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Detection of various lesions in brain MRI is clinically critical, but challenging due to the diversity of lesions and variability in imaging conditions. Current unsupervised learning methods detect anomalies mainly through reconstructing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Tao Yang , Xiuying Wang , Hao Liu , Guanzhong Gong , Lian-Ming Wu , Yu-Ping Wang , Lisheng Wang

The identification of lesion within medical image data is necessary for diagnosis, treatment and prognosis. Segmentation and classification approaches are mainly based on supervised learning with well-paired image-level or voxel-level…

Computer Vision and Pattern Recognition · Computer Science 2019-04-09 Liyan Sun , Jiexiang Wang , Yue Huang , Xinghao Ding , Hayit Greenspan , John Paisley

Today's Cyber-Physical Systems (CPSs) are large, complex, and affixed with networked sensors and actuators that are targets for cyber-attacks. Conventional detection techniques are unable to deal with the increasingly dynamic and complex…

Machine Learning · Computer Science 2019-01-16 Dan Li , Dacheng Chen , Jonathan Goh , See-kiong Ng

Semi-supervised and unsupervised Generative Adversarial Networks (GAN)-based methods have been gaining popularity in anomaly detection task recently. However, GAN training is somewhat challenging and unstable. Inspired from previous work in…

Computer Vision and Pattern Recognition · Computer Science 2019-02-20 Ha Son Vu , Daisuke Ueta , Kiyoshi Hashimoto , Kazuki Maeno , Sugiri Pranata , Sheng Mei Shen

Generative adversarial networks (GANs) are a class of unsupervised machine learning algorithms that can produce realistic images from randomly-sampled vectors in a multi-dimensional space. Until recently, it was not possible to generate…

Computer Vision and Pattern Recognition · Computer Science 2018-05-10 Andrew Beers , James Brown , Ken Chang , J. Peter Campbell , Susan Ostmo , Michael F. Chiang , Jayashree Kalpathy-Cramer

Data diversity is critical to success when training deep learning models. Medical imaging data sets are often imbalanced as pathologic findings are generally rare, which introduces significant challenges when training deep learning models.…

Computer Vision and Pattern Recognition · Computer Science 2018-09-17 Hoo-Chang Shin , Neil A Tenenholtz , Jameson K Rogers , Christopher G Schwarz , Matthew L Senjem , Jeffrey L Gunter , Katherine Andriole , Mark Michalski

Medical imaging data suffers from the limited availability of annotation because annotating 3D medical data is a time-consuming and expensive task. Moreover, even if the annotation is available, supervised learning-based approaches suffer…

Image and Video Processing · Electrical Eng. & Systems 2020-11-12 Abinav Ravi Venkatakrishnan , Seong Tae Kim , Rami Eisawy , Franz Pfister , Nassir Navab

Anomalies can be defined as any non-random structure which deviates from normality. Anomaly detection methods reported in the literature are numerous and diverse, as what is considered anomalous usually varies depending on particular…

Computer Vision and Pattern Recognition · Computer Science 2021-10-07 Matias Tailanian , Pablo Musé , Álvaro Pardo

Generative Adversarial Networks (GANs) advance face synthesis through learning the underlying distribution of observed data. Despite the high-quality generated faces, some minority groups can be rarely generated from the trained models due…

Computer Vision and Pattern Recognition · Computer Science 2021-03-30 Shuhan Tan , Yujun Shen , Bolei Zhou

In this paper, we study unsupervised anomaly detection algorithms that learn a neural network representation, i.e. regular patterns of normal data, which anomalies are deviating from. Inspired by a similar concept in engineering, we refer…

Machine Learning · Computer Science 2025-11-12 Simon Klüttermann , Tim Katzke , Emmanuel Müller

Network anomaly detection aims to find network elements (e.g., nodes, edges, subgraphs) with significantly different behaviors from the vast majority. It has a profound impact in a variety of applications ranging from finance, healthcare to…

Machine Learning · Computer Science 2021-02-23 Kaize Ding , Qinghai Zhou , Hanghang Tong , Huan Liu

Unsupervised anomaly detection is a challenging task. Autoencoders (AEs) or generative models are often employed to model the data distribution of normal inputs and subsequently identify anomalous, out-of-distribution inputs by high…

Machine Learning · Computer Science 2025-06-12 Yalin Liao , Austin J. Brockmeier

Pseudo-normality synthesis, which computationally generates a pseudo-normal image from an abnormal one (e.g., with lesions), is critical in many perspectives, from lesion detection, data augmentation to clinical surgery suggestion. However,…

Computer Vision and Pattern Recognition · Computer Science 2021-06-30 Yuanqi Du , Quan Quan , Hu Han , S. Kevin Zhou

Generative Adversarial Networks (GANs) have recently achieved unprecedented success in photo-realistic image synthesis from low-dimensional random noise. The ability to synthesize high-quality content at a large scale brings potential risks…

Computer Vision and Pattern Recognition · Computer Science 2021-05-28 Celia Cintas , Skyler Speakman , Girmaw Abebe Tadesse , Victor Akinwande , Edward McFowland , Komminist Weldemariam

In standard generative deep learning models, such as autoencoders or GANs, the size of the parameter set is proportional to the complexity of the generated data distribution. A significant challenge is to deploy resource-hungry deep…

Machine Learning · Computer Science 2021-10-29 Shreshth Tuli , Shikhar Tuli , Giuliano Casale , Nicholas R. Jennings

In this research, we introduce an innovative method for synthesizing medical images using generative adversarial networks (GANs). Our proposed GANs method demonstrates the capability to produce realistic synthetic images even when trained…

Image and Video Processing · Electrical Eng. & Systems 2024-06-28 Yinqiu Feng , Bo Zhang , Lingxi Xiao , Yutian Yang , Tana Gegen , Zexi Chen

Anomaly detection in dynamic graphs is a critical task with broad real-world applications, including social networks, e-commerce, and cybersecurity. Most existing methods assume that normal patterns remain stable over time; however, this…

Machine Learning · Computer Science 2025-09-23 Xiaoyang Xu , Xiaofeng Lin , Koh Takeuchi , Kyohei Atarashi , Hisashi Kashima

Harnessing the power of deep neural networks in the medical imaging domain is challenging due to the difficulties in acquiring large annotated datasets, especially for rare diseases, which involve high costs, time, and effort for…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Md Mahfuzur Rahman Siddiquee , Jay Shah , Teresa Wu , Catherine Chong , Todd J. Schwedt , Gina Dumkrieger , Simona Nikolova , Baoxin Li

Anomaly detection is nowadays increasingly used in industrial applications and processes. One of the main fields of the appliance is the visual inspection for surface anomaly detection, which aims to spot regions that deviate from…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Niccolò Ferrari , Michele Fraccaroli , Evelina Lamma

Anomaly localization in images -- identifying regions that deviate from normal patterns -- is vital in applications such as medical diagnosis and industrial inspection. A recent trend is the use of image generation models in anomaly…

Machine Learning · Statistics 2026-04-28 Teruyuki Katsuoka , Tomohiro Shiraishi , Daiki Miwa , Vo Nguyen Le Duy , Ichiro Takeuchi
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