argue that natural selection is the efficient process that generates those codes. Although…

Neurons and Cognition · Quantitative Biology 2022-03-21 Han Kim

Over the last decade, significant progress has been made in understanding complex biological systems, however there have been few attempts at incorporating this knowledge into nature inspired optimization algorithms. In this paper, we…

Neural and Evolutionary Computing · Computer Science 2009-07-03 James M. Whitacre , Ruhul A. Sarker , Q. Tuan Pham

Engineered systems are designed to deftly operate under predetermined conditions yet are notoriously fragile when unexpected perturbations arise. In contrast, biological systems operate in a highly flexible manner; learn quickly adequate…

Adaptation and Self-Organizing Systems · Physics 2011-01-24 James M Whitacre , Philipp Rohlfshagen , Axel Bender , Xin Yao

Species or population that proliferate faster than others become dominant in numbers. Catalysis allows catalytic sets within a molecular reaction network to dominate the non catalytic parts of the network by processing most of the available…

Cell Behavior · Quantitative Biology 2016-08-31 Rudolf Hanel

When a biological system robustly corrects component-level errors, the direct pressure on component performance declines. Components may become less reliable, maintain more genetic variability, or drift neutrally in design, creating the…

Populations and Evolution · Quantitative Biology 2023-12-27 Steven A. Frank

A quantum computer -- i.e., a computer capable of manipulating data in quantum superposition -- would find applications including factoring, quantum simulation and tests of basic quantum theory. Since quantum superpositions are fragile, the…

Quantum Physics · Physics 2007-05-23 Ben W. Reichardt

Biological systems rely on robust internal information processing: Survival depends on highly reproducible dynamics of regulatory processes. Biological information processing elements, however, are intrinsically noisy (genetic switches,…

Molecular Networks · Quantitative Biology 2009-11-10 Konstantin Klemm , Stefan Bornholdt

Experience shows that typical evolutionary algorithms can cope well with stochastic disturbances such as noisy function evaluations. In this first mathematical runtime analysis of the $(1+\lambda)$ and $(1,\lambda)$ evolutionary algorithms…

Neural and Evolutionary Computing · Computer Science 2024-07-17 Denis Antipov , Benjamin Doerr , Alexandra Ivanova

This paper presents the foundation for a decomposition theory for Boolean networks, a type of discrete dynamical system that has found a wide range of applications in the life sciences, engineering, and physics. Given a Boolean network…

Dynamical Systems · Mathematics 2022-06-10 Claus Kadelka , Reinhard Laubenbacher , David Murrugarra , Alan Veliz-Cuba , Matthew Wheeler

Boolean networks with canalizing functions are used to model gene regulatory networks. In order to learn how such networks may behave under evolutionary forces, we simulate the evolution of a single Boolean network by means of an adaptive…

Populations and Evolution · Quantitative Biology 2011-11-09 Agnes Szejka , Barbara Drossel

Recent research has provided a wealth of evidence highlighting the pivotal role of high-order interdependencies in supporting the information-processing capabilities of distributed complex systems. These findings may suggest that high-order…

Adaptation and Self-Organizing Systems · Physics 2023-05-24 Patricio Orio , Pedro A. M. Mediano , Fernando E. Rosas

Different subsystems of organisms adapt over many time scales, such as rapid changes in the nervous system (learning), slower morphological and neurological change over the lifetime of the organism (postnatal development), and change over…

Neural and Evolutionary Computing · Computer Science 2017-07-28 Sam Kriegman , Nick Cheney , Francesco Corucci , Josh C. Bongard

The relevance of chaos to evolution is discussed in the context of the origin and maintenance of diversity and complexity. Evolution to the edge of chaos is demonstrated in an imitation game. As an origin of diversity, dynamic clustering of…

adap-org · Physics 2008-02-03 Kunihiko Kaneko