English
Related papers

Related papers: CCPL: Cross-modal Contrastive Protein Learning

200 papers

This work aims to adapt large-scale pre-trained vision-language models, such as contrastive language-image pretraining (CLIP), to enhance the performance of object reidentification (Re-ID) across various supervision settings. Although…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Jiachen Li , Xiaojin Gong

Large-scale cross-lingual pre-trained language models (xPLMs) have shown effectiveness in cross-lingual sequence labeling tasks (xSL), such as cross-lingual machine reading comprehension (xMRC) by transferring knowledge from a high-resource…

Computation and Language · Computer Science 2022-04-12 Nuo Chen , Linjun Shou , Ming Gong , Jian Pei , Daxin Jiang

In recent years, self-supervised representation learning for skeleton-based action recognition has been developed with the advance of contrastive learning methods. The existing contrastive learning methods use normal augmentations to…

Computer Vision and Pattern Recognition · Computer Science 2021-12-08 Tianyu Guo , Hong Liu , Zhan Chen , Mengyuan Liu , Tao Wang , Runwei Ding

Continual learning (CL) aims to train models sequentially over multiple domains without forgetting previously learned knowledge. However, existing CL methods optimize for in-domain performance and are therefore prone to learning spurious,…

Machine Learning · Computer Science 2026-05-18 Pascal Janetzky , Tobias Schlagenhauf , Stefan Feuerriegel

Determining the different conformational states of a protein and the transition paths between them is key to fully understanding the relationship between biomolecular structure and function. This can be accomplished by sampling protein…

Biological Physics · Physics 2021-03-24 Venkata K. Ramaswamy , Chris G. Willcocks , Matteo T. Degiacomi

Pre-training has proven to be effective in unsupervised machine translation due to its ability to model deep context information in cross-lingual scenarios. However, the cross-lingual information obtained from shared BPE spaces is…

Computation and Language · Computer Science 2019-09-04 Shuo Ren , Yu Wu , Shujie Liu , Ming Zhou , Shuai Ma

Cross-lingual adaptation, a special case of domain adaptation, refers to the transfer of classification knowledge between two languages. In this article we describe an extension of Structural Correspondence Learning (SCL), a recently…

Information Retrieval · Computer Science 2010-08-26 Peter Prettenhofer , Benno Stein

Part feature learning is critical for fine-grained semantic understanding in vehicle re-identification. However, existing approaches directly model part features and global features, which can easily lead to serious gradient vanishing…

Computer Vision and Pattern Recognition · Computer Science 2023-03-17 Fei Shen , Xiaoyu Du , Liyan Zhang , Xiangbo Shu , Jinhui Tang

Fine-tuning a pre-trained language model via the contrastive learning framework with a large amount of unlabeled sentences or labeled sentence pairs is a common way to obtain high-quality sentence representations. Although the contrastive…

Computation and Language · Computer Science 2022-11-01 Tianduo Wang , Wei Lu

To effectively perform the task of next-word prediction, long short-term memory networks (LSTMs) must keep track of many types of information. Some information is directly related to the next word's identity, but some is more secondary…

Computation and Language · Computer Science 2021-06-01 Qingfeng Lan , Luke Kumar , Martha White , Alona Fyshe

Contrastive Language-Image Pretraining (CLIP) stands out as a prominent method for image representation learning. Various neural architectures, spanning Transformer-based models like Vision Transformers (ViTs) to Convolutional Networks…

Computer Vision and Pattern Recognition · Computer Science 2023-12-25 Cristian Rodriguez-Opazo , Edison Marrese-Taylor , Ehsan Abbasnejad , Hamed Damirchi , Ignacio M. Jara , Felipe Bravo-Marquez , Anton van den Hengel

The dichotomy between the challenging nature of obtaining annotations for activities, and the more straightforward nature of data collection from wearables, has resulted in significant interest in the development of techniques that utilize…

Machine Learning · Computer Science 2022-11-14 Harish Haresamudram , Irfan Essa , Thomas Ploetz

Accurately measuring protein-RNA binding affinity is crucial in many biological processes and drug design. Previous computational methods for protein-RNA binding affinity prediction rely on either sequence or structure features, unable to…

Biomolecules · Quantitative Biology 2025-01-06 Rong Han , Xiaohong Liu , Tong Pan , Jing Xu , Xiaoyu Wang , Wuyang Lan , Zhenyu Li , Zixuan Wang , Jiangning Song , Guangyu Wang , Ting Chen

Pretext Invariant Representation Learning (PIRL) followed by Supervised Fine-Tuning (SFT) has become a standard paradigm for learning with limited labels. We extend this approach to the Positive Unlabeled (PU) setting, where only a small…

Machine Learning · Computer Science 2025-04-11 Anish Acharya , Li Jing , Bhargav Bhushanam , Dhruv Choudhary , Michael Rabbat , Sujay Sanghavi , Inderjit S Dhillon

Motivation: Drug discovery demands rapid quantification of compound-protein interaction (CPI). However, there is a lack of methods that can predict compound-protein affinity from sequences alone with high applicability, accuracy, and…

Biomolecules · Quantitative Biology 2020-12-17 Mostafa Karimi , Di Wu , Zhangyang Wang , Yang Shen

Contrastive self-supervised learning has become a prominent technique in representation learning. The main step in these methods is to contrast semantically similar and dissimilar pairs of samples. However, in the domain of Natural Language…

Computation and Language · Computer Science 2022-06-07 Amrita Bhattacharjee , Mansooreh Karami , Huan Liu

The objective of this paper is to learn semantic representations for sleep stage classification from raw physiological time series. Although supervised methods have gained remarkable performance, they are limited in clinical situations due…

Signal Processing · Electrical Eng. & Systems 2021-10-20 Hongjun Zhang , Jing Wang , Qinfeng Xiao , Jiaoxue Deng , Youfang Lin

Contrastive learning has achieved great success in self-supervised visual representation learning, but existing approaches mostly ignored spatial information which is often crucial for visual representation. This paper presents…

Computer Vision and Pattern Recognition · Computer Science 2020-11-20 Xinyue Huo , Lingxi Xie , Longhui Wei , Xiaopeng Zhang , Hao Li , Zijie Yang , Wengang Zhou , Houqiang Li , Qi Tian

Contrastive self-supervised learning (CSL) is an approach to learn useful representations by solving a pretext task that selects and compares anchor, negative and positive (APN) features from an unlabeled dataset. We present a conceptual…

Computer Vision and Pattern Recognition · Computer Science 2020-09-02 William Falcon , Kyunghyun Cho

The prediction of protein structures from sequences is an important task for function prediction, drug design, and related biological processes understanding. Recent advances have proved the power of language models (LMs) in processing the…

Quantitative Methods · Quantitative Biology 2022-12-01 Bozhen Hu , Jun Xia , Jiangbin Zheng , Cheng Tan , Yufei Huang , Yongjie Xu , Stan Z. Li