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Related papers: OCELOT: Overlapped Cell on Tissue Dataset for Hist…

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The histological assessment of human tissue has emerged as the key challenge for detection and treatment of cancer. A plethora of different data sources ranging from tissue microarray data to gene expression, proteomics or metabolomics data…

Computer Vision and Pattern Recognition · Computer Science 2016-01-05 Thomas J. Fuchs , Joachim M. Buhmann

Accurately modeling multi-class cell topology is crucial in digital pathology, as it provides critical insights into tissue structure and pathology. The synthetic generation of cell topology enables realistic simulations of complex tissue…

Image and Video Processing · Electrical Eng. & Systems 2025-03-26 Meilong Xu , Saumya Gupta , Xiaoling Hu , Chen Li , Shahira Abousamra , Dimitris Samaras , Prateek Prasanna , Chao Chen

Lesion detection is an important problem within medical imaging analysis. Most previous work focuses on detecting and segmenting a specialized category of lesions (e.g., lung nodules). However, in clinical practice, radiologists are…

Computer Vision and Pattern Recognition · Computer Science 2020-05-29 Ke Yan , Jinzheng Cai , Adam P. Harrison , Dakai Jin , Jing Xiao , Le Lu

Cell detection in histopathology images is of great interest to clinical practice and research, and convolutional neural networks (CNNs) have achieved remarkable cell detection results. Typically, to train CNN-based cell detection models,…

Computer Vision and Pattern Recognition · Computer Science 2023-02-17 Zipei Zhao , Fengqian Pang , Yaou Liu , Zhiwen Liu , Chuyang Ye

Accurate cell instance segmentation is foundational for digital pathology analysis. Existing methods based on contour detection and distance mapping still face significant challenges in processing complex and dense cellular regions. Graph…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Rui Sun , Yiwen Yang , Kaiyu Guo , Chen Jiang , Dongli Xu , Zhaonan Liu , Tan Pan , Limei Han , Xue Jiang , Wu Wei , Yuan Cheng

Many fields, such as neuroscience, are experiencing the vast proliferation of cellular data, underscoring the need for organizing and interpreting large datasets. A popular approach partitions data into manageable subsets via hierarchical…

Quantitative Methods · Quantitative Biology 2024-03-07 Diek W. Wheeler , Giorgio A. Ascoli

In radiologists' routine work, one major task is to read a medical image, e.g., a CT scan, find significant lesions, and describe them in the radiology report. In this paper, we study the lesion description or annotation problem. Given a…

Computer Vision and Pattern Recognition · Computer Science 2019-04-30 Ke Yan , Yifan Peng , Veit Sandfort , Mohammadhadi Bagheri , Zhiyong Lu , Ronald M. Summers

Cells are the fundamental unit of biological organization, and identifying them in imaging data - cell segmentation - is a critical task for various cellular imaging experiments. While deep learning methods have led to substantial progress…

Whole-slide image (WSI) preprocessing, comprising tissue detection followed by patch extraction, is foundational to AI-driven computational pathology but remains a major bottleneck for scaling to large and heterogeneous cohorts. We present…

Motivation: Understanding functions of proteins in specific human tissues is essential for insights into disease diagnostics and therapeutics, yet prediction of tissue-specific cellular function remains a critical challenge for biomedicine.…

Machine Learning · Computer Science 2017-07-18 Marinka Zitnik , Jure Leskovec

Histopathology remains the gold standard for diagnosis of various cancers. Recent advances in computer vision, specifically deep learning, have facilitated the analysis of histopathology images for various tasks, including immune cell…

Quantitative Methods · Quantitative Biology 2023-11-02 Jakub R. Kaczmarzyk , Tahsin M. Kurc , Shahira Abousamra , Rajarsi Gupta , Joel H. Saltz , Peter K. Koo

Identifying cell types and subtypes in routine histopathology is fundamental for understanding disease. Existing tile-based models capture nuclear detail but miss the broader tissue context that influences cell identity. Current human…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Yinuo Xu , Yan Cui , Mingyao Li , Zhi Huang

Pathology deals with the practice of discovering the reasons for disease by analyzing the body samples. The most used way in this field, is to use histology which is basically studying and viewing microscopic structures of cell and tissues.…

Image and Video Processing · Electrical Eng. & Systems 2021-11-08 Virender Ranga , Shivam Gupta , Priyansh Agrawal , Jyoti Meena

Automatically identifying the structural substrates underlying cardiac abnormalities can potentially provide real-time guidance for interventional procedures. With the knowledge of cardiac tissue substrates, the treatment of complex…

Image and Video Processing · Electrical Eng. & Systems 2022-06-10 Ziyi Huang , Yu Gan , Theresa Lye , Yanchen Liu , Haofeng Zhang , Andrew Laine , Elsa Angelini , Christine Hendon

Bone marrow cytology is required to make a hematological diagnosis, influencing critical clinical decision points in hematology. However, bone marrow cytology is tedious, limited to experienced reference centers and associated with high…

Image and Video Processing · Electrical Eng. & Systems 2021-07-09 Rohollah Moosavi Tayebi , Youqing Mu , Taher Dehkharghanian , Catherine Ross , Monalisa Sur , Ronan Foley , Hamid R. Tizhoosh , Clinton JV Campbell

Improving the retrieval relevance on noisy datasets is an emerging need for the curation of a large-scale clean dataset in the medical domain. While existing methods can be applied for class-wise retrieval (aka. inter-class), they cannot…

Computer Vision and Pattern Recognition · Computer Science 2022-04-08 Xiaoyuan Guo , Jiali Duan , Saptarshi Purkayastha , Hari Trivedi , Judy Wawira Gichoya , Imon Banerjee

Histopathology refers to the examination by a pathologist of biopsy samples. Histopathology images are captured by a microscope to locate, examine, and classify many diseases, such as different cancer types. They provide a detailed view of…

Image and Video Processing · Electrical Eng. & Systems 2020-11-12 Naira Elazab , Hassan Soliman , Shaker El-Sappagh , S. M. Riazul Islam , Mohammed Elmogy

Table structure recognition is a key task in document analysis. However, the geometric deformation in deformed tables causes a weak correlation between content information and structure, resulting in downstream tasks not being able to…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Long Liu , Cihui Yang

Cancer diseases constitute one of the most significant societal challenges. In this paper, we introduce a novel histopathological dataset for prostate cancer detection. The proposed dataset, consisting of over 2.6 million tissue patches…

Early diagnosis of the cancer cells is necessary for making an effective treatment plan and for the health and safety of a patient. Nowadays, doctors usually use a histological grade that pathologists determine by performing a…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Varan Singh Rohila , Neeraj Lalwani , Lochan Basyal