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Histology analysis of the tumor micro-environment integrated with genomic assays is the gold standard for most cancers in modern medicine. This paper proposes a Gene-induced Multimodal Pre-training (GiMP) framework, which jointly…

Computer Vision and Pattern Recognition · Computer Science 2023-09-07 Ting Jin , Xingran Xie , Renjie Wan , Qingli Li , Yan Wang

In Sub-Saharan Africa (SSA), the utilization of lower-quality Magnetic Resonance Imaging (MRI) technology raises questions about the applicability of machine learning methods for clinical tasks. This study aims to provide a robust deep…

Image and Video Processing · Electrical Eng. & Systems 2025-01-10 Rancy Chepchirchir , Jill Sunday , Raymond Confidence , Dong Zhang , Talha Chaudhry , Udunna C. Anazodo , Kendi Muchungi , Yujing Zou

Neurofibromatosis Type 1 is a genetic disorder characterized by the development of neurofibromas (NFs), which exhibit significant variability in size, morphology, and anatomical location. Accurate and automated segmentation of these tumors…

Image and Video Processing · Electrical Eng. & Systems 2025-11-18 Georgii Kolokolnikov , Marie-Lena Schmalhofer , Lennart Well , Said Farschtschi , Victor-Felix Mautner , Inka Ristow , Rene Werner

A brain tumor, whether benign or malignant, can potentially be life threatening and requires painstaking efforts in order to identify the type, origin and location, let alone cure one. Manual segmentation by medical specialists can be…

Image and Video Processing · Electrical Eng. & Systems 2023-05-02 Ayan Gupta , Mayank Dixit , Vipul Kumar Mishra , Attulya Singh , Atul Dayal

Background and aim: This study aimed to predict methylation status of the O-6 methyl guanine-DNA methyl transferase (MGMT) gene promoter status by using MRI radiomics features, as well as univariate and multivariate analysis. Material and…

Medical image segmentation is a critical achievement in modern medical science, developed over decades of research. It allows for the exact delineation of anatomical and pathological features in two- or three-dimensional pictures by…

Image and Video Processing · Electrical Eng. & Systems 2025-11-06 Chukwuemeka Arua Kalu , Adaobi Chiazor Emegoakor , Fortune Okafor , Augustine Okoh Uchenna , Chijioke Kelvin Ukpai , Godsent Erere Onyeugbo

Surgery for gliomas (intrinsic brain tumors), especially when low-grade, is challenging due to the infiltrative nature of the lesion. Currently, no real-time, intra-operative, label-free and wide-field tool is available to assist and guide…

Segmentation of colorectal cancerous regions from 3D Magnetic Resonance (MR) images is a crucial procedure for radiotherapy which conventionally requires accurate delineation of tumour boundaries at an expense of labor, time and…

Computer Vision and Pattern Recognition · Computer Science 2021-05-25 Yi-Jie Huang , Qi Dou , Zi-Xian Wang , Li-Zhi Liu , Ying Jin , Chao-Feng Li , Lisheng Wang , Hao Chen , Rui-Hua Xu

Gliomas are the most common malignant brain tumors that are treated with chemoradiotherapy and surgery. Magnetic Resonance Imaging (MRI) is used by radiotherapists to manually segment brain lesions and to observe their development…

Image and Video Processing · Electrical Eng. & Systems 2020-11-30 Jonas Wacker , Marcelo Ladeira , José Eduardo Vaz Nascimento

Detection of brain tumor using a segmentation based approach is critical in cases, where survival of a subject depends on an accurate and timely clinical diagnosis. Gliomas are the most commonly found tumors having irregular shape and…

Computer Vision and Pattern Recognition · Computer Science 2018-04-16 Saddam Hussain , Syed Muhammad Anwar , Muhammad Majid

Purpose; The purpose of this study is to classify glial tumors into grade II, III and IV categories noninvasively by application of machine learning to multi-modal MRI features in comparison with volumetric analysis. Methods; We…

Image and Video Processing · Electrical Eng. & Systems 2022-08-16 Sevcan Turk , Kaya Oguz , Mehmet Orman , Emre Caliskan , Yesim Ertan , Erkin Ozgiray , Taner Akalin , Ashok Srinivasan , Omer Kitis

We present an Expectation-Maximization (EM) Regularized Deep Learning (EMReDL) model for weakly supervised tumor segmentation. The proposed framework is tailored to glioblastoma, a type of malignant tumor characterized by its diffuse…

Image and Video Processing · Electrical Eng. & Systems 2021-07-16 Chao Li , Wenjian Huang , Xi Chen , Yiran Wei , Stephen J. Price , Carola-Bibiane Schönlieb

Glioblastoma is profoundly heterogeneous in regional microstructure and vasculature. Characterizing the spatial heterogeneity of glioblastoma could lead to more precise treatment. With unsupervised learning techniques, glioblastoma…

Machine Learning · Computer Science 2021-08-24 Yifan Li , Chao Li , Yiran Wei , Stephen Price , Carola-Bibiane Schönlieb , Xi Chen

Automatic segmentation of fine-grained brain structures remains a challenging task. Current segmentation methods mainly utilize 2D and 3D deep neural networks. The 2D networks take image slices as input to produce coarse segmentation in…

Computer Vision and Pattern Recognition · Computer Science 2019-05-08 Yuemeng Li , Hangfan Liu , Hongming Li , Yong Fan

The task of medical image segmentation presents unique challenges, necessitating both localized and holistic semantic understanding to accurately delineate areas of interest, such as critical tissues or aberrant features. This complexity is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Pranav Singh , Luoyao Chen , Mei Chen , Jinqian Pan , Raviteja Chukkapalli , Shravan Chaudhari , Jacopo Cirrone

Magnetic resonance imaging (MRI) is routinely used for brain tumor diagnosis, treatment planning, and post-treatment surveillance. Recently, various models based on deep neural networks have been proposed for the pixel-level segmentation of…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Daniel E. Cahall , Ghulam Rasool , Nidhal C. Bouaynaya , Hassan M. Fathallah-Shaykh

In this paper, we use a fully convolutional neural network (FCNN) for the segmentation of gliomas from Magnetic Resonance Images (MRI). A fully automatic, voxel based classification was achieved by training a 23 layer deep FCNN on 2-D…

Computer Vision and Pattern Recognition · Computer Science 2017-12-07 Varghese Alex , Mohammed Safwan , Ganapathy Krishnamurthi

Over half a million individuals are diagnosed with head and neck cancer each year worldwide. Radiotherapy is an important curative treatment for this disease, but it requires manual time consuming delineation of radio-sensitive organs at…

Outcome prediction is crucial for head and neck cancer patients as it can provide prognostic information for early treatment planning. Radiomics methods have been widely used for outcome prediction from medical images. However, these…

Image and Video Processing · Electrical Eng. & Systems 2023-03-21 Mingyuan Meng , Lei Bi , Dagan Feng , Jinman Kim

Background: Gliomas are among the most common malignant brain tumors and exhibit substantial heterogeneity, complicating accurate detection and segmentation. Although multi-modal MRI is the clinical standard for glioma imaging, variability…

Image and Video Processing · Electrical Eng. & Systems 2026-01-05 Yanbing Chen , Tianze Tang , Taehyo Kim , Hai Shu