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Gliomas, a common type of malignant brain tumor, present significant surgical challenges due to their similarity to healthy tissue. Preoperative Magnetic Resonance Imaging (MRI) images are often ineffective during surgery due to factors…
Background: Accurate diagnosis of skull base tumors is essential for providing personalized surgical treatment strategies. Intraoperative diagnosis can be challenging due to tumor diversity and lack of intraoperative pathology resources.…
The efficiency of deep machine learning for automatic delineation of tumor areas has been demonstrated for intraoperative neuronavigation using active IR-mapping with the use of the cold test. The proposed approach employs a matrix…
Today, intensity-modulated radiation therapy (IMRT) is one of the methods used to treat brain tumors. In conventional treatment planning methods, after identifying planning target volume (PTV), and organs at risk (OARs), and determining the…
In this study, an automated three dimensional (3D) deep segmentation approach for detecting gliomas in 3D pre-operative MRI scans is proposed. Then, a classi-fication algorithm based on random forests, for survival prediction is presented.…
The majority of primary Central Nervous System (CNS) tumors in the brain are among the most aggressive diseases affecting humans. Early detection of brain tumor types, whether benign or malignant, glial or non-glial, is critical for cancer…
Complete resection of malignant gliomas is hampered by the difficulty in distinguishing tumor cells at the infiltration zone. Fluorescence guidance with 5-ALA assists in reaching this goal. Using hyperspectral imaging, previous work…
Acute lymphoblastic leukemia (ALL) is a prevalent hematological malignancy in both pediatric and adult populations. Early and accurate detection with precise subtyping is essential for guiding therapy. Conventional workflows are complex,…
DSC-MRI perfusion is a medical imaging technique for diagnosing and prognosing brain tumors and strokes. Its analysis relies on mathematical deconvolution, but noise or motion artifacts in a clinical environment can disrupt this process,…
Glaucoma is a chronic eye disease characterized by optic neuropathy, leading to irreversible vision loss. It progresses gradually, often remaining undiagnosed until advanced stages. Early detection is crucial to monitor atrophy and develop…
In malignant primary brain tumors, cancer cells infiltrate into the peritumoral brain structures which results in inevitable recurrence. Quantitative assessment of infiltrative heterogeneity in the peritumoral region, the area where biopsy…
Acute Lymphoblastic Leukemia (ALL) is one of the most common types of childhood blood cancer. The quick start of the treatment process is critical to saving the patient's life, and for this reason, early diagnosis of this disease is…
MRI analysis takes central position in brain tumor diagnosis and treatment, thus it's precise evaluation is crucially important. However, it's 3D nature imposes several challenges, so the analysis is often performed on 2D projections that…
Automatic segmentation is essential for the brain tumor diagnosis, disease prognosis, and follow-up therapy of patients with gliomas. Still, accurate detection of gliomas and their sub-regions in multimodal MRI is very challenging due to…
Melanoma detection is vital for early diagnosis and effective treatment. While deep learning models on dermoscopic images have shown promise, they require specialized equipment, limiting their use in broader clinical settings. This study…
Brain tumors are serious health problems that require early diagnosis due to their high mortality rates. Diagnosing tumors by examining Magnetic Resonance Imaging (MRI) images is a process that requires expertise and is prone to error.…
Glioma is a common malignant brain tumor with distinct survival among patients. The isocitrate dehydrogenase (IDH) gene mutation provides critical diagnostic and prognostic value for glioma. It is of crucial significance to non-invasively…
Recent studies have shown promising results in using Deep Learning to detect malignancy in whole slide imaging. However, they were limited to just predicting positive or negative finding for a specific neoplasm. We attempted to use Deep…
Vision transformers (ViT) have been shown to allow for more flexible feature detection and can outperform convolutional neural network (CNN) when pre-trained on sufficient data. Due to their promising feature detection capabilities, we…
Retinoblastoma is the most prominent childhood primary intraocular malignancy that impacts the vision of children and adults worldwide. In contrasting and comparing with adults it is uveal melanoma. It is an aggressive tumor that can fill…