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AI in Medical Imaging project aims to enhance the National Cancer Institute's (NCI) Image Data Commons (IDC) by developing nnU-Net models and providing AI-assisted segmentations for cancer radiology images. We created high-quality,…

The National Cancer Institute (NCI) Image Data Commons (IDC) offers publicly available cancer radiology collections for cloud computing, crucial for developing advanced imaging tools and algorithms. Despite their potential, these…

Evaluation of artificial intelligence (AI) models for low-dose CT lung cancer screening is limited by heterogeneous datasets, annotation standards, and evaluation protocols, making performance difficult to compare and translate across…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Fakrul Islam Tushar , Avivah Wang , Lavsen Dahal , Ehsan Samei , Michael R. Harowicz , Jayashree Kalpathy-Cramer , Kyle J. Lafata , Tina D. Tailor , Cynthia Rudin , Joseph Y. Lo

Concerns about the reproducibility of deep learning research are more prominent than ever, with no clear solution in sight. The relevance of machine learning research can only be improved if we also employ empirical rigor that incorporates…

Machine Learning · Computer Science 2022-10-21 Attila Simko , Anders Garpebring , Joakim Jonsson , Tufve Nyholm , Tommy Löfstedt

The early detection and nuanced subtype classification of non-small cell lung cancer (NSCLC), a predominant cause of cancer mortality worldwide, is a critical and complex issue. In this paper, we introduce an innovative integration of…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Salma Hassan , Hamad Al Hammadi , Ibrahim Mohammed , Muhammad Haris Khan

In recent years, the research community has raised serious questions about the reproducibility of scientific work. In particular, since many studies include some kind of computing work, reproducibility is also a technological challenge, not…

Software Engineering · Computer Science 2023-08-03 Lázaro Costa , Susana Barbosa , Jácome Cunha

Public imaging datasets are critical for the development and evaluation of automated tools in cancer imaging. Unfortunately, many do not include annotations or image-derived features, complicating their downstream analysis. Artificial…

Computer Vision and Pattern Recognition · Computer Science 2023-06-02 Deepa Krishnaswamy , Dennis Bontempi , Vamsi Thiriveedhi , Davide Punzo , David Clunie , Christopher P Bridge , Hugo JWL Aerts , Ron Kikinis , Andrey Fedorov

Accurate prognosis of non-small cell lung cancer (NSCLC) patients undergoing immunotherapy is essential for personalized treatment planning, enabling informed patient decisions, and improving both treatment outcomes and quality of life.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-22 Qilong Xing , Zikai Song , Bingxin Gong , Lian Yang , Junqing Yu , Wei Yang

MRI-based medical imaging has become indispensable in modern clinical diagnosis, particularly for brain tumor detection. However, the rapid growth in data volume poses challenges for conventional diagnostic approaches. Although deep…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Hayder Saad Abdulbaqi , Mohammed Hadi Rahim , Mohammed Hassan Hadi , Haider Ali Aboud , Ali Hussein Allawi

Computational pathology, integrating computational methods and digital imaging, has shown to be effective in advancing disease diagnosis and prognosis. In recent years, the development of machine learning and deep learning has greatly…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Jiamu Wang , Chang-Su Kim , Jin Tae Kwak

We describe a project-based introduction to reproducible and collaborative neuroimaging analysis. Traditional teaching on neuroimaging usually consists of a series of lectures that emphasize the big picture rather than the foundations on…

Other Statistics · Statistics 2018-10-23 K. Jarrod Millman , Matthew Brett , Ross Barnowski , Jean-Baptiste Poline

Consistency and duplicability in Computed Tomography (CT) output is essential to quantitative imaging for lung cancer detection and monitoring. This study of CT-detected lung nodules investigated the reproducibility of volume-, density-,…

In cancer research, clustering techniques are widely used for exploratory analyses and dimensionality reduction, playing a critical role in the identification of novel cancer subtypes, often with direct implications for patient management.…

We introduce a new AI-ready computational pathology dataset containing restained and co-registered digitized images from eight head-and-neck squamous cell carcinoma patients. Specifically, the same tumor sections were stained with the…

Image and Video Processing · Electrical Eng. & Systems 2023-05-29 Parmida Ghahremani , Joseph Marino , Juan Hernandez-Prera , Janis V. de la Iglesia , Robbert JC Slebos , Christine H. Chung , Saad Nadeem

Computational pathology is part of precision oncology medicine. The integration of high-throughput data including genomics, transcriptomics, proteomics, metabolomics, pathomics, and radiomics into clinical practice improves cancer treatment…

Image and Video Processing · Electrical Eng. & Systems 2022-06-07 Liangrui Pan , Zhichao Feng , Shaoliang Peng

The Imaging Data Commons (IDC) is a cloud-based database that provides researchers with open access to cancer imaging data, with the goal of facilitating collaboration. However, cohort discovery within the IDC database has a significant…

Machine Learning · Computer Science 2023-11-28 Pranav Kulkarni , Adway Kanhere , Paul H. Yi , Vishwa S. Parekh

We present a hybrid algorithm to estimate lung nodule malignancy that combines imaging biomarkers from Radiologist's annotation with image classification of CT scans. Our algorithm employs a 3D Convolutional Neural Network (CNN) as well as…

Image and Video Processing · Electrical Eng. & Systems 2020-10-23 Kushal Mehta , Arshita Jain , Jayalakshmi Mangalagiri , Sumeet Menon , Phuong Nguyen , David R. Chapman

Lung cancer has a high rate of recurrence in early-stage patients. Predicting the post-surgical recurrence in lung cancer patients has traditionally been approached using single modality information of genomics or radiology images. We…

Image and Video Processing · Electrical Eng. & Systems 2020-02-07 Vaishnavi Subramanian , Minh N. Do , Tanveer Syeda-Mahmood

Image analysis tasks in computational pathology are commonly solved using convolutional neural networks (CNNs). The selection of a suitable CNN architecture and hyperparameters is usually done through exploratory iterative optimization,…

Image and Video Processing · Electrical Eng. & Systems 2022-02-11 Lars Ole Schwen , Daniela Schacherer , Christian Geißler , André Homeyer
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