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Neutral macroevolutionary models, such as the Yule model, give rise to a probability distribution on the set of discrete rooted binary trees over a given leaf set. Such models can provide a signal as to the approximate location of the root…

Populations and Evolution · Quantitative Biology 2012-03-28 Mike Steel

Observability is a modelling property that describes the possibility of inferring the internal state of a system from observations of its output. A related property, structural identifiability, refers to the theoretical possibility of…

Quantitative Methods · Quantitative Biology 2018-12-12 Alejandro F. Villaverde

The reconstruction of a species phylogeny from genomic data faces two significant hurdles: 1) the trees describing the evolution of each individual gene--i.e., the gene trees--may differ from the species phylogeny and 2) the molecular…

Machine Learning · Computer Science 2017-07-17 Gautam Dasarathy , Elchanan Mossel , Robert Nowak , Sebastien Roch

For a uniform random labelled tree, we find the limiting distribution of tree parameters which are stable (in some sense) with respect to local perturbations of the tree structure. The proof is based on the martingale central limit theorem…

Combinatorics · Mathematics 2022-06-16 Mikhail Isaev , Angus Southwell , Maksim Zhukovskii

Dissimilarity measures for (possibly weighted) phylogenetic trees based on the comparison of their vectors of path lengths between pairs of taxa, have been present in the systematics literature since the early seventies. But, as far as…

Populations and Evolution · Quantitative Biology 2008-07-06 Gabriel Cardona , Merce Llabres , Francesc Rossello , Gabriel Valiente

Tree-based protocols are ubiquitous in distributed systems. They are flexible, they perform generally well, and, in static conditions, their analysis is mostly simple. Under churn, however, node joins and failures can have complex global…

Distributed, Parallel, and Cluster Computing · Computer Science 2010-04-27 Supriya Krishnamurthy , John Ardelius , Erik Aurell , Mads Dam , Rolf Stadler , Fetahi Wuhib

Structural information of phylogenetic tree topologies plays an important role in phylogenetic inference. However, finding appropriate topological structures for specific phylogenetic inference tasks often requires significant design effort…

Machine Learning · Statistics 2023-02-20 Cheng Zhang

A rooted phylogenetic network is a directed acyclic graph with a single root, whose sinks correspond to a set of species. As such networks are useful for representing the evolution of species that have undergone reticulate evolution, there…

Populations and Evolution · Quantitative Biology 2022-06-28 Vincent Moulton , Taoyang Wu

Most phylogenetic models assume that the evolutionary process is stationary and reversible. As a result, the root of the tree cannot be inferred as part of the analysis because the likelihood of the data does not depend on the position of…

Populations and Evolution · Quantitative Biology 2017-02-21 S. Cherlin , T. M. W. Nye , S. E. Heaps , R. J. Boys , T. A. Williams , T. M. Embley

We prove identifiability of parameters for a broad class of random graph mixture models. These models are characterized by a partition of the set of graph nodes into latent (unobservable) groups. The connectivities between nodes are…

Statistics Theory · Mathematics 2010-06-07 Elizabeth S. Allman , Catherine Matias , John A. Rhodes

Phylogenetic networks are rooted, labelled directed acyclic graphs which are commonly used to represent reticulate evolution. There is a close relationship between phylogenetic networks and multi-labelled trees (MUL-trees). Indeed, any…

Populations and Evolution · Quantitative Biology 2015-06-16 Katharina T. Huber , Vincent Moulton , Mike Steel , Taoyang Wu

We introduce a class of linear compartmental models called identifiable path/cycle models which have the property that all of the monomial functions of parameters associated to the directed cycles and paths from input compartments to output…

Algebraic Geometry · Mathematics 2021-09-01 Cashous Bortner , Nicolette Meshkat

Construction of phylogenetic trees and networks for extant species from their characters represents one of the key problems in phylogenomics. While solution to this problem is not always uniquely defined and there exist multiple methods for…

Populations and Evolution · Quantitative Biology 2016-08-10 Nikita Alexeev , Max A. Alekseyev

Phylogenetic networks are rooted acyclic directed graphs in which the leaves are identified with members of a set X of species. The cluster of a vertex is the set of leaves that are descendants of the vertex. A network is "distinct-cluster"…

Combinatorics · Mathematics 2017-04-11 Stephen J. Willson

We prove identifiability of the tree parameters of the 3-class Jukes-Cantor mixture model. The proof uses ideas from algebraic statistics, in particular: finding phylogenetic invariants that separate the varieties associated to different…

Populations and Evolution · Quantitative Biology 2014-08-12 Colby Long , Seth Sullivant

An old problem in multivariate statistics is that linear Gaussian models are often unidentifiable, i.e. some parameters cannot be uniquely estimated. In factor (component) analysis, an orthogonal rotation of the factors is unidentifiable,…

Machine Learning · Statistics 2023-05-04 Aapo Hyvärinen , Ilyes Khemakhem , Ricardo Monti

Linear structural causal models (SCMs) are used to express and analyse the relationships between random variables. Direct causal effects are represented as directed edges and confounding factors as bidirected edges. Identifying the causal…

Artificial Intelligence · Computer Science 2024-03-06 Aaryan Gupta , Markus Bläser

Phylogenetic networks are an extension of phylogenetic trees which are used to represent evolutionary histories in which reticulation events (such as recombination and hybridization) have occurred. A central question for such networks is…

Populations and Evolution · Quantitative Biology 2018-03-28 Andrew Francis , Vincent Moulton

In this paper, an original result in terms of a sufficient condition to test identifiability of nonlinear delayed-differential models with constant delays and multi-inputs is given. The identifiability is studied for the linearized system…

Dynamical Systems · Mathematics 2010-09-10 Carine Jauberthie , Louise Travé-Massuyès

We investigate parameterized algorithms for computing the average-tree phylogenetic diversity (APD) in rooted phylogenetic networks, studying the problem under different structural parameters that capture the deviation of a network from a…

Data Structures and Algorithms · Computer Science 2026-05-01 Leo van Iersel , Mark Jones , Jannik Schestag , Celine Scornavacca , Mathias Weller