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Transformers have made remarkable progress towards modeling long-range dependencies within the medical image analysis domain. However, current transformer-based models suffer from several disadvantages: (1) existing methods fail to capture…

Computer Vision and Pattern Recognition · Computer Science 2022-12-16 Chenyu You , Ruihan Zhao , Fenglin Liu , Siyuan Dong , Sandeep Chinchali , Ufuk Topcu , Lawrence Staib , James S. Duncan

Although multiple instance learning (MIL) methods are widely used for automatic tumor detection on whole slide images (WSI), they suffer from the extreme class imbalance within the small tumor WSIs. This occurs when the tumor comprises only…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Ziyu Su , Mostafa Rezapour , Usama Sajjad , Shuo Niu , Metin Nafi Gurcan , Muhammad Khalid Khan Niazi

Transformer has been widely used in histopathology whole slide image (WSI) classification for the purpose of tumor grading, prognosis analysis, etc. However, the design of token-wise self-attention and positional embedding strategy in the…

Computer Vision and Pattern Recognition · Computer Science 2022-06-28 Yushan Zheng , Jun Li , Jun Shi , Fengying Xie , Zhiguo Jiang

Accurate diagnosis of breast cancer in histopathology images is challenging due to the heterogeneity of cancer cell growth as well as of a variety of benign breast tissue proliferative lesions. In this paper, we propose a practical and…

Computer Vision and Pattern Recognition · Computer Science 2020-05-06 Xingyu Li , Marko Radulovic , Ksenija Kanjer , Konstantinos N. Plataniotis

The task of Stance Detection involves discerning the stance expressed in a text towards a specific subject or target. Prior works have relied on existing transformer models that lack the capability to prioritize targets effectively.…

Computation and Language · Computer Science 2024-10-10 Krishna Garg , Cornelia Caragea

Deep learning has achieved remarkable success in medical image analysis, yet its performance remains highly sensitive to the heterogeneity of clinical data. Differences in imaging hardware, staining protocols, and acquisition conditions…

Image and Video Processing · Electrical Eng. & Systems 2026-03-18 Callen MacPhee , Yiming Zhou , Koichiro Kishima , Bahram Jalali

Liver tumor segmentation and classification are important tasks in computer aided diagnosis. We aim to address three problems: liver tumor screening and preliminary diagnosis in non-contrast computed tomography (CT), and differential…

Image and Video Processing · Electrical Eng. & Systems 2023-10-24 Ke Yan , Xiaoli Yin , Yingda Xia , Fakai Wang , Shu Wang , Yuan Gao , Jiawen Yao , Chunli Li , Xiaoyu Bai , Jingren Zhou , Ling Zhang , Le Lu , Yu Shi

The task of classifying mammograms is very challenging because the lesion is usually small in the high resolution image. The current state-of-the-art approaches for medical image classification rely on using the de-facto method for ConvNets…

Computer Vision and Pattern Recognition · Computer Science 2021-01-21 Tao Wei , Angelica I Aviles-Rivero , Shuo Wang , Yuan Huang , Fiona J Gilbert , Carola-Bibiane Schönlieb , Chang Wen Chen

In this paper, we report a hidden Markov model based multiclass classification of cervical cancer tissues. This model has been validated directly over time series generated by the medium refractive index fluctuations extracted from…

Computer Vision and Pattern Recognition · Computer Science 2016-12-06 Sabyasachi Mukhopadhyay , Sanket Nandan , Indrajit Kurmi

Background: Cervical cancer seriously affects the health of the female reproductive system. Optical coherence tomography (OCT) emerged as a non-invasive, high-resolution imaging technology for cervical disease detection. However, OCT image…

Image and Video Processing · Electrical Eng. & Systems 2022-06-14 Kaiyi Chen , Qingbin Wang , Yutao Ma

Motion prediction is an important aspect for Autonomous Driving (AD) and Advance Driver Assistance Systems (ADAS). Current state-of-the-art motion prediction methods rely on High Definition (HD) maps for capturing the surrounding context of…

Machine Learning · Computer Science 2025-04-15 Harsh Yadav , Maximilian Schaefer , Kun Zhao , Tobias Meisen

The classification of gigapixel histopathology images with deep multiple instance learning models has become a critical task in digital pathology and precision medicine. In this work, we propose a Transformer-based multiple instance…

Computer Vision and Pattern Recognition · Computer Science 2023-11-21 Josef Cersovsky , Sadegh Mohammadi , Dagmar Kainmueller , Johannes Hoehne

Transformer plays a central role in many fundamental deep learning models, e.g., the ViT in computer vision and the BERT and GPT in natural language processing, whose effectiveness is mainly attributed to its multi-head attention (MHA)…

Machine Learning · Computer Science 2024-10-16 Shen Yuan , Hongteng Xu

Human papillomavirus (HPV) status is a critical determinant of prognosis and treatment response in head and neck and cervical cancers. Although attention-based multiple instance learning (MIL) achieves strong slide-level prediction for…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Weiyi Qin , Yingci Liu-Swetz , Shiwei Tan , Hao Wang

Breast cancer treatment still remains a challenge, where molecular subtypes classification plays a crucial role in selecting appropriate and specific therapy. The four subtypes are Luminal A (LA), Luminal B (LB), HER2 subtype, and…

Machine Learning · Computer Science 2023-10-24 Matheus del-Valle , Emerson Soares Bernardes , Denise Maria Zezell

Breast cancer screening, primarily conducted through mammography, is often supplemented with ultrasound for women with dense breast tissue. However, existing deep learning models analyze each modality independently, missing opportunities to…

Image and Video Processing · Electrical Eng. & Systems 2023-11-16 Yiqiu Shen , Jungkyu Park , Frank Yeung , Eliana Goldberg , Laura Heacock , Farah Shamout , Krzysztof J. Geras

In recent years, transformer-based methods have achieved remarkable progress in medical image segmentation due to their superior ability to capture long-range dependencies. However, these methods typically suffer from two major limitations.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Zunhui Xia , Hongxing Li , Libin Lan

Breast cancer has long been a prominent cause of mortality among women. Diagnosis, therapy, and prognosis are now possible, thanks to the availability of RNA sequencing tools capable of recording gene expression data. Molecular subtyping…

Machine Learning · Computer Science 2021-11-11 Sheetal Rajpal , Virendra Kumar , Manoj Agarwal , Naveen Kumar

Colorectal cancer (CRC) ranks as the second leading cause of cancer-related deaths and the third most prevalent malignant tumour worldwide. Early detection of CRC remains problematic due to its non-specific and often embarrassing symptoms,…

Machine Learning · Computer Science 2025-04-25 Natalia Sikora , Robert L. Manschke , Alethea M. Tang , Peter Dunstan , Dean A. Harris , Su Yang

Over the past decade, convolutional neural networks (CNN) have shown very competitive performance in medical image analysis tasks, such as disease classification, tumor segmentation, and lesion detection. CNN has great advantages in…

Computer Vision and Pattern Recognition · Computer Science 2021-03-11 Yin Dai , Yifan Gao