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Clinical machine learning models experience significantly degraded performance in datasets not seen during training, e.g., new hospitals or populations. Recent developments in domain generalization offer a promising solution to this problem…

Machine Learning · Computer Science 2021-04-16 Haoran Zhang , Natalie Dullerud , Laleh Seyyed-Kalantari , Quaid Morris , Shalmali Joshi , Marzyeh Ghassemi

Machine learning models typically suffer from the domain shift problem when trained on a source dataset and evaluated on a target dataset of different distribution. To overcome this problem, domain generalisation (DG) methods aim to…

Computer Vision and Pattern Recognition · Computer Science 2020-03-16 Kaiyang Zhou , Yongxin Yang , Timothy Hospedales , Tao Xiang

Deep learning models for medical image analysis easily suffer from distribution shifts caused by dataset artifacts bias, camera variations, differences in the imaging station, etc., leading to unreliable diagnoses in real-world clinical…

Image and Video Processing · Electrical Eng. & Systems 2024-01-09 Siyuan Yan , Chi Liu , Zhen Yu , Lie Ju , Dwarikanath Mahapatra , Brigid Betz-Stablein , Victoria Mar , Monika Janda , Peter Soyer , Zongyuan Ge

Electrocardiography (ECG) signals are frequently degraded by noise, limiting their clinical reliability in both conventional and wearable settings. Existing methods for addressing ECG noise, relying on artifact classification or denoising,…

Signal Processing · Electrical Eng. & Systems 2025-07-23 Tae-Seong Han , Jae-Wook Heo , Hakseung Kim , Cheol-Hui Lee , Hyub Huh , Eue-Keun Choi , Hye Jin Kim , Dong-Joo Kim

EEG-based analysis of pain perception, enhanced by machine learning, reveals how the brain encodes pain by identifying neural patterns evoked by noxious stimulation. However, a major challenge that remains is the generalization of machine…

Signal Processing · Electrical Eng. & Systems 2025-08-19 Mathis Rezzouk , Fabrice Gagnon , Alyson Champagne , Mathieu Roy , Philippe Albouy , Michel-Pierre Coll , Cem Subakan

Medical Image Analysis (MedIA) has emerged as a crucial tool in computer-aided diagnosis systems, particularly with the advancement of deep learning (DL) in recent years. However, well-trained deep models often experience significant…

Computer Vision and Pattern Recognition · Computer Science 2024-02-14 Ziwei Niu , Shuyi Ouyang , Shiao Xie , Yen-wei Chen , Lanfen Lin

Automated ECG diagnosis has seen significant advancements with deep learning techniques, but real-world applications still face challenges when dealing with scanned paper ECGs. In this study, we explore multi-label classification of ECGs…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Cuong V. Nguyen , Hieu X. Nguyen , Dung D. Pham Minh , Cuong D. Do

The generalization capability of machine learning models, which refers to generalizing the knowledge for an "unseen" domain via learning from one or multiple seen domain(s), is of great importance to develop and deploy machine learning…

Machine Learning · Computer Science 2022-02-17 Keyu Chen , Di Zhuang , J. Morris Chang

Domain adaption (DA) and domain generalization (DG) are two closely related methods which are both concerned with the task of assigning labels to an unlabeled data set. The only dissimilarity between these approaches is that DA can access…

Computer Vision and Pattern Recognition · Computer Science 2018-12-27 Mohammad Mahfujur Rahman , Clinton Fookes , Mahsa Baktashmotlagh , Sridha Sridharan

Domain generalization aims to learn a predictive model from multiple different but related source tasks that can generalize well to a target task without the need of accessing any target data. Existing domain generalization methods ignore…

Machine Learning · Computer Science 2022-06-08 William Wei Wang , Gezheng Xu , Ruizhi Pu , Jiaqi Li , Fan Zhou , Changjian Shui , Charles Ling , Christian Gagné , Boyu Wang

Digitization techniques for biomedical images yield different visual patterns in radiological exams. These differences may hamper the use of data-driven approaches for inference over these images, such as Deep Neural Networks. Another…

Computer Vision and Pattern Recognition · Computer Science 2019-12-10 Hugo Oliveira , Edemir Ferreira , Jefersson A. dos Santos

Electrocardiogram (ECG) biometrics have emerged as a promising modality for continuous, liveness-aware authentication in wearable systems. However, many prior studies report overly optimistic results due to data leakage (e.g., random splits…

Machine Learning · Computer Science 2026-05-05 Milad Parvan

Self-supervised learning has produced impressive results in multimedia domains of audio, vision and speech. This paradigm is equally, if not more, relevant for the domain of biosignals, owing to the scarcity of labelled data in such…

Machine Learning · Computer Science 2024-03-07 Aditya Kommineni , Kleanthis Avramidis , Richard Leahy , Shrikanth Narayanan

Cross-site generalizability in medical AI is fundamentally compromised by selection bias, a structural mechanism where patient demographics (e.g., age, severity) non-randomly dictate hospital assignment. Conventional Domain Generalization…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Shaojin Bai , Yuting Su , Weizhi Nie

Domain Generalization (DG) aims to develop classifiers that can generalize to new, unseen data distributions, a critical capability when collecting new domain-specific data is impractical. A common DG baseline minimizes the empirical risk…

Machine Learning · Computer Science 2024-12-11 Piotr Teterwak , Kuniaki Saito , Theodoros Tsiligkaridis , Kate Saenko , Bryan A. Plummer

Despite the rapid development of machine learning algorithms for domain generalization (DG), there is no clear empirical evidence that the existing DG algorithms outperform the classic empirical risk minimization (ERM) across standard…

Machine Learning · Computer Science 2024-03-19 Rui Qiao , Bryan Kian Hsiang Low

Background:The electrocardiogram (ECG) is one of the most commonly used diagnostic tools in medicine and healthcare. Deep learning methods have achieved promising results on predictive healthcare tasks using ECG signals. Objective:This…

Signal Processing · Electrical Eng. & Systems 2020-05-04 Shenda Hong , Yuxi Zhou , Junyuan Shang , Cao Xiao , Jimeng Sun

Electroencephalography foundation models (EEG-FMs) have advanced brain signal analysis, but the lack of standardized evaluation benchmarks impedes model comparison and scientific progress. Current evaluations rely on inconsistent protocols…

Signal Processing · Electrical Eng. & Systems 2026-02-16 Wei Xiong , Jiangtong Li , Jie Li , Kun Zhu , Changjun Jiang

This paper addresses the persistent challenge of accurately digitizing paper-based electrocardiogram (ECG) recordings, with a particular focus on robustly handling single leads compromised by signal overlaps-a common yet under-addressed…

Machine Learning · Computer Science 2025-06-13 Reza Karbasi , Masoud Rahimi , Abdol-Hossein Vahabie , Hadi Moradi

Electroencephalography (EEG) analysis stands at the forefront of neuroscience and artificial intelligence research, where foundation models are reshaping the traditional EEG analysis paradigm by leveraging their powerful representational…

Human-Computer Interaction · Computer Science 2025-08-25 Hongqi Li , Yitong Chen , Yujuan Wang , Weihang Ni , Haodong Zhang