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Intraclass correlation in bilateral data has been investigated in recent decades with various statistical methods. In practice, stratifying bilateral data by some control variables will provide more sophisticated statistical results to…

Methodology · Statistics 2023-03-24 Wanqing Tian , Chang-Xing Ma

In clinical trials studying paired parts of a subject with binary outcomes, it is expected to collect measurements bilaterally. However, there are cases where subjects contribute measurements for only one part. By utilizing combined data,…

Applications · Statistics 2024-03-06 Shuyi Liang , Kai-Tai Fang , Xin-Wei Huang , Yijing Xin , Chang-Xing Ma

Introduction: estimation of confidence intervals (CIs) of binomial proportions has been reviewed more than once but the directional interpretation, distinguishing the overestimation from the underestimation, was neglected while the sample…

Other Statistics · Statistics 2021-03-22 André Gillibert , Jacques Bénichou , Bruno Falissard

There are over 55 different ways to construct a confidence respectively credible interval (CI) for the binomial proportion. Methods to compare them are necessary to decide which should be used in practice. The interval score has been…

Methodology · Statistics 2022-07-08 Lisa J. Hofer , Leonhard Held

Stratification is commonly employed in clinical trials to reduce the chance covariate imbalances and increase the precision of the treatment effect estimate. We propose a general framework for constructing the confidence interval (CI) for a…

Methodology · Statistics 2021-10-26 Yongqiang Tang

Measurements are generally collected as unilateral or bilateral data in clinical trials or observational studies. For example, in ophthalmology studies, the primary outcome is often obtained from one eye or both eyes of an individual. In…

Methodology · Statistics 2021-11-01 Kejia Wang , Chang-Xing Ma

Confidence intervals are a fundamental tool for quantifying the uncertainty of parameters of interest. With the increase of data privacy awareness, developing a private version of confidence intervals has gained growing attention from both…

Methodology · Statistics 2024-04-12 Shurong Lin , Mark Bun , Marco Gaboardi , Eric D. Kolaczyk , Adam Smith

A generalization of the classical concordance correlation coefficient (CCC) is considered under a three-level design where multiple raters rate every subject over time, and each rater is rating every subject multiple times at each measuring…

Methodology · Statistics 2025-04-15 Soumya Sahu , Thomas Mathew , Dulal K. Bhaumik

When assessing the quality of prediction models in machine learning, confidence intervals (CIs) for the generalization error, which measures predictive performance, are a crucial tool. Luckily, there exist many methods for computing such…

We propose and study three confidence intervals (CIs) centered at an estimator that is intentionally biased to reduce mean squared error. The first CI simply uses an unbiased estimator's standard error; compared to centering at the unbiased…

Econometrics · Economics 2025-02-04 David M. Kaplan , Xin Liu

Small sample sizes in clinical studies arises from factors such as reduced costs, limited subject availability, and the rarity of studied conditions. This creates challenges for accurately calculating confidence intervals (CIs) using the…

Methodology · Statistics 2025-11-11 Mulan Wu , Mengyu Xu , Dongyun Kim

Confidence intervals (CIs) are instrumental in statistical analysis, providing a range estimate of the parameters. In modern statistics, selective inference is common, where only certain parameters are highlighted. However, this selective…

Methodology · Statistics 2025-09-17 Tzviel Frostig , Yoav Benjamini , Ruth Heller

This paper concerns the construction of confidence intervals in standard seroprevalence surveys. In particular, we discuss methods for constructing confidence intervals for the proportion of individuals in a population infected with a…

Applications · Statistics 2021-10-05 Thomas J. DiCiccio , David M. Ritzwoller , Joseph P. Romano , Azeem M. Shaikh

We study the statistical properties of an estimator derived by applying a gradient ascent method with multiple initializations to a multi-modal likelihood function. We derive the population quantity that is the target of this estimator and…

Statistics Theory · Mathematics 2022-01-04 Yen-Chi Chen

This paper proposes a decorrelation-based approach to test hypotheses and construct confidence intervals for the low dimensional component of high dimensional proportional hazards models. Motivated by the geometric projection principle, we…

Machine Learning · Statistics 2014-12-17 Ethan X. Fang , Yang Ning , Han Liu

In certain privacy-sensitive scenarios within fields such as clinical trial simulations, federated learning, and distributed learning, researchers often face the challenge of estimating correlations between variables without access to…

Methodology · Statistics 2025-08-05 Longwen Shang , Min Tsao , Xuekui Zhang

This paper introduces Conformal Thresholded Intervals (CTI), a novel conformal regression method that aims to produce the smallest possible prediction set with guaranteed coverage. Unlike existing methods that rely on nested conformal…

Machine Learning · Computer Science 2025-01-03 Rui Luo , Zhixin Zhou

Any supervised machine learning analysis is required to provide an estimate of the out-of-sample predictive performance. However, it is imperative to also provide a quantification of the uncertainty of this performance in the form of a…

Machine Learning · Computer Science 2024-06-13 Konstantinos Paraschakis , Andrea Castellani , Giorgos Borboudakis , Ioannis Tsamardinos

Concentration inequalities have become increasingly popular in machine learning, probability, and statistical research. Using concentration inequalities, one can construct confidence intervals (CIs) for many quantities of interest.…

Statistics Theory · Mathematics 2019-03-06 Hien D. Nguyen

Introductory texts on statistics typically only cover the classical "two sigma" confidence interval for the mean value and do not describe methods to obtain confidence intervals for other estimators. The present technical report fills this…

Methodology · Statistics 2018-07-11 Christoph Dalitz
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