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Organisms are equipped with regulatory systems that display a variety of dynamical behaviours ranging from simple stable steady states, to switching and multistability, to oscillations. Earlier work has shown that oscillations in protein…

Molecular Networks · Quantitative Biology 2009-11-13 Simone Pigolotti , Sandeep Krishna , Mogens H. Jensen

Circadian clocks are the central timekeepers of life, allowing cells to anticipate changes between day and night. Experiments in recent years have revealed that circadian clocks can be highly stable, raising the question how reliably they…

Molecular Networks · Quantitative Biology 2016-06-22 Michele Monti , Pieter Rein ten Wolde

Quasi steady state assumptions are often used to simplify complex systems of ordinary differential equations in modelling of biochemical processes. The simplified system is designed to have the same qualitative properties as the original…

Dynamical Systems · Mathematics 2013-12-11 Tomáš Vejchodský

A system formed by a crowded environment of catalytic obstacles and complex oscillatory chemical reactions is inquired. The obstacles are static spheres of equal radius, which are placed in a random way. The chemical reactions are carried…

Chemical Physics · Physics 2018-12-05 Carlos Echeverria , José L. Herrera , Kay Tucci , Orlando Alvarez-Llamoza , Miguel Morales

Long and stable timescales are often observed in complex biochemical networks, such as in emergent oscillations. How these robust dynamics persist remains unclear, given the many stochastic reactions and shorter time scales demonstrated by…

Biological Physics · Physics 2024-08-02 Chongbin Zheng , Evelyn Tang

Subdiffusion has been proposed as an explanation of various kinetic phenomena inside living cells. In order to fascilitate large-scale computational studies of subdiffusive chemical processes, we extend a recently suggested mesoscopic model…

Analysis of PDEs · Mathematics 2018-02-19 Emilie Blanc , Stefan Engblom , Andreas Hellander , Per Lötstedt

A variety of nonlinear models of biological systems generate complex chaotic behaviors that contrast with biological homeostasis, the observation that many biological systems prove remarkably robust in the face of changing external or…

Chaotic Dynamics · Physics 2023-07-07 Jonathan Jaquette , Sonal Kedia , Evelyn Sander , Jonathan D. Touboul

Oscillatory chemical reactions are functional components in a variety of biological contexts. In chemistry, the construction and identification of even rudimentary oscillators remain elusive and lack a general framework. Using…

Molecular Networks · Quantitative Biology 2025-10-10 Alexander Blokhuis , Peter F. Stadler , Nicola Vassena

We study a system of dynamical units, each of which shows excitable or oscillatory behavior, depending on the choice of parameters. When we couple these units with repressive bonds, we can control the duration of collective oscillations for…

Molecular Networks · Quantitative Biology 2014-02-06 Darka Labavic , Hildegard Meyer-Ortmanns

Dissipation is commonly regarded as an obstacle to quantum control, as it induces decoherence and irreversibility. Here we demonstrate that dissipation can instead be exploited as a resource to reshape the dynamics of interacting quantum…

Quantum Physics · Physics 2026-02-20 Debabrata Mondal , Lea F. Santos , S. Sinha

A wide range of organisms features molecular machines, circadian clocks, which generate endogenous oscillations with ~24 h periodicity and thereby synchronize biological processes to diurnal environmental fluctuations. Recently, it has…

Molecular Networks · Quantitative Biology 2016-02-03 Mathias Foo , David E. Somers , Pan-Jun Kim

Boundary-induced pattern formation from a spatially uniform state is investigated using one-dimensional reaction-diffusion equations. The temporal oscillation is successively transformed into a spatially periodic pattern, triggered by…

Pattern Formation and Solitons · Physics 2017-02-01 Takahiro Kohsokabe , Kunihiko Kaneko

Circadian rhythms are acquired through evolution to increase the chances for survival through synchronizing with the daylight cycle. Reliable synchronization is realized through two trade-off properties: regularity to keep time precisely,…

Biological Physics · Physics 2014-10-02 Yoshihiko Hasegawa , Masanori Arita

Circadian clocks are biochemical oscillators that allow organisms to estimate the time of the day. These oscillators are inherently noisy due to the discrete nature of the reactants and the stochastic character of their interactions. To…

Biological Physics · Physics 2018-03-21 Michele Monti , David K. Lubensky , Pieter Rein ten Wolde

Biomedical signals carry signature rhythms of complex physiological processes that control our daily bodily activity. The properties of these rhythms indicate the nature of interaction dynamics among physiological processes that maintain a…

Machine Learning · Computer Science 2020-12-14 Yassin Khalifa , Danilo Mandic , Ervin Sejdić

A universal mechanism of emergence of synchronized low frequency brain wave field activity is presented as a result of nonlinear coupling with flat frequency neuronal forcing. The mechanism utilizes a unique dispersion properties of…

Biological Physics · Physics 2019-06-25 Vitaly L. Galinsky , Lawrence R. Frank

Biological systems can rely on collective formation of a metachronal wave in an ensemble of oscillators for locomotion and for fluid transport. We consider one-dimensional chains of phase oscillators with nearest neighbor interactions,…

Biological Physics · Physics 2023-03-15 A. C. Quillen

We identify a new type of pattern formation in spatially distributed active systems. We simulate one-dimensional two-component systems with predator-prey local interaction and pursuit-evasion taxis between the components. In a sufficiently…

Pattern Formation and Solitons · Physics 2013-05-29 V. N. Biktashev , M. A. Tsyganov

Turing patterns are a central paradigm for describing spatial patterns in nature. The corresponding theory of reaction-diffusion dynamics combines ideal diffusion with nonlinear reactions, resulting in patterns when species diffuse at…

Biological Physics · Physics 2026-01-28 Cathelijne ter Burg , David Zwicker

The theory of biochemical processes needs simple but realistic models of phenomena underlying microscopic dynamics of proteins. Many experiments performed in the 1980s have demonstrated that within the protein native state, apart from usual…

Condensed Matter · Physics 2007-05-23 Michal Kurzynski