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Rich data and powerful machine learning models allow us to design drugs for a specific protein target \textit{in silico}. Recently, the inclusion of 3D structures during targeted drug design shows superior performance to other target-free…

Biomolecules · Quantitative Biology 2023-03-08 Jiaqi Guan , Wesley Wei Qian , Xingang Peng , Yufeng Su , Jian Peng , Jianzhu Ma

Generative models have shown strong generation ability while efficient likelihood estimation is less explored. Energy-based models~(EBMs) define a flexible energy function to parameterize unnormalized densities efficiently but are notorious…

Machine Learning · Computer Science 2024-06-11 Cong Geng , Tian Han , Peng-Tao Jiang , Hao Zhang , Jinwei Chen , Søren Hauberg , Bo Li

We aim to evaluate Large Language Models (LLMs) for embodied decision making. While a significant body of work has been leveraging LLMs for decision making in embodied environments, we still lack a systematic understanding of their…

Diffusion models have been successfully applied to robotics problems such as manipulation and vehicle path planning. In this work, we explore their application to end-to-end navigation -- including both perception and planning -- by…

Robotics · Computer Science 2024-09-27 L. Lao Beyer , S. Karaman

Diffusion models have shown promising capabilities in trajectory generation for planning in offline reinforcement learning (RL). However, conventional diffusion-based planning methods often fail to account for the fact that generating…

Artificial Intelligence · Computer Science 2026-02-25 Hanping Zhang , Yuhong Guo

While many unsupervised learning models focus on one family of tasks, either generative or discriminative, we explore the possibility of a unified representation learner: a model which uses a single pre-training stage to address both…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Soumik Mukhopadhyay , Matthew Gwilliam , Vatsal Agarwal , Namitha Padmanabhan , Archana Swaminathan , Srinidhi Hegde , Tianyi Zhou , Abhinav Shrivastava

Convolutional networks are successful, but they have recently been outperformed by new neural networks that are equivariant under rotations and translations. These new networks work better because they do not struggle with learning each…

Computer Vision and Pattern Recognition · Computer Science 2021-02-16 Philip Müller , Vladimir Golkov , Valentina Tomassini , Daniel Cremers

Implicit policies parameterized by generative models, such as Diffusion Policy, have become the standard for policy learning and Vision-Language-Action (VLA) models in robotics. However, these approaches often suffer from high computational…

Robotics · Computer Science 2025-11-03 Travis Davies , Yiqi Huang , Alexi Gladstone , Yunxin Liu , Xiang Chen , Heng Ji , Huxian Liu , Luhui Hu

Recent methods for molecular generation face a trade-off: they either enforce strict equivariance with costly architectures or relax it to gain scalability and flexibility. We propose a frame-based diffusion paradigm that achieves…

Machine Learning · Computer Science 2025-10-07 Mohan Guo , Cong Liu , Patrick Forré

Contrastive Reinforcement Learning (CRL) provides a promising framework for extracting useful structured representations from unlabeled interactions. By pulling together state-action pairs and their corresponding future states, while…

Robotics · Computer Science 2025-07-23 Arsh Tangri , Nichols Crawford Taylor , Haojie Huang , Robert Platt

Diffusion-based generative models (DBGMs) perturb data to a target noise distribution and reverse this process to generate samples. The choice of noising process, or inference diffusion process, affects both likelihoods and sample quality.…

Machine Learning · Computer Science 2023-03-06 Raghav Singhal , Mark Goldstein , Rajesh Ranganath

In recent years, Large Language Models (LLMs) have demonstrated remarkable capabilities in understanding and solving mathematical problems, leading to advancements in various fields. We propose an LLM-embodied path planning framework for…

Robotics · Computer Science 2024-07-08 Xiangrui Kong , Wenxiao Zhang , Jin Hong , Thomas Braunl

We introduce Efficient Motion Diffusion Model (EMDM) for fast and high-quality human motion generation. Current state-of-the-art generative diffusion models have produced impressive results but struggle to achieve fast generation without…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Wenyang Zhou , Zhiyang Dou , Zeyu Cao , Zhouyingcheng Liao , Jingbo Wang , Wenjia Wang , Yuan Liu , Taku Komura , Wenping Wang , Lingjie Liu

Embodied agents have shown promising generalization capabilities across diverse physical environments, making them essential for a wide range of real-world applications. However, building versatile embodied agents poses critical challenges…

Robotics · Computer Science 2025-08-12 Shengli Zhou , Xiangchen Wang , Jinrui Zhang , Ruozai Tian , Rongtao Xu , Feng Zheng

Accurately modeling agent behaviors is an important task in self-driving. It is also a task with many symmetries, such as equivariance to the order of agents and objects in the scene or equivariance to arbitrary roto-translations of the…

Robotics · Computer Science 2026-04-03 Scott Xu , Dian Chen , Kelvin Wong , Chris Zhang , Kion Fallah , Raquel Urtasun

Urban environments, characterized by their complex, multi-layered networks encompassing physical, social, economic, and environmental dimensions, face significant challenges in the face of rapid urbanization. These challenges, ranging from…

Artificial Intelligence · Computer Science 2023-12-20 Fengli Xu , Jun Zhang , Chen Gao , Jie Feng , Yong Li

Classical paradigms for distributed learning, such as federated or decentralized gradient descent, employ consensus mechanisms to enforce homogeneity among agents. While these strategies have proven effective in i.i.d. scenarios, they can…

Machine Learning · Computer Science 2023-04-18 Shreya Wadehra , Roula Nassif , Stefan Vlaski

Recent advances in embodied AI highlight the potential of vision language models (VLMs) as agents capable of perception, reasoning, and interaction in complex environments. However, top-performing systems rely on large-scale models that are…

Learning for robot navigation presents a critical and challenging task. The scarcity and costliness of real-world datasets necessitate efficient learning approaches. In this letter, we exploit Euclidean symmetry in planning for 2D…

Robotics · Computer Science 2024-01-30 Linfeng Zhao , Hongyu Li , Taskin Padir , Huaizu Jiang , Lawson L. S. Wong

Acting in human environments is a crucial capability for general-purpose robots, necessitating a robust understanding of natural language and its application to physical tasks. This paper seeks to harness the capabilities of diffusion…

Robotics · Computer Science 2026-04-28 Jonas Bode , Raphael Memmesheimer , Sven Behnke
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