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Medical image segmentation is vital for modern healthcare and is a key element of computer-aided diagnosis. While recent advancements in computer vision have explored unsupervised segmentation using pre-trained models, these methods have…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Mosong Ma , Tania Stathaki , Michalis Lazarou

The rapid progress of multimodal large language models (MLLMs) has led to increasing interest in agent-based systems. While most prior work in medical imaging concentrates on automating routine clinical workflows, we study an underexplored…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Zihao Zhao , Frederik Hauke , Juliana De Castilhos , Sven Nebelung , Daniel Truhn

Medical imaging is an essential tool for diagnosing various healthcare diseases and conditions. However, analyzing medical images is a complex and time-consuming task that requires expertise and experience. This article aims to design a…

Image and Video Processing · Electrical Eng. & Systems 2023-05-15 Ayyub Alzahem , Shahid Latif , Wadii Boulila , Anis Koubaa

Artificial Intelligence in Medicine has made significant progress with emerging applications in medical imaging, patient care, and other areas. While these applications have proven successful in retrospective studies, very few of them were…

Artificial Intelligence · Computer Science 2023-08-11 Nicoletta Prentzas , Antonis Kakas , Constantinos S. Pattichis

The clinical adoption of biomedical vision-language models is hindered by prompt optimization techniques that produce either uninterpretable latent vectors or single textual prompts. This lack of transparency and failure to capture the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Kaushitha Silva , Mansitha Eashwara , Sanduni Ubayasiri , Ruwan Tennakoon , Damayanthi Herath

Human understandable explanation of deep learning models is essential for various critical and sensitive applications. Unlike image or tabular data where the importance of each input feature (for the classifier's decision) can be directly…

Machine Learning · Computer Science 2025-04-07 Shahbaz Rezaei , Xin Liu

Chest X-ray (CXR) interpretation is a fundamental yet complex clinical task that increasingly relies on artificial intelligence for automation. However, traditional monolithic models often lack the nuanced reasoning required for trustworthy…

Computer Vision and Pattern Recognition · Computer Science 2026-04-06 Shawn Young , Lijian Xu

Medical image analysis often faces significant challenges due to limited expert-annotated data, hindering both model generalization and clinical adoption. We propose an expert-guided explainable few-shot learning framework that integrates…

Image and Video Processing · Electrical Eng. & Systems 2025-09-12 Ifrat Ikhtear Uddin , Longwei Wang , KC Santosh

Diagnosis based on medical images, such as X-ray images, often involves manual annotation of anatomical keypoints. However, this process involves significant human efforts and can thus be a bottleneck in the diagnostic process. To fully…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Jinhee Kim , Taesung Kim , Taewoo Kim , Jaegul Choo , Dong-Wook Kim , Byungduk Ahn , In-Seok Song , Yoon-Ji Kim

Despite the success of deep neural networks in chest X-ray (CXR) diagnosis, supervised learning only allows the prediction of disease classes that were seen during training. At inference, these networks cannot predict an unseen disease…

Computer Vision and Pattern Recognition · Computer Science 2021-07-15 Nasir Hayat , Hazem Lashen , Farah E. Shamout

Deep learning (DL) has revolutionized the field of document image analysis, showcasing superhuman performance across a diverse set of tasks. However, the inherent black-box nature of deep learning models still presents a significant…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Saifullah Saifullah , Stefan Agne , Andreas Dengel , Sheraz Ahmed

Medical image classification is a critical problem for healthcare, with the potential to alleviate the workload of doctors and facilitate diagnoses of patients. However, two challenges arise when deploying deep learning models to real-world…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 An Yan , Yu Wang , Yiwu Zhong , Zexue He , Petros Karypis , Zihan Wang , Chengyu Dong , Amilcare Gentili , Chun-Nan Hsu , Jingbo Shang , Julian McAuley

Recent research has supported that system explainability improves user trust and willingness to use medical AI for diagnostic support. In this paper, we use chest disease diagnosis based on X-Ray images as a case study to investigate user…

Human-Computer Interaction · Computer Science 2022-04-27 Yao Rong , Nora Castner , Efe Bozkir , Enkelejda Kasneci

Medical automatic diagnosis aims to imitate human doctors in real-world diagnostic processes and to achieve accurate diagnoses by interacting with the patients. The task is formulated as a sequential decision-making problem with a series of…

Machine Learning · Computer Science 2022-06-07 Hongyi Yuan , Sheng Yu

Explaining decisions of black-box classifiers is paramount in sensitive domains such as medical imaging since clinicians confidence is necessary for adoption. Various explanation approaches have been proposed, among which perturbation based…

Computer Vision and Pattern Recognition · Computer Science 2020-12-15 Martin Charachon , Céline Hudelot , Paul-Henry Cournède , Camille Ruppli , Roberto Ardon

Would you trust physicians if they cannot explain their decisions to you? Medical diagnostics using machine learning gained enormously in importance within the last decade. However, without further enhancements many state-of-the-art machine…

Machine Learning · Computer Science 2022-06-01 Emanuel Slany , Yannik Ott , Stephan Scheele , Jan Paulus , Ute Schmid

Deep neural networks excel in radiological image classification but frequently suffer from poor interpretability, limiting clinical acceptance. We present MedicalPatchNet, an inherently self-explainable architecture for chest X-ray…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Patrick Wienholt , Christiane Kuhl , Jakob Nikolas Kather , Sven Nebelung , Daniel Truhn

Self-supervised contrastive learning between pairs of multiple views of the same image has been shown to successfully leverage unlabeled data to produce meaningful visual representations for both natural and medical images. However, there…

Image and Video Processing · Electrical Eng. & Systems 2021-10-19 Yen Nhi Truong Vu , Richard Wang , Niranjan Balachandar , Can Liu , Andrew Y. Ng , Pranav Rajpurkar

This challenge tackles multi-label classification for known chest X-ray (CXR) lesions and zero-shot classification for unseen ones. To handle diverse CXR projections, we integrate projection-specific models via a classification network into…

Computer Vision and Pattern Recognition · Computer Science 2026-04-03 Juno Cho , Dohui Kim , Mingeon Kim , Hyunseo Jang , Chang Sun Lee , Jong Chul Ye

Explainable AI (XAI) can greatly enhance user trust and satisfaction in AI-assisted decision-making processes. Recent findings suggest that a single explainer may not meet the diverse needs of multiple users in an AI system; indeed, even…