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Obtaining per-beat information is a key task in the analysis of cardiac electrocardiograms (ECG), as many downstream diagnosis tasks are dependent on ECG-based measurements. Those measurements, however, are costly to produce, especially in…
ECG heartbeat classification plays a vital role in diagnosis of cardiac arrhythmia. The goal of the Physionet/CinC 2021 challenge was to accurately classify clinical diagnosis based on 12, 6, 4, 3 or 2-lead ECG recordings in order to aid…
Electrocardiogram (ECG) datasets tend to be highly imbalanced due to the scarcity of abnormal cases. Additionally, the use of real patients' ECGs is highly regulated due to privacy issues. Therefore, there is always a need for more ECG…
There have been several attempts to quantify the diagnostic distortion caused by algorithms that perform low-dimensional electrocardiogram (ECG) representation. However, there is no universally accepted quantitative measure that allows the…
Electrocardiogram (ECG) data collection during emergency situations is challenging, making ECG data generation an efficient solution for dealing with highly imbalanced ECG training datasets. In this paper, we propose a novel approach for…
Recently, AI-generated content (AIGC) has gained significant traction due to its powerful creation capability. However, the storage and transmission of large amounts of high-quality AIGC images inevitably pose new challenges for recent file…
Genetic Programming (GP) is an evolutionary algorithm commonly used for machine learning tasks. In this paper we present a method that allows GP to transform the representation of a large-scale machine learning dataset into a more compact…
Protein structure prediction has reached revolutionary levels of accuracy on single structures, yet distributional modeling paradigms are needed to capture the conformational ensembles and flexibility that underlie biological function.…
Motivation: The rapid growth in genome-wide association studies (GWAS) in plants and animals has brought about the need for a central resource that facilitates i) performing GWAS, ii) accessing data and results of other GWAS, and iii)…
In this paper, we present a systematic literature review on deep generative models for physiological signals, particularly electrocardiogram (ECG), electroencephalogram (EEG), photoplethysmogram (PPG) and electromyogram (EMG). Compared to…
Motivation: ``Molecular signatures'' or ``gene-expression signatures'' are used to predict patients' characteristics using data from coexpressed genes. Signatures can enhance understanding about biological mechanisms and have diagnostic…
Gene regulatory networks (GRN) are being studied with increasingly precise quantitative tools and can provide a testing ground for ideas regarding the emergence and evolution of complex biological networks. We analyze the global statistical…
Learning ensembles by bagging can substantially improve the generalization performance of low-bias, high-variance estimators, including those evolved by Genetic Programming (GP). To be efficient, modern GP algorithms for evolving (bagging)…
We train a neural network to predict human gene expression levels based on experimental data for rat cells. The network is trained with paired human/rat samples from the Open TG-GATES database, where paired samples were treated with the…
Coexpression of genes or, more generally, similarity in the expression profiles poses an unsurmountable obstacle to inferring the gene regulatory network (GRN) based solely on data from DNA microarray time series. Clustering of genes with…
Each human genome is a 3 billion base pair set of encoding instructions. Decoding the genome using deep learning fundamentally differs from most tasks, as we do not know the full structure of the data and therefore cannot design…
Electrocardiogram~(ECG), a key bioelectrical time-series signal, is crucial for assessing cardiac health and diagnosing various diseases. Given its time-series format, ECG data is often incorporated into pre-training datasets for…
Computational phenotyping has emerged as a practical solution to the incomplete collection of data on gender in electronic health records (EHRs). This approach relies on algorithms to infer a patient's gender using the available data in…
Electronic Health Records (EHR) are data generated during routine clinical care. EHR offer researchers unprecedented phenotypic breadth and depth and have the potential to accelerate the pace of precision medicine at scale. A main EHR…
Plug-and-play language models (PPLMs) enable topic-conditioned natural language generation by pairing large pre-trained generators with attribute models used to steer the predicted token distribution towards the selected topic. Despite…