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Large language models (LLMs) demonstrate remarkable medical expertise, but data privacy concerns impede their direct use in healthcare environments. Although offering improved data privacy protection, domain-specific small language models…

Computation and Language · Computer Science 2024-05-17 Xinlu Zhang , Shiyang Li , Xianjun Yang , Chenxin Tian , Yao Qin , Linda Ruth Petzold

The rapid development of large language models (LLMs) has transformed many industries, including healthcare. However, previous medical LLMs have largely focused on leveraging general medical knowledge to provide responses, without…

Computation and Language · Computer Science 2024-12-23 Ruize Shi , Hong Huang , Wei Zhou , Kehan Yin , Kai Zhao , Yun Zhao

In-hospital mortality (IHM) prediction for ICU patients is critical for timely interventions and efficient resource allocation. While structured physiological data provides quantitative insights, clinical notes offer unstructured,…

Computation and Language · Computer Science 2024-11-27 Harshavardhan Battula , Jiacheng Liu , Jaideep Srivastava

Large language models (LLMs) have become increasingly popular in medical domains to assist physicians with a variety of clinical and operational tasks. Given the fast-paced and high-stakes environment of emergency departments (EDs), small…

Computation and Language · Computer Science 2025-10-07 Zirui Wang , Jiajun Wu , Braden Teitge , Jessalyn Holodinsky , Steve Drew

Large language models (LLMs) can generate or synthesize clinical text for a wide range of applications, from improving clinical documentation to augmenting clinical text analytics. Yet evaluations typically focus on a narrow aspect -- such…

Computation and Language · Computer Science 2026-05-19 Jinghui Liu , Sarvesh Soni , Anthony Nguyen

Large language models (LLMs) hold great promise in summarizing medical evidence. Most recent studies focus on the application of proprietary LLMs. Using proprietary LLMs introduces multiple risk factors, including a lack of transparency and…

Large language models (LLMs) have shown promise in safety-critical applications such as healthcare, yet the ability to quantify performance has lagged. An example of this challenge is in evaluating a summary of the patient's medical record.…

Computation and Language · Computer Science 2024-11-13 Elliot Schumacher , Daniel Rosenthal , Dhruv Naik , Varun Nair , Luladay Price , Geoffrey Tso , Anitha Kannan

In the past decade a surge in the amount of electronic health record (EHR) data in the United States, attributed to a favorable policy environment created by the Health Information Technology for Economic and Clinical Health (HITECH) Act of…

Computation and Language · Computer Science 2025-12-08 Ivan Makohon , Mohamad Najafi , Jian Wu , Mathias Brochhausen , Yaohang Li

Large Language Models (LLM) are a new class of computation engines, "programmed" via prompt engineering. We are still learning how to best "program" these LLMs to help developers. We start with the intuition that developers tend to…

Software Engineering · Computer Science 2024-01-15 Toufique Ahmed , Kunal Suresh Pai , Premkumar Devanbu , Earl T. Barr

Large language models (LLMs) are increasingly used to generate summaries from clinical notes. However, their ability to preserve essential diagnostic information remains underexplored, which could lead to serious risks for patient care.…

Computation and Language · Computer Science 2026-02-20 Heloisa Oss Boll , Antonio Oss Boll , Leticia Puttlitz Boll , Ameen Abu Hanna , Iacer Calixto

Large language models (LLMs) are increasingly used to extract structured information from free-text clinical records, but prior work often focuses on single tasks, limited models, and English-language reports. We evaluated 15 open-weight…

Effective clinical history taking is a foundational yet underexplored component of clinical reasoning. While large language models (LLMs) have shown promise on static benchmarks, they often fall short in dynamic, multi-turn diagnostic…

Computation and Language · Computer Science 2026-01-30 Yang Zhou , Zhenting Sheng , Mingrui Tan , Yuting Song , Jun Zhou , Yu Heng Kwan , Lian Leng Low , Yang Bai , Yong Liu

The problem of data sparsity has long been a challenge in recommendation systems, and previous studies have attempted to address this issue by incorporating side information. However, this approach often introduces side effects such as…

Information Retrieval · Computer Science 2024-01-09 Wei Wei , Xubin Ren , Jiabin Tang , Qinyong Wang , Lixin Su , Suqi Cheng , Junfeng Wang , Dawei Yin , Chao Huang

Understanding a medical conversation between a patient and a physician poses a unique natural language understanding challenge since it combines elements of standard open ended conversation with very domain specific elements that require…

Computation and Language · Computer Science 2020-09-21 Anirudh Joshi , Namit Katariya , Xavier Amatriain , Anitha Kannan

As real-world datasets become more complex and heterogeneous, supervised learning is often bottlenecked by input representation design. Modeling multimodal data, such as time-series, free text, and structured records, often requires…

Artificial Intelligence · Computer Science 2026-05-22 Ilker Demirel , Lawrence Shi , Zeshan Hussain , David Sontag

Deep-learning-based clinical decision support using structured electronic health records (EHR) has been an active research area for predicting risks of mortality and diseases. Meanwhile, large amounts of narrative clinical notes provide…

Computation and Language · Computer Science 2023-05-10 Weimin Lyu , Xinyu Dong , Rachel Wong , Songzhu Zheng , Kayley Abell-Hart , Fusheng Wang , Chao Chen

Summarization models often generate text that is poorly calibrated to quality metrics because they are trained to maximize the likelihood of a single reference (MLE). To address this, recent work has added a calibration step, which exposes…

Unstructured clinical text in EHRs contains crucial information for applications including decision support, trial matching, and retrospective research. Recent work has applied BERT-based models to clinical information extraction and text…

Computation and Language · Computer Science 2020-11-13 Kexin Huang , Sankeerth Garapati , Alexander S. Rich

Large language models (LLMs) have revolutionized NLP research. Notably, in-context learning enables their use as evaluation metrics for natural language generation, making them particularly advantageous in low-resource scenarios and…

Computation and Language · Computer Science 2024-11-19 Christoph Leiter , Steffen Eger

Researchers are increasingly using language models (LMs) for text annotation. These approaches rely only on a prompt telling the model to return a given output according to a set of instructions. The reproducibility of LM outputs may…

Computation and Language · Computer Science 2026-05-18 Christopher Barrie , Elli Palaiologou , Petter Törnberg
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