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Mammography-based screening has helped reduce the breast cancer mortality rate, but has also been associated with potential harms due to low specificity, leading to unnecessary exams or procedures, and low sensitivity. Digital breast…

Despite that deep learning (DL) methods have presented tremendous potential in many medical image analysis tasks, the practical applications of medical DL models are limited due to the lack of enough data samples with manual annotations. By…

Deep neural networks are easily attacked by imperceptible perturbation. Presently, adversarial training (AT) is the most effective method to enhance the robustness of the model against adversarial examples. However, because adversarial…

We present a deep learning strategy that enables, for the first time, contrast-agnostic semantic segmentation of completely unpreprocessed brain MRI scans, without requiring additional training or fine-tuning for new modalities. Classical…

Traditional model-based image reconstruction (MBIR) methods combine forward and noise models with simple object priors. Recent application of deep learning methods for image reconstruction provides a successful data-driven approach to…

Purpose: To develop and assess a deep learning (DL) pipeline to learn dynamic MR image reconstruction from publicly available natural videos (Inter4K). Materials and Methods: Learning was performed for a range of DL architectures (VarNet,…

Computed tomography (CT) is widely used in screening, diagnosis, and image-guided therapy for both clinical and research purposes. Since CT involves ionizing radiation, an overarching thrust of related technical research is development of…

Distribution shifts are problems where the distribution of data changes between training and testing, which can significantly degrade the performance of a model deployed in the real world. Recent studies suggest that one reason for the…

In MRI, variations in scan parameters, sequence, or hardware can lead to discrepancies in image appearance, even for the same subject. These inconsistencies, known as domain shifts, can hinder image analysis and degrade the performance of…

Computer-aided detection systems based on deep learning have shown great potential in breast cancer detection. However, the lack of domain generalization of artificial neural networks is an important obstacle to their deployment in changing…

Recent studies show that deep learning (DL) based MRI reconstruction outperforms conventional methods, such as parallel imaging and compressed sensing (CS), in multiple applications. Unlike CS that is typically implemented with…

Magnetic Resonance Imaging (MRI) is considered the gold standard of medical imaging because of the excellent soft-tissue contrast exhibited in the images reconstructed by the MRI pipeline, which in-turn enables the human radiologist to…

Accurate segmentation of retinal fluids in 3D Optical Coherence Tomography images is key for diagnosis and personalized treatment of eye diseases. While deep learning has been successful at this task, trained supervised models often fail…

Deep learning (DL) methods for white matter lesion (WML) segmentation in MRI suffer a reduction in performance when applied on data from a scanner or centre that is out-of-distribution (OOD) from the training data. This is critical for…

Deep learning (DL) has been increasingly applied in medical imaging, however, it requires large amounts of data, which raises many challenges related to data privacy, storage, and transfer. Federated learning (FL) is a training paradigm…

Head computed tomography (CT) imaging is a widely-used imaging modality with multitudes of medical indications, particularly in assessing pathology of the brain, skull, and cerebrovascular system. It is commonly the first-line imaging in…

Deep learning (DL) applied to breast tissue segmentation in magnetic resonance imaging (MRI) has received increased attention in the last decade, however, the domain shift which arises from different vendors, acquisition protocols, and…

Building accurate Deep Learning (DL) models for brain age prediction is a very relevant topic in neuroimaging, as it could help better understand neurodegenerative disorders and find new biomarkers. To estimate accurate and generalizable…

Low-dose computed tomography (CT) denoising algorithms aim to enable reduced patient dose in routine CT acquisitions while maintaining high image quality. Recently, deep learning~(DL)-based methods were introduced, outperforming…

Brain segmentation from neonatal MRI images is a very challenging task due to large changes in the shape of cerebral structures and variations in signal intensities reflecting the gestational process. In this context, there is a clear need…