Related papers: Fluctuation-based deconvolution in fluorescence mi…
Inverse problems generally require a regularizer or prior for a good solution. A recent trend is to train a convolutional net to denoise images, and use this net as a prior when solving the inverse problem. Several proposals depend on a…
The plug-and-play (PnP) method uses a deep denoiser within a proximal algorithm for model-based image reconstruction (IR). Unlike end-to-end IR, PnP allows the same pretrained denoiser to be used across different imaging tasks, without the…
Due to image blurring image deconvolution is often used for studying biological structures in fluorescence microscopy. Fluorescence microscopy image volumes inherently suffer from intensity inhomogeneity, blur, and are corrupted by various…
Advances in microscopy imaging enable researchers to visualize structures at the nanoscale level thereby unraveling intricate details of biological organization. However, challenges such as image noise, photobleaching of fluorophores, and…
There has been tremendous research on the design of image regularizers over the years, from simple Tikhonov and Laplacian to sophisticated sparsity and CNN-based regularizers. Coupled with a model-based loss function, these are typically…
In recent literature there are plenty of works that combine handcrafted and learnable regularizers to solve inverse imaging problems. While this hybrid approach has demonstrated promising results, the motivation for combining handcrafted…
Plug-and-play (PnP) denoising is a popular iterative framework for solving imaging inverse problems using off-the-shelf image denoisers. Their empirical success has motivated a line of research that seeks to understand the convergence of…
Plug-and-Play (PnP) algorithms are a class of iterative algorithms that address image inverse problems by combining a physical model and a deep neural network for regularization. Even if they produce impressive image restoration results,…
Plug-and-Play Priors (PnP) and Regularisation by Denoising (RED) have established that image denoisers can effectively replace traditional regularisers in linear inverse problem solvers for tasks like super-resolution, demosaicing, and…
Non-uniqueness and instability are characteristic features of image reconstruction processes. As a result, it is necessary to develop regularization methods that can be used to compute reliable approximate solutions. A regularization method…
We propose a general framework to recover underlying images from noisy phaseless diffraction measurements based on the alternating directional method of multipliers and the plug-and-play technique. The algorithm consists of three-step…
Microscopy is a powerful visualization tool in biology, enabling the study of cells, tissues, and the fundamental biological processes; yet, the observed images typically suffer from blur and background noise. In this work, we propose a…
In multi-photon microscopy (MPM), a recent in-vivo fluorescence microscopy system, the task of image restoration can be decomposed into two interlinked inverse problems: firstly, the characterization of the Point Spread Function (PSF) and…
Recent frameworks, such as the so-called plug-and-play, allow us to leverage the developments in image denoising to tackle other, and more involved, problems in image processing. As the name suggests, state-of-the-art denoisers are plugged…
Fluorescence microscopy images usually show severe anisotropy in axial versus lateral resolution. This hampers downstream processing, i.e. the automatic extraction of quantitative biological data. While deconvolution methods and other…
We present a method for supervised learning of sparsity-promoting regularizers for image denoising. Sparsity-promoting regularization is a key ingredient in solving modern image reconstruction problems; however, the operators underlying…
In this work, we present new proofs of convergence for Plug-and-Play (PnP) algorithms. PnP methods are efficient iterative algorithms for solving image inverse problems where regularization is performed by plugging a pre-trained denoiser in…
Fluorescence microscopy is a key driver to promote discoveries of biomedical research. However, with the limitation of microscope hardware and characteristics of the observed samples, the fluorescence microscopy images are susceptible to…
We study the problem of deconvolution for light-sheet microscopy, where the data is corrupted by spatially varying blur and a combination of Poisson and Gaussian noise. The spatial variation of the point spread function (PSF) of a…
Image denoising is a classical problem in low level computer vision. Model-based optimization methods and deep learning approaches have been the two main strategies for solving the problem. Model-based optimization methods are flexible for…