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Explaining deep learning models in a way that humans can easily understand is essential for responsible artificial intelligence applications. Attribution methods constitute an important area of explainable deep learning. The attribution…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Michal Byra , Henrik Skibbe

Multiple Instance Learning (MIL) is increasingly being used as a support tool within clinical settings for pathological diagnosis decisions, achieving high performance and removing the annotation burden. However, existing approaches for…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Sungrae Hong , Kyungeun Kim , Juhyeon Kim , Sol Lee , Jisu Shin , Chanjae Song , Mun Yong Yi

Multimodal Large Language Models (mLLMs) are often used to answer questions in structured data such as tables in Markdown, JSON, and images. While these models can often give correct answers, users also need to know where those answers come…

Computation and Language · Computer Science 2026-02-18 Yahia Alqurnawi , Preetom Biswas , Anmol Rao , Tejas Anvekar , Chitta Baral , Vivek Gupta

Interpretability of deep learning (DL) systems is gaining attention in medical imaging to increase experts' trust in the obtained predictions and facilitate their integration in clinical settings. We propose a deep visualization method to…

Computer Vision and Pattern Recognition · Computer Science 2022-02-02 Cristina González-Gonzalo , Bart Liefers , Bram van Ginneken , Clara I. Sánchez

The Multiple Instance Learning (MIL) paradigm is attracting plenty of attention in medical imaging classification, where labeled data is scarce. MIL methods cast medical images as bags of instances (e.g. patches in whole slide images, or…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Francisco M. Castro-Macías , Pablo Morales-Álvarez , Yunan Wu , Rafael Molina , Aggelos K. Katsaggelos

We study the attribution problem [28] for deep networks applied to perception tasks. For vision tasks, attribution techniques attribute the prediction of a network to the pixels of the input image. We propose a new technique called…

Computer Vision and Pattern Recognition · Computer Science 2020-04-09 Shawn Xu , Subhashini Venugopalan , Mukund Sundararajan

Lung and colon cancer are serious worldwide health challenges that require early and precise identification to reduce mortality risks. However, diagnosis, which is mostly dependent on histopathologists' competence, presents difficulties and…

Image and Video Processing · Electrical Eng. & Systems 2024-05-15 Mukaffi Bin Moin , Fatema Tuj Johora Faria , Swarnajit Saha , Busra Kamal Rafa , Mohammad Shafiul Alam

Multi-label classification (MLC) of medical images aims to identify multiple diseases and holds significant clinical potential. A critical step is to learn class-specific features for accurate diagnosis and improved interpretability…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Xiaoxiao Cui , Yiran Li , Kai He , Shanzhi Jiang , Mengli Xue , Wentao Li , Junhong Leng , Zhi Liu , Lizhen Cui , Shuo Li

Label-free approaches are attractive in cytological imaging due to their flexibility and cost efficiency. They are supported by machine learning methods, which, despite the lack of labeling and the associated lower contrast, can classify…

Computer Vision and Pattern Recognition · Computer Science 2023-11-27 Stefan Röhrl , Johannes Groll , Manuel Lengl , Simon Schumann , Christian Klenk , Dominik Heim , Martin Knopp , Oliver Hayden , Klaus Diepold

Data attribution methods play a crucial role in understanding machine learning models, providing insight into which training data points are most responsible for model outputs during deployment. However, current state-of-the-art approaches…

Computer Vision and Pattern Recognition · Computer Science 2023-11-08 Vasu Singla , Pedro Sandoval-Segura , Micah Goldblum , Jonas Geiping , Tom Goldstein

Interpretability is crucial to enhance trust in machine learning models for medical diagnostics. However, most state-of-the-art image classifiers based on neural networks are not interpretable. As a result, clinicians often resort to known…

A mutation in the DNA of a single cell that compromises its function initiates leukemia,leading to the overproduction of immature white blood cells that encroach upon the space required for the generation of healthy blood cells.Leukemia is…

Computer Vision and Pattern Recognition · Computer Science 2025-01-27 Md. Abu Ahnaf Mollick , Md. Mahfujur Rahman , D. M. Asadujjaman , Abdullah Tamim , Nosin Anjum Dristi , Md. Takbir Hossen

Interpretability is often an essential requirement in medical imaging. Advanced deep learning methods are required to address this need for explainability and high performance. In this work, we investigate whether additional information…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Luisa Gallee , Meinrad Beer , Michael Goetz

eXplanation Based Learning (XBL) is a form of Interactive Machine Learning (IML) that provides a model refining approach via user feedback collected on model explanations. Although the interactivity of XBL promotes model transparency, XBL…

Machine Learning · Computer Science 2023-07-13 Misgina Tsighe Hagos , Kathleen M. Curran , Brian Mac Namee

Deep learning models show promise in digital pathology, but their opaque decision-making processes limit trust and clinical adoption. To address this challenge, we present HIPPO, an explainable AI method for analyzing weakly-supervised…

Tissues and Organs · Quantitative Biology 2025-12-10 Jakub R. Kaczmarzyk , Chanwoo Kim , Soham Gadgil , Deepika Savant , Zhen Zhao , Joel H. Saltz , Su-In Lee , Peter K. Koo

Multiple instance learning (MIL) has emerged as the dominant paradigm for whole slide image (WSI) analysis in computational pathology, achieving strong diagnostic performance through patch-level feature aggregation. However, existing MIL…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Yiran Song , Yikai Zhang , Shuang Zhou , Guojun Xiong , Xiaofeng Yang , Nian Wang , Fenglong Ma , Rui Zhang , Mingquan Lin

Attribution methods shed light on the explainability of data-driven approaches such as deep learning models by uncovering the most influential features in a to-be-explained decision. While determining feature attributions via gradients…

Machine Learning · Computer Science 2024-05-15 Yi Cai , Gerhard Wunder

Earlier diagnosis of Leukemia can save thousands of lives annually. The prognosis of leukemia is challenging without the morphological information of White Blood Cells (WBC) and relies on the accessibility of expensive microscopes and the…

Image and Video Processing · Electrical Eng. & Systems 2024-05-20 Abdul Rehman , Talha Meraj , Aiman Mahmood Minhas , Ayisha Imran , Mohsen Ali , Waqas Sultani

With the development of computational pathology, deep learning methods for Gleason grading through whole slide images (WSIs) have excellent prospects. Since the size of WSIs is extremely large, the image label usually contains only…

Computer Vision and Pattern Recognition · Computer Science 2022-06-28 Hao Bian , Zhuchen Shao , Yang Chen , Yifeng Wang , Haoqian Wang , Jian Zhang , Yongbing Zhang