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For many patients, current ovarian cancer treatments offer limited clinical benefit. For some therapies, it is not possible to predict patients' responses, potentially exposing them to the adverse effects of treatment without any…

Image and Video Processing · Electrical Eng. & Systems 2023-10-20 Jack Breen , Katie Allen , Kieran Zucker , Geoff Hall , Nishant Ravikumar , Nicolas M. Orsi

Accurate and scalable cancer diagnosis remains a critical challenge in modern pathology, particularly for malignancies such as breast, prostate, bone, and cervical, which exhibit complex histological variability. In this study, we propose a…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Faisal Ahmed

Breast cancer is one of the leading fatal disease worldwide with high risk control if early discovered. Conventional method for breast screening is x-ray mammography, which is known to be challenging for early detection of cancer lesions.…

Computer Vision and Pattern Recognition · Computer Science 2020-03-11 Essam A. Rashed , M. Samir Abou El Seoud

Deep learning can promote the mammography-based computer-aided diagnosis (CAD) for breast cancers, but it generally suffers from the small sample size problem. Self-supervised learning (SSL) has shown its effectiveness in medical image…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Ronglin Gong , Jun Wang , Jun Shi

Purpose: The scarcity of high-quality curated labeled medical training data remains one of the major limitations in applying artificial intelligence (AI) systems to breast cancer diagnosis. Deep models for mammogram analysis and mass (or…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Han Chen , Anne L. Martel

In this study, we proposed a deep Swin-Vision Transformer-based transfer learning architecture for robust multi-cancer histopathological image classification. The proposed framework integrates a hierarchical Swin Transformer with…

Image and Video Processing · Electrical Eng. & Systems 2026-04-13 Muazzem Hussain Khan , Tasdid Hasnain , Md. Jamil khan , Ruhul Amin , Md. Shamim Reza , Md. Al Mehedi Hasan , Md Ashad Alam

In routine colorectal cancer management, histologic samples stained with hematoxylin and eosin are commonly used. Nonetheless, their potential for defining objective biomarkers for patient stratification and treatment selection is still…

Quantitative Methods · Quantitative Biology 2024-09-26 Fabi Prezja , Leevi Annala , Sampsa Kiiskinen , Suvi Lahtinen , Timo Ojala , Pekka Ruusuvuori , Teijo Kuopio

Deep learning-based computer-aided diagnosis has achieved unprecedented performance in breast cancer detection. However, most approaches are computationally intensive, which impedes their broader dissemination in real-world applications. In…

Image and Video Processing · Electrical Eng. & Systems 2022-01-14 Jiaqiao Shi , Aleksandar Vakanski , Min Xian , Jianrui Ding , Chunping Ning

Breast cancer is one of the leading causes of female mortality in the world. This can be reduced when diagnoses are performed at the early stages of progression. Further, the efficiency of the process can be significantly improved with…

Image and Video Processing · Electrical Eng. & Systems 2022-02-15 Aravind Ravi

Histopathological images contain rich phenotypic information that can be used to monitor underlying mechanisms contributing to diseases progression and patient survival outcomes. Recently, deep learning has become the mainstream…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Chetan L. Srinidhi , Ozan Ciga , Anne L. Martel

Histology imaging is an important tool in medical diagnosis and research, enabling the examination of tissue structure and composition at the microscopic level. Understanding the underlying molecular mechanisms of tissue architecture is…

Computer Vision and Pattern Recognition · Computer Science 2023-10-30 Ronald Xie , Kuan Pang , Sai W. Chung , Catia T. Perciani , Sonya A. MacParland , Bo Wang , Gary D. Bader

Breast cancer is one of the most threatening diseases in women's life; thus, the early and accurate diagnosis plays a key role in reducing the risk of death in a patient's life. Mammography stands as the reference technique for breast…

Machine Learning · Computer Science 2023-05-05 Juan Zuluaga-Gomez

Breast cancer is one of the most common types of cancer and leading cancer-related death causes for women. In the context of ICIAR 2018 Grand Challenge on Breast Cancer Histology Images, we compare one handcrafted feature extractor and five…

Computer Vision and Pattern Recognition · Computer Science 2018-04-02 Hongliu Cao , Simon Bernard , Laurent Heutte , Robert Sabourin

Accurate detection of cancer tissue regions (CTR) enables deeper analysis of the tumor microenvironment and offers crucial insights into treatment response. Traditional CTR detection methods, which typically rely on the rich cellular…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Shuailin Xue , Jun Wan , Lihua Zhang , Wenwen Min

The rapid development of digital pathology and modern deep learning has facilitated the emergence of pathology foundation models that are expected to solve general pathology problems under various disease conditions in one unified model,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-10 Yutong Sun , Sichen Zhu , Peng Qiu

This paper explores the problem of breast tissue classification of microscopy images. Based on the predominant cancer type the goal is to classify images into four categories of normal, benign, in situ carcinoma, and invasive carcinoma.…

Computer Vision and Pattern Recognition · Computer Science 2018-06-29 Kamyar Nazeri , Azad Aminpour , Mehran Ebrahimi

We present a self-supervised algorithm for several classification tasks within hematoxylin and eosin (H&E) stained images of breast cancer. Our method is robust to stain variations inherent to the histology images acquisition process, which…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Alexandre Tiard , Alex Wong , David Joon Ho , Yangchao Wu , Eliram Nof , Alvin C. Goh , Stefano Soatto , Saad Nadeem

Artificial intelligence methods including deep neural networks (DNN) can provide rapid molecular classification of tumors from routine histology with accuracy that matches or exceeds human pathologists. Discerning how neural networks make…

Diagnosis of breast carcinomas has so far been limited to the morphological interpretation of epithelial cells and the assessment of epithelial tissue architecture. Consequently, most of the automated systems have focused on characterizing…

Computer Vision and Pattern Recognition · Computer Science 2017-02-21 Babak Ehteshami Bejnordi , Jimmy Linz , Ben Glass , Maeve Mullooly , Gretchen L Gierach , Mark E Sherman , Nico Karssemeijer , Jeroen van der Laak , Andrew H Beck

Spatial transcriptomics enables interrogating the molecular composition of tissue with ever-increasing resolution and sensitivity. However, costs, rapidly evolving technology, and lack of standards have constrained computational methods in…

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