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Cell instance segmentation in Pap smear image remains challenging due to the wide existence of occlusion among translucent cytoplasm in cell clumps. Conventional methods heavily rely on accurate nuclei detection results and are easily…

Computer Vision and Pattern Recognition · Computer Science 2019-08-20 Yanning Zhou , Hao Chen , Jiaqi Xu , Qi Dou , Pheng-Ann Heng

Accurately segmenting and individualizing cells in SEM images is a highly promising technique for elucidating tissue architecture in oncology. While current AI-based methods are effective, errors persist, necessitating time-consuming manual…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Florian Robert , Alexia Calovoulos , Laurent Facq , Fanny Decoeur , Etienne Gontier , Christophe F. Grosset , Baudouin Denis de Senneville

Cell instance segmentation in fluorescence microscopy images is becoming essential for cancer dynamics and prognosis. Data extracted from cancer dynamics allows to understand and accurately model different metabolic processes such as…

Skin lesion segmentation is a crucial step in the computer-aided diagnosis of dermoscopic images. In the last few years, deep learning based semantic segmentation methods have significantly advanced the skin lesion segmentation results.…

Image and Video Processing · Electrical Eng. & Systems 2020-08-20 Yaxiong Wang , Yunchao Wei , Xueming Qian , Li Zhu , Yi Yang

Accurate segmenting nuclei instances is a crucial step in computer-aided image analysis to extract rich features for cellular estimation and following diagnosis as well as treatment. While it still remains challenging because the wide…

Computer Vision and Pattern Recognition · Computer Science 2019-03-14 Yanning Zhou , Omer Fahri Onder , Qi Dou , Efstratios Tsougenis , Hao Chen , Pheng-Ann Heng

Medical image segmentation, particularly in multi-domain scenarios, requires precise preservation of anatomical structures across diverse representations. While deep learning has advanced this field, existing models often struggle with…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Afshin Bozorgpour , Sina Ghorbani Kolahi , Reza Azad , Ilker Hacihaliloglu , Dorit Merhof

Nuclear segmentation in histology images is a challenging task due to significant variations in the shape and appearance of nuclei. One of the main hurdles in nuclear instance segmentation is overlapping nuclei where a smart algorithm is…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Navid Alemi Koohbanani , Mostafa Jahanifar , Ali Gooya , Nasir Rajpoot

We present a conceptually simple framework for object instance segmentation called Contour Proposal Network (CPN), which detects possibly overlapping objects in an image while simultaneously fitting closed object contours using an…

Computer Vision and Pattern Recognition · Computer Science 2021-04-09 Eric Upschulte , Stefan Harmeling , Katrin Amunts , Timo Dickscheid

Due to cellular heterogeneity, cell nuclei classification, segmentation, and detection from pathological images are challenging tasks. In the last few years, Deep Convolutional Neural Networks (DCNN) approaches have been shown…

Computer Vision and Pattern Recognition · Computer Science 2018-11-09 Md Zahangir Alom , Chris Yakopcic , Tarek M. Taha , Vijayan K. Asari

Accurate nuclei segmentation in microscopy whole slide images (WSIs) remains challenging due to variability in staining, imaging conditions, and tissue morphology. We propose CellGenNet, a knowledge distillation framework for robust…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Srijan Ray , Bikesh K. Nirala , Jason T. Yustein , Sundaresh Ram

Gland segmentation is a critical step to quantitatively assess the morphology of glands in histopathology image analysis. However, it is challenging to separate densely clustered glands accurately. Existing deep learning-based approaches…

Image and Video Processing · Electrical Eng. & Systems 2021-10-28 Haotian Wang , Min Xian , Aleksandar Vakanski

Identify the cells' nuclei is the important point for most medical analyses. To assist doctors finding the accurate cell' nuclei location automatically is highly demanded in the clinical practice. Recently, fully convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2019-11-25 Tianyang Zhang , Rui Ma

Polyp segmentation is of great importance in the early diagnosis and treatment of colorectal cancer. Since polyps vary in their shape, size, color, and texture, accurate polyp segmentation is very challenging. One promising way to mitigate…

Image and Video Processing · Electrical Eng. & Systems 2022-01-21 Zijin Yin , Kongming Liang , Zhanyu Ma , Jun Guo

Nucleus segmentation is an important task in medical image analysis. However, machine learning models cannot perform well because there are large amount of clusters of crowded nuclei. To handle this problem, existing approaches typically…

Computer Vision and Pattern Recognition · Computer Science 2020-06-05 Shengcong Chen , Changxing Ding , Dacheng Tao

Detection of colon polyps has become a trending topic in the intersecting fields of machine learning and gastrointestinal endoscopy. The focus has mainly been on per-frame classification. More recently, polyp segmentation has gained…

Image and Video Processing · Electrical Eng. & Systems 2021-07-02 Vajira Thambawita , Steven A. Hicks , Pål Halvorsen , Michael A. Riegler

Automatic cell segmentation is an essential step in the pipeline of computer-aided diagnosis (CAD), such as the detection and grading of breast cancer. Accurate segmentation of cells can not only assist the pathologists to make a more…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Muyi Sun , Zeyi Yao , Guanhong Zhang

Segmenting highly-overlapping objects is challenging, because typically no distinction is made between real object contours and occlusion boundaries. Unlike previous two-stage instance segmentation methods, we model image formation as…

Computer Vision and Pattern Recognition · Computer Science 2021-03-24 Lei Ke , Yu-Wing Tai , Chi-Keung Tang

This study addresses critical gaps in automated lymphoma segmentation from PET/CT images, focusing on issues often overlooked in existing literature. While deep learning has been applied for lymphoma lesion segmentation, few studies…

Weakly supervised nuclei segmentation is a critical problem for pathological image analysis and greatly benefits the community due to the significant reduction of labeling cost. Adopting point annotations, previous methods mostly rely on…

Image and Video Processing · Electrical Eng. & Systems 2022-02-14 Weizhen Liu , Qian He , Xuming He

We propose a deep clustering architecture alongside image segmentation for medical image analysis. The main idea is based on unsupervised learning to cluster images on severity of the disease in the subject's sample, and this image is then…

Image and Video Processing · Electrical Eng. & Systems 2020-05-28 Sharmin Pathan , Anant Tripathi
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