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Recent deep learning-based methods have shown promising results and runtime advantages in deformable image registration. However, analyzing the effects of hyperparameters and searching for optimal regularization parameters prove to be too…

Computer Vision and Pattern Recognition · Computer Science 2021-07-06 Tony C. W. Mok , Albert C. S. Chung

In the past, optimization-based registration models have used spatially-varying regularization to account for deformation variations in different image regions. However, deep learning-based registration models have mostly relied on…

Image and Video Processing · Electrical Eng. & Systems 2023-03-14 Junyu Chen , Yihao Liu , Yufan He , Yong Du

Spatially varying regularization accommodates the deformation variations that may be necessary for different anatomical regions during deformable image registration. Historically, optimization-based registration models have harnessed…

Computer Vision and Pattern Recognition · Computer Science 2025-11-21 Junyu Chen , Shuwen Wei , Yihao Liu , Zhangxing Bian , Yufan He , Aaron Carass , Harrison Bai , Yong Du

Image registration is a key technique in medical image analysis to estimate deformations between image pairs. A good deformation model is important for high-quality estimates. However, most existing approaches use ad-hoc deformation models…

Computer Vision and Pattern Recognition · Computer Science 2019-04-23 Marc Niethammer , Roland Kwitt , Francois-Xavier Vialard

We present deformable unsupervised medical image registration using a randomly-initialized deep convolutional neural network (CNN) as regularization prior. Conventional registration methods predict a transformation by minimizing…

Image and Video Processing · Electrical Eng. & Systems 2019-08-05 Max-Heinrich Laves , Sontje Ihler , Tobias Ortmaier

Image registration has traditionally been done using two distinct approaches: learning based methods, relying on robust deep neural networks, and optimization-based methods, applying complex mathematical transformations to warp images…

Computer Vision and Pattern Recognition · Computer Science 2024-01-22 Gabriel De Araujo , Shanlin Sun , Xiaohui Xie

Parametric spatial transformation models have been successfully applied to image registration tasks. In such models, the transformation of interest is parameterized by a fixed set of basis functions as for example B-splines. Each basis…

Computer Vision and Pattern Recognition · Computer Science 2019-06-25 Robin Sandkühler , Simon Andermatt , Grzegorz Bauman , Sylvia Nyilas , Christoph Jud , Philippe C. Cattin

Regularization strategies in medical image registration often take a one-size-fits-all approach by imposing uniform constraints across the entire image domain. Yet biological structures are anything but regular. Lacking structural…

Computer Vision and Pattern Recognition · Computer Science 2025-04-09 Ziad Kheil , Soleakhena Ken , Laurent Risser

We present a fast learning-based algorithm for deformable, pairwise 3D medical image registration. Current registration methods optimize an objective function independently for each pair of images, which can be time-consuming for large…

Computer Vision and Pattern Recognition · Computer Science 2019-03-14 Guha Balakrishnan , Amy Zhao , Mert R. Sabuncu , John Guttag , Adrian V. Dalca

Image registration is fundamental in medical imaging applications, such as disease progression analysis or radiation therapy planning. The primary objective of image registration is to precisely capture the deformation between two or more…

Image and Video Processing · Electrical Eng. & Systems 2024-12-23 Anna Reithmeir , Veronika Spieker , Vasiliki Sideri-Lampretsa , Daniel Rueckert , Julia A. Schnabel , Veronika A. Zimmer

We present an approach to learning regular spatial transformations between image pairs in the context of medical image registration. Contrary to optimization-based registration techniques and many modern learning-based methods, we do not…

Conventional deformable registration methods aim at solving an optimization model carefully designed on image pairs and their computational costs are exceptionally high. In contrast, recent deep learning based approaches can provide fast…

Computer Vision and Pattern Recognition · Computer Science 2021-10-01 Risheng Liu , Zi Li , Xin Fan , Chenying Zhao , Hao Huang , Zhongxuan Luo

Image registration is a process of aligning two or more images of same objects using geometric transformation. Most of the existing approaches work on the assumption of location invariance. These approaches require object-centric images to…

Computer Vision and Pattern Recognition · Computer Science 2019-01-14 Deepak Mishra , Rajeev Ranjan , Santanu Chaudhury , Mukul Sarkar , Arvinder Singh Soin

This paper presents a predictive model for estimating regularization parameters of diffeomorphic image registration. We introduce a novel framework that automatically determines the parameters controlling the smoothness of diffeomorphic…

Image and Video Processing · Electrical Eng. & Systems 2022-02-08 Jian Wang , Miaomiao Zhang

Deformable image registration is a fundamental task in medical image analysis and plays a crucial role in a wide range of clinical applications. Recently, deep learning-based approaches have been widely studied for deformable medical image…

Image and Video Processing · Electrical Eng. & Systems 2023-07-03 Jing Zou , Noémie Debroux , Lihao Liu , Jing Qin , Carola-Bibiane Schönlieb , Angelica I Aviles-Rivero

Multimodal image registration is a challenging but essential step for numerous image-guided procedures. Most registration algorithms rely on the computation of complex, frequently non-differentiable similarity metrics to deal with the…

Computer Vision and Pattern Recognition · Computer Science 2023-07-20 Matteo Ronchetti , Wolfgang Wein , Nassir Navab , Oliver Zettinig , Raphael Prevost

Deformable image registration is a crucial step in medical image analysis for finding a non-linear spatial transformation between a pair of fixed and moving images. Deep registration methods based on Convolutional Neural Networks (CNNs)…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Mingyuan Meng , Lei Bi , Dagan Feng , Jinman Kim

Classical pairwise image registration methods search for a spatial transformation that optimises a numerical measure that indicates how well a pair of moving and fixed images are aligned. Current learning-based registration methods have…

Image and Video Processing · Electrical Eng. & Systems 2019-10-22 Yipeng Hu , Eli Gibson , Dean C. Barratt , Mark Emberton , J. Alison Noble , Tom Vercauteren

In order to tackle the difficulty associated with the ill-posed nature of the image registration problem, regularization is often used to constrain the solution space. For most learning-based registration approaches, the regularization…

Computer Vision and Pattern Recognition · Computer Science 2022-03-03 Zhe Xu , Jie Luo , Donghuan Lu , Jiangpeng Yan , Sarah Frisken , Jayender Jagadeesan , William Wells , Xiu Li , Yefeng Zheng , Raymond Tong

Classical deformable registration techniques achieve impressive results and offer a rigorous theoretical treatment, but are computationally intensive since they solve an optimization problem for each image pair. Recently, learning-based…

Computer Vision and Pattern Recognition · Computer Science 2019-07-26 Adrian V. Dalca , Guha Balakrishnan , John Guttag , Mert R. Sabuncu
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