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Staining is essential in cell imaging and medical diagnostics but poses significant challenges, including high cost, time consumption, labor intensity, and irreversible tissue alterations. Recent advances in deep learning have enabled…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Ziwang Xu , Lanqing Guo , Satoshi Tsutsui , Shuyan Zhang , Alex C. Kot , Bihan Wen

Deep Learning has emerged as a promising approach for skin lesion analysis. However, existing methods mostly rely on fully supervised learning, requiring extensive labeled data, which is challenging and costly to obtain. To alleviate this…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Siyamalan Manivannan

Histopathology can help clinicians make accurate diagnoses, determine disease prognosis, and plan appropriate treatment strategies. As deep learning techniques prove successful in the medical domain, the primary challenges become limited…

Computer Vision and Pattern Recognition · Computer Science 2024-07-11 Zhe Li , Bernhard Kainz

Computational pathology models rarely utilise data that will not be available for inference. This means most models cannot learn from highly informative data such as additional immunohistochemical (IHC) stains and spatial transcriptomics.…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Lucas Farndale , Robert Insall , Ke Yuan

Hyperspectral image (HSI) classification presents unique challenges due to its high spectral dimensionality and limited labeled data. Traditional deep learning models often suffer from overfitting and high computational costs.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Prachet Dev Singh , Shyamsundar Paramasivam , Sneha Barman , Mainak Singha , Ankit Jha , Girish Mishra , Biplab Banerjee

The development of computer vision solutions for gigapixel images in digital pathology is hampered by significant computational limitations due to the large size of whole slide images. In particular, digitizing biopsies at high resolutions…

Computer Vision and Pattern Recognition · Computer Science 2024-01-12 Rocío del Amor , Julio Silva-Rodríguez , Adrián Colomer , Valery Naranjo

Deep learning methods usually require a large amount of training data and lack interpretability. In this paper, we propose a novel knowledge distillation and model interpretation framework for medical image classification that jointly…

Computer Vision and Pattern Recognition · Computer Science 2022-01-13 Thanh Nguyen-Duc , He Zhao , Jianfei Cai , Dinh Phung

Segmenting tumors in histological images is vital for cancer diagnosis. While fully supervised models excel with pixel-level annotations, creating such annotations is labor-intensive and costly. Accurate histopathology image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Yinsheng He , Xingyu Li , Roger J. Zemp

Knowledge distillation allows transferring knowledge from a pre-trained model to another. However, it suffers from limitations, and constraints related to the two models need to be architecturally similar. Knowledge distillation addresses…

Image and Video Processing · Electrical Eng. & Systems 2020-09-03 Sajjad Abbasi , Mohsen Hajabdollahi , Pejman Khadivi , Nader Karimi , Roshanak Roshandel , Shahram Shirani , Shadrokh Samavi

Histological staining is the gold standard for tissue examination in clinical pathology and life-science research, which visualizes the tissue and cellular structures using chromatic dyes or fluorescence labels to aid the microscopic…

Medical Physics · Physics 2023-03-07 Bijie Bai , Xilin Yang , Yuzhu Li , Yijie Zhang , Nir Pillar , Aydogan Ozcan

Deep learning models are prone to learning shortcut solutions to problems using spuriously correlated yet irrelevant features of their training data. In high-risk applications such as medical image analysis, this phenomenon may prevent…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Christopher Boland , Sotirios Tsaftaris , Sonia Dahdouh

The limited availability of labeled data has driven advancements in semi-supervised learning for medical image segmentation. Modern large-scale models tailored for general segmentation, such as the Segment Anything Model (SAM), have…

Computer Vision and Pattern Recognition · Computer Science 2024-12-19 Kaiwen Huang , Tao Zhou , Huazhu Fu , Yizhe Zhang , Yi Zhou , Chen Gong , Dong Liang

Deep learning (DL) based diagnostics systems can provide accurate and robust quantitative analysis in digital pathology. These algorithms require large amounts of annotated training data which is impractical in pathology due to the high…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Tahsin Reasat , Asif Sushmit , David S. Smith

Semi-supervised learning for medical image segmentation presents a unique challenge of efficiently using limited labeled data while leveraging abundant unlabeled data. Despite advancements, existing methods often do not fully exploit the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-12 Bin Zhao , Chunshi Wang , Shuxue Ding

Self-supervised learning has witnessed great progress in vision and NLP; recently, it also attracted much attention to various medical imaging modalities such as X-ray, CT, and MRI. Existing methods mostly focus on building new pretext…

Computer Vision and Pattern Recognition · Computer Science 2022-09-27 Xinpeng Ding , Ziwei Liu , Xiaomeng Li

Dataset distillation aims to compress information from a large-scale original dataset to a new compact dataset while striving to preserve the utmost degree of the original data informational essence. Previous studies have predominantly…

Computer Vision and Pattern Recognition · Computer Science 2024-04-12 Muxin Zhou , Zeyuan Yin , Shitong Shao , Zhiqiang Shen

We investigate omni-supervised learning, a special regime of semi-supervised learning in which the learner exploits all available labeled data plus internet-scale sources of unlabeled data. Omni-supervised learning is lower-bounded by…

Computer Vision and Pattern Recognition · Computer Science 2017-12-13 Ilija Radosavovic , Piotr Dollár , Ross Girshick , Georgia Gkioxari , Kaiming He

Real-world contains an overwhelmingly large number of object classes, learning all of which at once is infeasible. Few shot learning is a promising learning paradigm due to its ability to learn out of order distributions quickly with only a…

Computer Vision and Pattern Recognition · Computer Science 2020-08-05 Jathushan Rajasegaran , Salman Khan , Munawar Hayat , Fahad Shahbaz Khan , Mubarak Shah

Performance of deep learning algorithms decreases drastically if the data distributions of the training and testing sets are different. Due to variations in staining protocols, reagent brands, and habits of technicians, color variation in…

Computer Vision and Pattern Recognition · Computer Science 2020-12-01 Abhijeet Patil , Mohd. Talha , Aniket Bhatia , Nikhil Cherian Kurian , Sammed Mangale , Sunil Patel , Amit Sethi

Medical image enhancement is clinically valuable, but existing methods require large-scale datasets to learn complex pixel-level mappings. However, the substantial training and storage costs associated with these datasets hinder their…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Fengzhi Xu , Ziyuan Yang , Mengyu Sun , Joey Tianyi Zhou , Yi Zhang
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