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Generating a novel and optimized molecule with desired chemical properties is an essential part of the drug discovery process. Failure to meet one of the required properties can frequently lead to failure in a clinical test which is costly.…

Machine Learning · Computer Science 2020-10-28 Bonggun Shin , Sungsoo Park , JinYeong Bak , Joyce C. Ho

3D beamforming is a promising approach for interference coordination in cellular networks which brings significant improvements in comparison with conventional 2D beamforming techniques. This paper investigates the problem of joint…

Information Theory · Computer Science 2017-01-16 Soheil Khavari Moghaddam , S. Mohammad Razavizadeh

We present a comprehensive analysis of coherence properties of the radiation from X-ray free electron laser (XFEL). We consider practically important case when XFEL is optimized for maximum gain. Such an optimization allows to reduce…

Accelerator Physics · Physics 2007-05-23 E. L. Saldin , E. A. Schneidmiller , M. V. Yurkov

We put forward a method to optimize the step-tapering amplitude of undulator strength and initial energy detuning of electron beam with the goal of maximizing the saturation power of high-gain FELs, based on the physics of longitudinal…

Accelerator Physics · Physics 2014-03-03 Li Heting , Jia Qika

The generation of X-rays and {\gamma}-rays based on synchrotron radiation from free electrons, emitted in magnet arrays such as undulators, forms the basis of much of modern X-ray science. This approach has the drawback of requiring very…

X-ray free electron lasers (XFELs) are the new generation of particle accelerator-based light sources, capable of producing tunable, high-power X-ray pulses that are increasingly vital across various scientific disciplines. Recently,…

Accelerator Physics · Physics 2025-02-03 Liuyang Wu , Zihan Zhu , Bingyang Yan , Jiawei Yan , Haixiao Deng

Pump-probe experiments combining pulses from a X-ray FEL and an optical femtosecond laser are very attractive for sub-picosecond time-resolved studies. Since the synchronization between the two independent light sources to an accuracy of…

Accelerator Physics · Physics 2009-11-10 J. Feldhaus , M. Koerfer , T. Moeller , J. Pflueger , E. L. Saldin , E. A. Schneidmiller , S. Schreiber , M. V. Yurkov

This paper discusses the potential for enhancing the LCLS hard X-ray FEL capabilities. In the hard X-ray regime, a high longitudinal coherence will be the key to such performance upgrade. The method considered here to obtain high…

Accelerator Physics · Physics 2010-08-19 Gianluca Geloni , Vitali Kocharyan , Evgeni Saldin

Resonant inelastic x-ray scattering (RIXS) is a widely used spectroscopic technique, providing access to the electronic structure and dynamics of atoms, molecules, and solids. However, RIXS requires a narrow bandwidth x-ray probe to achieve…

The high gradients potentially achievable in distributed-coupling C-band photoinjectors make them attractive for many high brightness applications. Here we discuss optimization results for a 1.6 cell C-band photoinjector with a 240 MV/m…

Accelerator Physics · Physics 2025-09-16 M. Kaemingk , P. M. Anisimov , J. M. Maxson , J. B. Rosenzweig , E. I. Simakov , H. Xu

Traditional snapshot hyperspectral imaging systems generally require multiple refractive-optics-based elements to modulate light, resulting in bulky framework. In pursuit of a more compact form factor, a metasurface-based snapshot…

Optics · Physics 2022-11-29 Qiangbo Zhang , Zeqing Yu , Xinyu Liu , Chang Wang , Zhenrong Zheng

Harmonic lasing provides an opportunity to extend the photon energy range of existing and planned X-ray FEL user facilities. Contrary to nonlinear harmonic generation, harmonic lasing can generate a much more intense, stable, and…

The possibility of constructing terawatt (TW) x-ray free-electron lasers (FELs) has been discussed using novel superconducting helical undulators [5]. In this paper, we consider the conditions necessary for achieving powers in excess of 1…

Accelerator Physics · Physics 2018-08-01 H. P. Freund , P. J. M. van der SLot

Free Electron Lasers (FEL) are commonly regarded as the potential key application of laser wakefield accelerators (LWFA). It has been found that electron bunches exiting from state-of-the-art LWFAs exhibit a normalized 6-dimensional beam…

Compact coherent x-ray sources have been the focus of extensive research efforts over the past decades. As a result, several novel schemes like optical and nano-undulators for generating x-ray emissions in "table-top" setups are proposed,…

Accelerator Physics · Physics 2021-12-01 Arya Fallahi , Niels Kuster , Lukas Novotny

The incorporation of high-performance optoelectronic devices into photonic neuromorphic processors can substantially accelerate computationally intensive operations in machine learning (ML) algorithms. However, the conventional device…

Emerging Technologies · Computer Science 2022-03-14 Yingheng Tang , Princess Tara Zamani , Ruiyang Chen , Jianzhu Ma , Minghao Qi , Cunxi Yu , Weilu Gao

The purified SASE (pSASE) undulator configuration recently proposed at SLAC promises an increase in the output spectral density of XFELs. In this article we study a straightforward implementation of this configuration for the soft x-ray…

Accelerator Physics · Physics 2013-08-02 Svitozar Serkez , Vitali Kocharyan , Evgeni Saldin , Igor Zagorodnov , Gianluca Geloni

In this paper, we consider a wireless powered multi-relay network in which a multi-antenna hybrid access point underlaying a cellular system transmits information to distant receivers. Multiple relays capable of energy harvesting are…

Information Theory · Computer Science 2018-10-23 Jing Xu , Yuze Zou , Shimin Gong , Lin Gao , Dusit Niyato , Wenqing Cheng

The regenerative capabilities of next-generation satellite systems offer a novel approach to design low earth orbit (LEO) satellite communication systems, enabling full flexibility in bandwidth and spot beam management, power control, and…

Information Theory · Computer Science 2023-12-19 Sovit Bhandari , Thang X. Vu , Symeon Chatzinotas

A deep understanding of molecular photo-transformations is challenging because of the complex interaction between the configurations of electrons and nuclei. An initial optical excitation dissipates energy into electronic and structural…