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Recently, diffusion probabilistic models (DPMs) have achieved promising results in diverse generative tasks. A typical DPM framework includes a forward process that gradually diffuses the data distribution and a reverse process that…

Machine Learning · Computer Science 2023-10-31 Tianyu Pang , Cheng Lu , Chao Du , Min Lin , Shuicheng Yan , Zhijie Deng

In the medical domain, acquiring large datasets is challenging due to both accessibility issues and stringent privacy regulations. Consequently, data availability and privacy protection are major obstacles to applying machine learning in…

Image and Video Processing · Electrical Eng. & Systems 2025-07-02 Wenwu Tang , Khaled Seyam , Bin Yang

Recent advances in generative models for medical imaging have shown promise in representing multiple modalities. However, the variability in modality availability across datasets limits the general applicability of the synthetic data they…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Sven Lüpke , Yousef Yeganeh , Ehsan Adeli , Nassir Navab , Azade Farshad

Despite the proliferation of generative models, achieving fast sampling during inference without compromising sample diversity and quality remains challenging. Existing models such as Denoising Diffusion Probabilistic Models (DDPM) deliver…

Machine Learning · Computer Science 2023-10-12 Yanwu Xu , Mingming Gong , Shaoan Xie , Wei Wei , Matthias Grundmann , Kayhan Batmanghelich , Tingbo Hou

Early and accurate detection of Alzheimer's disease (AD) is crucial for enabling timely intervention and improving outcomes. However, developing reliable machine learning (ML) models for AD diagnosis is challenging due to limited labeled…

Machine Learning · Computer Science 2025-11-27 Abolfazl Moslemi , Hossein Peyvandi

The diffusion model has recently emerged as a potent approach in computer vision, demonstrating remarkable performances in the field of generative artificial intelligence. Capable of producing high-quality synthetic images, diffusion models…

Image and Video Processing · Electrical Eng. & Systems 2025-05-14 Abdullah , Tao Huang , Ickjai Lee , Euijoon Ahn

Electronic health records (EHRs) include simple features like patient age together with more complex data like care history that are informative but not easily represented as individual features. To better harness such data, we developed an…

Artificial Intelligence · Computer Science 2023-02-14 Jacqueline K. Kueper , Jennifer Rayner , Daniel J. Lizotte

In this work, we address the challenge of multi-task image generation with limited data for denoising diffusion probabilistic models (DDPM), a class of generative models that produce high-quality images by reversing a noisy diffusion…

Machine Learning · Computer Science 2023-11-29 Delaram Pirhayatifard , Mohammad Taha Toghani , Guha Balakrishnan , César A. Uribe

Electronic Health Records (EHRs) are pivotal in clinical practices, yet their retrieval remains a challenge mainly due to semantic gap issues. Recent advancements in dense retrieval offer promising solutions but existing models, both…

Information Retrieval · Computer Science 2025-07-25 Zhengyun Zhao , Huaiyuan Ying , Yue Zhong , Sheng Yu

Healthcare research and development face significant obstacles due to data scarcity and stringent privacy regulations, such as HIPAA and the GDPR, restricting access to essential real-world medical data. These limitations impede innovation,…

Machine Learning · Computer Science 2025-10-17 Md Ibrahim Shikder Mahin , Md Shamsul Arefin , Md Tanvir Hasan

Recent research in tabular data synthesis has focused on single tables, whereas real-world applications often involve complex data with tens or hundreds of interconnected tables. Previous approaches to synthesizing multi-relational…

Artificial Intelligence · Computer Science 2024-11-15 Wei Pang , Masoumeh Shafieinejad , Lucy Liu , Stephanie Hazlewood , Xi He

Epidemiologic studies of infectious diseases often rely on models of contact networks to capture the complex interactions that govern disease spread, and ongoing projects aim to vastly increase the scale at which such data can be collected.…

Cryptography and Security · Computer Science 2026-04-10 Shlomi Hod , Debanuj Nayak , Jason R. Gantenberg , Iden Kalemaj , Thomas A. Trikalinos , Adam Smith

Generating synthetic data through generative models is gaining interest in the ML community and beyond, promising a future where datasets can be tailored to individual needs. Unfortunately, synthetic data is usually not perfect, resulting…

Machine Learning · Computer Science 2023-07-11 Boris van Breugel , Zhaozhi Qian , Mihaela van der Schaar

As deep learning-based, data-driven information extraction systems become increasingly integrated into modern document processing workflows, one primary concern is the risk of malicious leakage of sensitive private data from these systems.…

Cryptography and Security · Computer Science 2025-08-07 Saifullah Saifullah , Stefan Agne , Andreas Dengel , Sheraz Ahmed

Diffusion Probabilistic Models (DPMs) have emerged as a powerful class of deep generative models, achieving remarkable performance in image synthesis tasks. However, these models face challenges in terms of widespread adoption due to their…

Computer Vision and Pattern Recognition · Computer Science 2024-06-03 Kidist Amde Mekonnen , Nicola Dall'Asen , Paolo Rota

In recent years, large amounts of electronic health records (EHRs) concerning chronic diseases have been collected to facilitate medical diagnosis. Modeling the dynamic properties of EHRs related to chronic diseases can be efficiently done…

Machine Learning · Computer Science 2025-02-18 Di Wang , Yao Wang , Shao-Bo Lin

Recent advancements in large language models (LLMs) have significantly enhanced their knowledge and generative capabilities, leading to a surge of interest in leveraging LLMs for high-quality data synthesis. However, synthetic data…

Machine Learning · Computer Science 2025-06-11 Ying Zhou , Xinyao Wang , Yulei Niu , Yaojie Shen , Lexin Tang , Fan Chen , Ben He , Le Sun , Longyin Wen

We propose a novel pipeline for the generation of synthetic ultrasound images via Denoising Diffusion Probabilistic Models (DDPMs) guided by cardiac semantic label maps. We show that these synthetic images can serve as a viable substitute…

Image and Video Processing · Electrical Eng. & Systems 2023-08-16 David Stojanovski , Uxio Hermida , Pablo Lamata , Arian Beqiri , Alberto Gomez

Single Domain Generalization (SDG) aims to train models that maintain consistent performance across diverse scenarios using data from a single source. While latent diffusion models (LDMs) show promise for augmenting limited source data, our…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Hao Li , Yubin Xiao , Ke Liang , Mengzhu Wang , Long Lan , Kenli Li , Xinwang Liu

Variable selection for high-dimensional, highly correlated data has long been a challenging problem, often yielding unstable and unreliable models. We propose a resample-aggregate framework that exploits diffusion models' ability to…

Methodology · Statistics 2025-08-20 Minjie Wang , Xiaotong Shen , Wei Pan