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Early and accurate diagnosis of Alzheimer's disease (AD) and its prodromal period mild cognitive impairment (MCI) is essential for the delayed disease progression and the improved quality of patients'life. The emerging computer-aided…

Image and Video Processing · Electrical Eng. & Systems 2021-07-29 Fan Zhang , Bo Pan , Pengfei Shao , Peng Liu , Shuwei Shen , Peng Yao , Ronald X. Xu

Automated detection of sclerotic metastases (bone lesions) in Computed Tomography (CT) images has potential to be an important tool in clinical practice and research. State-of-the-art methods show performance of 79% sensitivity or…

Computer Vision and Pattern Recognition · Computer Science 2014-07-23 Holger R. Roth , Jianhua Yao , Le Lu , James Stieger , Joseph E. Burns , Ronald M. Summers

The work presented explores the use of denoising autoencoders (DAE) for brain lesion detection, segmentation and false positive reduction. Stacked denoising autoencoders (SDAE) were pre-trained using a large number of unlabeled patient…

Computer Vision and Pattern Recognition · Computer Science 2017-01-11 Varghese Alex , Kiran Vaidhya , Subramaniam Thirunavukkarasu , Chandrasekharan Kesavdas , Ganapathy Krishnamurthi

Currently, a significant amount of research has been done in field of Remote Sensing with the use of deep learning techniques. The introduction of Marine Debris Archive (MARIDA), an open-source dataset with benchmark results, for marine…

Computer Vision and Pattern Recognition · Computer Science 2022-10-18 Azhan Mohammed

The detection of new multiple sclerosis (MS) lesions is an important marker of the evolution of the disease. The applicability of learning-based methods could automate this task efficiently. However, the lack of annotated longitudinal data…

Image and Video Processing · Electrical Eng. & Systems 2022-06-17 Reda Abdellah Kamraoui , Boris Mansencal , José V Manjon , Pierrick Coupé

This paper presents a multimodal deep learning framework that utilizes advanced image techniques to improve the performance of clinical analysis heavily dependent on routinely acquired standard images. More specifically, we develop a joint…

Computer Vision and Pattern Recognition · Computer Science 2024-02-29 Jiarui Xing , Nian Wu , Kenneth Bilchick , Frederick Epstein , Miaomiao Zhang

Brain atlases are essential for reducing the dimensionality of neuroimaging data and enabling interpretable analysis. However, most existing atlases are predefined, group-level templates with limited flexibility and resolution. We present…

Neurons and Cognition · Quantitative Biology 2025-09-23 Mo Wang , Kaining Peng , Jingsheng Tang , Hongkai Wen , Quanying Liu

Supervised deep learning techniques show promise in medical image analysis. However, they require comprehensive annotated data sets, which poses challenges, particularly for rare diseases. Consequently, unsupervised anomaly detection (UAD)…

Image and Video Processing · Electrical Eng. & Systems 2024-03-22 Finn Behrendt , Debayan Bhattacharya , Lennart Maack , Julia Krüger , Roland Opfer , Robin Mieling , Alexander Schlaefer

Synthesizing longitudinal medical images at controllable disease stages while preserving patient-specific anatomy is hindered by the entanglement of pathological textures and structural features. We address this challenge for ulcerative…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Umut Dundar , Alptekin Temizel

Residual network (ResNet) and densely connected network (DenseNet) have significantly improved the training efficiency and performance of deep convolutional neural networks (DCNNs) mainly for object classification tasks. In this paper, we…

Image and Video Processing · Electrical Eng. & Systems 2020-04-29 Mina Jafari , Dorothee Auer , Susan Francis , Jonathan Garibaldi , Xin Chen

High resolution is crucial for precise segmentation in fundus images, yet handling high-resolution inputs incurs considerable GPU memory costs, with diminishing performance gains as overhead increases. To address this issue while tackling…

Computer Vision and Pattern Recognition · Computer Science 2025-04-14 Ziyuan Ding , Yixiong Liang , Shichao Kan , Qing Liu

This paper introduces a concept of layer aggregation to describe how information from previous layers can be reused to better extract features at the current layer. While DenseNet is a typical example of the layer aggregation mechanism, its…

Computer Vision and Pattern Recognition · Computer Science 2021-10-25 Jingyu Zhao , Yanwen Fang , Guodong Li

Diabetic retinopathy is one of the leading causes of preventable blindness in the world. Its earliest sign are red lesions, a general term that groups both microaneurysms and hemorrhages. In daily clinical practice, these lesions are…

Computer Vision and Pattern Recognition · Computer Science 2017-10-16 José Ignacio Orlando , Elena Prokofyeva , Mariana del Fresno , Matthew B. Blaschko

The reliable segmentation of retinal vasculature can provide the means to diagnose and monitor the progression of a variety of diseases affecting the blood vessel network, including diabetes and hypertension. We leverage the power of…

Image and Video Processing · Electrical Eng. & Systems 2019-07-23 Ali Hatamizadeh , Hamid Hosseini , Zhengyuan Liu , Steven D. Schwartz , Demetri Terzopoulos

Unsupervised domain adaptation (UDA) aims to adapt a model trained on the source domain (e.g. synthetic data) to the target domain (e.g. real-world data) without requiring further annotations on the target domain. This work focuses on UDA…

Computer Vision and Pattern Recognition · Computer Science 2022-07-27 Lukas Hoyer , Dengxin Dai , Luc Van Gool

Frozen pretrained image representations are widely used for transfer learning: a backbone is kept fixed, feature vectors are extracted, and a lightweight classifier is trained on top. This pipeline usually feeds the full feature vector to…

Machine Learning · Computer Science 2026-05-12 Indar Kumar , Girish Karhana , Sai Krishna Jasti , Ankit Hemant Lade

Medical image segmentation based on deep learning often fails when deployed on images from a different domain. The domain adaptation methods aim to solve domain-shift challenges, but still face some problems. The transfer learning methods…

Computer Vision and Pattern Recognition · Computer Science 2023-06-16 Zhusi Zhong , Jie Li , Lulu Bi , Li Yang , Ihab Kamel , Rama Chellappa , Xinbo Gao , Harrison Bai , Zhicheng Jiao

We introduce Deep Linear Discriminant Analysis (DeepLDA) which learns linearly separable latent representations in an end-to-end fashion. Classic LDA extracts features which preserve class separability and is used for dimensionality…

Machine Learning · Computer Science 2016-02-18 Matthias Dorfer , Rainer Kelz , Gerhard Widmer

Methods for unsupervised domain adaptation (UDA) help to improve the performance of deep neural networks on unseen domains without any labeled data. Especially in medical disciplines such as histopathology, this is crucial since large…

Computer Vision and Pattern Recognition · Computer Science 2023-02-03 Kevin Thandiackal , Luigi Piccinelli , Pushpak Pati , Orcun Goksel

Deformable medical image registration is a fundamental task in medical image analysis with applications in disease diagnosis, treatment planning, and image-guided interventions. Despite significant advances in deep learning based…

Machine Learning · Computer Science 2026-02-10 Muhammad Zafar Iqbal , Ghazanfar Farooq Siddiqui , Anwar Ul Haq , Imran Razzak
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