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Benchmark datasets for digital dermatology unwittingly contain inaccuracies that reduce trust in model performance estimates. We propose a resource-efficient data-cleaning protocol to identify issues that escaped previous curation. The…

Optical imaging below the limit of light diffraction offers an unprecedented opportunity to study outlook, organization, interactions or in-situ functioning of sub-micrometer, highly transparent objects such as subcellular structures in…

Melanoma is a type of skin cancer with the most rapidly increasing incidence. Early detection of melanoma using dermoscopy images significantly increases patients' survival rate. However, accurately classifying skin lesions by eye,…

Computer Vision and Pattern Recognition · Computer Science 2019-02-14 Xiaoxiao Li , Junyan Wu , Eric Z. Chen , Hongda Jiang

One important characteristic of modern fault classification systems is the ability to flag the system when faced with previously unseen fault types. This work considers the unknown fault detection capabilities of deep neural network-based…

Machine Learning · Computer Science 2024-03-27 Nurettin Sergin , Jiayu Huang , Tzyy-Shuh Chang , Hao Yan

The field of histology relies heavily on antiquated tissue processing and staining techniques that limit the efficiency of pathologic diagnoses of cancer and other diseases. Current staining and advanced labeling methods are often…

Optimizing neural networks with noisy labels is a challenging task, especially if the label set contains real-world noise. Networks tend to generalize to reasonable patterns in the early training stages and overfit to specific details of…

Computer Vision and Pattern Recognition · Computer Science 2023-04-27 Timo Kaiser , Lukas Ehmann , Christoph Reinders , Bodo Rosenhahn

Microscopy image enhancement plays a pivotal role in understanding the details of biological cells and materials at microscopic scales. In recent years, there has been a significant rise in the advancement of microscopy image enhancement,…

Image and Video Processing · Electrical Eng. & Systems 2025-09-29 Debasish Dutta , Neeharika Sonowal , Risheraj Barauh , Deepjyoti Chetia , Sanjib Kr Kalita

Cytology is a low-cost and non-invasive diagnostic procedure employed to support the diagnosis of a broad range of pathologies. Computer Vision technologies, by automatically generating quantitative and objective descriptions of…

Recent technological advances have expanded the availability of high-throughput biological datasets, enabling the reliable design of digital twins of biomedical systems or patients. Such computational tools represent key reaction networks…

Quantitative Methods · Quantitative Biology 2025-09-03 Clémence Métayer , Annabelle Ballesta , Julien Martinelli

Clinical images are vital for diagnosing and monitoring skin diseases, and their importance has increased with the growing popularity of machine learning. Lack of standards has stifled innovation in dermatological imaging, unlike other…

Information Retrieval · Computer Science 2025-10-29 Bell Raj Eapen , Feroze Kaliyadan , Ashique Karalikkattil T

Data cleaning consumes about 80% of the time spent on data analysis for clinical research projects. This is a much bigger problem in the era of big data and machine learning in the field of medicine where large volumes of data are being…

Medical Physics · Physics 2018-01-03 Timothy Rozario , Troy Long , Mingli Chen , Weiguo Lu , Steve Jiang

Diagnostic imaging plays a critical role in healthcare, serving as a fundamental asset for timely diagnosis, disease staging and management as well as for treatment choice, planning, guidance, and follow-up. Among the diagnostic imaging…

Signal Processing · Electrical Eng. & Systems 2021-09-24 Ruud JG van Sloun , Jong Chul Ye , Yonina C Eldar

Multi-label classification, which involves assigning multiple labels to a single input, has emerged as a key area in both research and industry due to its wide-ranging applications. Designing effective loss functions is crucial for…

Machine Learning · Computer Science 2025-01-06 Alexandre Audibert , Aurélien Gauffre , Massih-Reza Amini

Deep learning-based recommender systems have achieved remarkable success in recent years. However, these methods usually heavily rely on labeled data (i.e., user-item interactions), suffering from problems such as data sparsity and…

Information Retrieval · Computer Science 2023-10-12 Mengyuan Jing , Yanmin Zhu , Tianzi Zang , Ke Wang

Machine learning-based medical anomaly detection is an important problem that has been extensively studied. Numerous approaches have been proposed across various medical application domains and we observe several similarities across these…

Machine Learning · Computer Science 2021-04-14 Tharindu Fernando , Harshala Gammulle , Simon Denman , Sridha Sridharan , Clinton Fookes

Digital scans of analogue photographic film typically contain artefacts such as dust and scratches. Automated removal of these is an important part of preservation and dissemination of photographs of historical and cultural importance.…

Computer Vision and Pattern Recognition · Computer Science 2023-02-21 Daniela Ivanova , John Williamson , Paul Henderson

Serial femtosecond crystallography at X-ray free electron laser facilities opens a new era for the determination of crystal structure. However, the data processing of those experiments is facing unprecedented challenge, because the total…

Materials Science · Physics 2023-09-22 Jianan Xie , Ji Liu , Chi Zhang , Xihui Chen , Ping Huai , Jie Zheng , Xiaofeng Zhang

Recently, deep learning approaches have become the main research frontier for biological image reconstruction and enhancement problems thanks to their high performance, along with their ultra-fast inference times. However, due to the…

Image and Video Processing · Electrical Eng. & Systems 2022-03-18 Mehmet Akçakaya , Burhaneddin Yaman , Hyungjin Chung , Jong Chul Ye

Hematoxylin and Eosin (H&E) staining is widely regarded as the standard in pathology for diagnosing diseases and tracking tumor recurrence. While H&E staining shows tissue structures, it lacks the ability to reveal specific proteins that…

Image and Video Processing · Electrical Eng. & Systems 2025-05-21 Tushar Kataria , Beatrice Knudsen , Shireen Y. Elhabian

Label-free approaches are attractive in cytological imaging due to their flexibility and cost efficiency. They are supported by machine learning methods, which, despite the lack of labeling and the associated lower contrast, can classify…

Computer Vision and Pattern Recognition · Computer Science 2023-11-27 Stefan Röhrl , Johannes Groll , Manuel Lengl , Simon Schumann , Christian Klenk , Dominik Heim , Martin Knopp , Oliver Hayden , Klaus Diepold